Induction of apoptosis by a potent caffeic acid derivative, caffeic acid undecyl ester, is mediated by mitochondrial damage in NALM-6 human B cell leukemia cells

Oncology Reports

Volumn 29, Issue 2, 2013, Pages 425-429

  Tomizawa, Ayako ^a   Kanno, Syu Ichi ^a   Osanai, Yuu ^a   Goto, Akane ^a   Sato, Chizuru ^a   Yomogida, Shin ^a   Ishikawa, Masaaki ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Bcl 2; Caffeic acid; Mitochondria; NALM 6

Indexed keywords

ANTILEUKEMIC AGENT; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CAFFEIC ACID DERIVATIVE; CAFFEIC ACID PHENETHYL ESTER; CAFFEIC ACID UNDECYL ESTER; CASPASE 3; CASPASE INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; B CELL LEUKEMIA; CELL STRAIN NALM; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME MODIFICATION; GENE SILENCING; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANALYSIS OF VARIANCE; APOPTOSIS; CAFFEIC ACIDS; CASPASE 3; CELL SURVIVAL; DOWN-REGULATION; GENES, BCL-2; HUMANS; INHIBITORY CONCENTRATION 50; LEUKEMIA, B-CELL; LYMPHOCYTES; MEMBRANE POTENTIAL, MITOCHONDRIAL; PHENYLETHYL ALCOHOL; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 84872819310     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.2163     Document Type: Article

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