Effect of aerobic interval training and caffeine on blood platelet function

Medicine and Science in Sports and Exercise

Volumn 45, Issue 2, 2013, Pages 342-350

  Whittaker, Joshua P ^a   Linden, Matthew D ^a   Coffey, Vernon G ^a  

^a RMIT UNIVERSITY   (Australia)

Author keywords

aggregation; Exercise; platelet activation; thrombosis

Indexed keywords

CAFFEINE;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; BLOOD CLOTTING PARAMETERS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; EXERCISE; HUMAN; MALE; OXYGEN CONSUMPTION; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE;

ANALYSIS OF VARIANCE; BLOOD PLATELETS; CAFFEINE; EXERCISE; HUMANS; MALE; OXYGEN CONSUMPTION; PLATELET FUNCTION TESTS; YOUNG ADULT;

EID: 84872860622     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0b013e31827039db     Document Type: Article

References (41)

1. Aldemir H, Kilic N. The effect of time of day and exercise on platelet functions and platelet-nuetrophil aggregates in healthy male subjects. Mol Cell Biochem. 2005;280(2):119-24.
2. Bath PM, Butterworth RJ. Platelet size: measurement, physiology and vascular disease. Blood Coagul Fibrinolysis. 1996;7(2):157-61.
3. Berger AJ, Alford K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med J Aust. 2009;190(1):41-3.
4. Braekkan SK, Mathiesen EB, Njolstad I, Wilsgaard T, Stormer J, Hansen JB. Mean platelet volume is a risk factor for venous thromboembolism: the TromsL Study, TromsL, Norway. J Thromb Haemost. 2010;8(1):157-62.
5. Burke LM. Caffeine and sports performance. Appl Physiol Nutr Metab. 2008;33(6):1319-34.
6. Cadroy Y, Pillard F, Sakariassen KS, Boneu B, Riviere D. Strenuous but not moderate exercise increases the thrombotic tendency in healthy sedentary male volunteers. J Appl Physiol. 2002;93(3):829-33.
7. Chamberlain K, Tong M, Penington D. Properties of the exchangeable splenic platelets released into the circulation during exercise-induced thrombocytosis. Am J Hematol. 1990;34(3):161-8.
8. Chicharro JL, Sanchez O, Bandres F, et al. Blood coagulability changes during exercise and its relationship with the anaerobic threshold. Thromb Res. 1995;79(5):515-22.
9. Chu SG, Becker RC, Berger PB, et al. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and metaanalysis. J Thromb Haemost. 2010;8(1):148-56.
10. Dill DB, Costill DL. Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J Appl Physiol. 1974;37(2):247-8.
11. Endler G, Klimesch A, Sunder-Plassmann H, et al. Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease. Br J Haematol. 2002;117(2): 399-404.
12. Ersoz G, Zergeroglu AM, Ficicilar H, et al. Effect of submaximal and incremental upper extremity exercise on platelet function and the role of blood shear stress. Thromb Res. 2003;108(5-6): 297-301.
13. Fredholm BB. Adenosine, adenosine receptors and the actions of caffeine. Pharmacol Toxicol. 1995;76(2):93-101.
14. Graham TE, Spriet LL. Metabolic, catecholamine, and exercise performance responses to various doses of caffeine. J Appl Physiol. 1995;78(3):867-74.
15. Hilberg T, Menzel K, Glaser D, Zimmermann S, Gabriel HHW. Exercise intensity: platelet function and platelet-leukocyte conjugate formation in untrained subjects. Thromb Res. 2008;122(1): 77-84.
16. Hilberg T, Prasa D, Sturzebecher J, Glaser D, Shneider K, Gabriel H. Blood coagulation and fibrinolysis after extreme short-term exercise. Thromb Res. 2003;109(5-6):271-7.
17. Ikarugi H, Taka T, Nakajima S, et al. Norepinephrine, but not epinephrine, enhances platelet reactivity and coagulation after exercise in humans. J Appl Physiol. 1999;86(1):133-8.
18. Jenkins NT, Trilk JL, Singhal A, O'Connor PJ, Cureton KJ. Ergogenic effects of low doses of caffeine on cycling performance. Int J Sport Nutr Exerc Metab. 2008;18(3):328-42.
