Caffeine alters A(2A) adenosine receptors and their function in human platelets

Circulation

Volumn 99, Issue 19, 1999, Pages 2499-2502

  Varani, Katia ^a   Portaluppi, Francesco ^a   Merighi, Stefania ^a   Ongini, Ennio ^b   Belardinelli, Luiz ^c   Borea, Pier Andrea ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b San Raffaele Science Park   (Italy)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Adenosine; Caffeine; Platelet aggregation inhibitors; Platelets; Receptors

Indexed keywords

2 HEXYNYL 5' N ETHYLCARBOXAMIDOADENOSINE; 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; CAFFEINE; CYCLIC AMP; TRITIUM; UNCLASSIFIED DRUG; 2 HEXYNYLADENOSINE 5' N ETHYLCARBOXAMIDE; 2-HEXYNYLADENOSINE-5'-N-ETHYLCARBOXAMIDE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE RECEPTOR; ANTITHROMBOCYTIC AGENT; DRUG DERIVATIVE; PHOSPHODIESTERASE INHIBITOR;

ADULT; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RECEPTOR BINDING; THROMBOCYTE AGGREGATION; DRUG EFFECT; METABOLISM; MIDDLE AGED; PATHOLOGY; SIGNAL TRANSDUCTION; THROMBOCYTE;

ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); ADULT; BLOOD PLATELETS; CAFFEINE; CYCLIC AMP; FEMALE; HUMANS; MALE; MIDDLE AGED; PHOSPHODIESTERASE INHIBITORS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; RECEPTORS, PURINERGIC P1; SIGNAL TRANSDUCTION;

EID: 0033580489     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.99.19.2499     Document Type: Article

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