Nanocarrier-cell surface adhesive and hydrodynamic interactions: Ligand-receptor bond sensitivity study

Journal of Nanotechnology in Engineering and Medicine

Volumn 3, Issue 3, 2012, Pages

  Uma, B ^a   Radhakrishnan, R ^b   Eckmann, D M ^a   Ayyaswamy, P S ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

fluctuating hydrodynamics; generalized Langevin dynamics; hybrid numerical simulation; ligand receptor interaction; nanocarrier motion; targeted drug delivery

Indexed keywords

ADHESIVE INTERACTION; ANALYTICAL RESULTS; ARBITRARY LAGRANGIAN EULERIAN; EQUIPARTITION; FREE ENERGY DENSITY; HYBRID APPROACH; HYDRODYNAMIC INTERACTION; LANGEVIN DYNAMICS; LIGAND-RECEPTOR; LIGAND-RECEPTOR INTERACTIONS; MICROSCOPIC INTERACTION; MULTI-SCALE MODELING; NANOCARRIERS; NEWTONIANS; NUMERICAL EVALUATIONS; POTENTIAL OF MEAN FORCE; REACTION COORDINATES; RECEPTOR-LIGAND BONDS; SENSITIVITY STUDIES; STATIONARY FLUIDS; TARGETED DRUG DELIVERY;

CELL MEMBRANES; COMPUTER SIMULATION; DRUG DELIVERY; DYNAMICS; FINITE ELEMENT METHOD; LIGANDS; MEDICAL APPLICATIONS;

HYDRODYNAMICS;

NANOCARRIER;

ANALYTIC METHOD; ANALYTICAL PARAMETERS; ARTICLE; CELL ADHESION; CELL SURFACE; CHEMICAL BOND; FINITE ELEMENT ANALYSIS; HYDRODYNAMICS; LAGRANGIAN EULERIAN METHOD; LANGEVIN DYNAMICS METHOD; MICROSCOPY; MOLECULAR DYNAMICS; STATISTICAL ANALYSIS; TEMPERATURE;

EID: 84872802192     PISSN: 19492944     EISSN: 19492952     Source Type: Journal    
DOI: 10.1115/1.4007522     Document Type: Article

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