19. Jenkins RR. Free radical chemistry. Relationship to exercise. Sports Med. 1998;5(3):156-70.
20. Kestin AS, Ellis PA, Barnard MR, Errichetti A, Rosner BA, Michelson AD. Effect of strenuous exercise on platelet activation state and reactivity. Circulation. 1993;88(4):1502-11.
21. Klysner R, Andersen PH, Geisler A, Winther K. Characterization of the beta-adrenergic receptor on the human platelet: a beta 2-subtype. Acta Pharmacol Toxicol. 1984;54(4):265-9.
22. Knudsen J, Brodthagen U, Gormsen J, Jordal R, NLrregaard-Hansen K, Paulev P. Platelet function and fibrinolytic activity following distance running. Scand J Haematol. 1982;29(5):425-30.
23. Kratz A, Wood MJ, Siegel AJ, Hiers JR, Van Cott EM. Effects of marathon running on platelet activation markers. Am J Clin Pathol. 2006;125(2):296-300.
24. Kumar A, Kar S, Fay WP. Thrombosis, physical activity, and acute coronary syndromes. J Appl Physiol. 2011;111(2):599-605.
25. Li N, Wallen H, Hjemdahl P. Evidence for prothrombotic effects of exercises and limited protection by aspirin. Circulation. 1999; 100(13):1374-9.
26. Linden MD, Barnard MR, Frelinger AL, Michelson AD, Przyklenk K. Effect of adenosine A2 receptor stimulation on platelet activation-aggregation: differences between canine and human models. Thromb Res. 2008;121(5):689-98.
27. Linden MD, Frelinger AL, Barnard MR, Przyklenk K, Furman MI, Michelson AD. Application of flow cytometry to platelet disorders. Semin Thromb Hemost. 2004;30(5):501-11.
28. Linden MD, Furman MI, Frelinger AL, et al. Indices of platelet activation and the stability of coronary artery disease. J Thromb Haemost. 2007;5(4):761-5.
29. Michelson AD, Barnard MR, Hechtman HB, et al. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci USA. 1996;93(21):11877-82.
30. Mittleman MA, Maclure M, Tofler GH, Sherwood JB, Goldberg RJ, Muller JE. Triggering of acute myocardial infarction by heavy physical exertion. New Engl J Med. 1993;329(23):1677-83.
31. Naesh OI, Trap-Jensen J, Lund JO. Post-exercise platelet activation-aggregation and release in relation to dynamic exercise. Clin Physiol. 1990;10(3):221-30.
32. Peters MJ, Heyderman RS, Hatch DJ, Klein NJ. Investigation of platelet-neutrophil interactions in whole blood flow cytometry. J Immunol Methods. 1997;209(2):125-35.
33. Rock G, Tittley P, Pipe A. Coagulation factor changes following endurance exercise. Clin J Sports Med. 1997;7(2):94-9.
34. Sakita S, Kishi Y, Numano F. Acute vigorous exercise attenuates sensitivity of platelets to nitric oxide. Thromb Res. 1997;87(5): 461-71.
35. Singh I, Quinn H, Mok M, et al. The effect of exercise and training status on platelet activation: do cocoa polyphenols play a role? Platelets. 2006;17(6):361-7.
36. Tofler GH, Stone PH, Maclure M, et al. Analysis of possible triggers of acute myocardial infarction (the MILIS study). Am J Cardiol. 1990;66(1):22-7.
37. Varani K, Portaluppi F, Gessi S, et al. Dose and time effects of caffeine intake on human platelet adenosine A2A receptor: functional and biochemical aspects. Circulation. 2000; 102(3):285-9.
38. Varani K, Portaluppi F, Merighi S, Ongini E, Belardinelli L, Borea AP. Caffeine alters A2A adenosine receptors and their function in human platelets. Circulation. 1999;99(19):2499-502.
39. Wang JS, Jen CJ, Kung HC, Lin LJ, Hsiue TR, Chen HI. Different effects of strenuous exercise and moderate exercise on platelet function in men. Circulation. 1994;90(6):2877-85.
40. Willich SN, Lewis M, Lowel H, Arntz H, Schubert F, Schroder R. Physical exertion as a trigger of acute myocardial infarction. Triggers and mechanisms of myocardial infarction study group. New Engl J Med. 1993;329(23):1684-90.
41. Worthley MI, Prabhu A, De Sciscio P, Schultz C, Sanders P, Willoughby SR. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med. 2010;123(2):184-7.