메뉴 건너뛰기




Volumn 8, Issue 1, 2013, Pages

IKKi Deficiency Promotes Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE B;

EID: 84872792376     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053412     Document Type: Article
Times cited : (23)

References (38)
  • 1
    • 79959950762 scopus 로고    scopus 로고
    • Novel therapeutic targets for the treatment of heart failure
    • Tamargo J, Lopez-Sendon J, (2011) Novel therapeutic targets for the treatment of heart failure. Nat Rev Drug Discov 10: 536-555.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 536-555
    • Tamargo, J.1    Lopez-Sendon, J.2
  • 2
    • 53549085406 scopus 로고    scopus 로고
    • ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the diagnosis and treatment of acute and chronic heart failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM)
    • Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, et al. (2008) ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the diagnosis and treatment of acute and chronic heart failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM). Eur J Heart Fail 10: 933-989.
    • (2008) Eur J Heart Fail , vol.10 , pp. 933-989
    • Dickstein, K.1    Cohen-Solal, A.2    Filippatos, G.3    McMurray, J.J.4    Ponikowski, P.5
  • 3
    • 63849177462 scopus 로고    scopus 로고
    • 2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation
    • Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, et al. (2009) 2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation. J Am Coll Cardiol 53: e1-e90.
    • (2009) J Am Coll Cardiol , vol.53
    • Hunt, S.A.1    Abraham, W.T.2    Chin, M.H.3    Feldman, A.M.4    Francis, G.S.5
  • 4
    • 77649091020 scopus 로고    scopus 로고
    • Executive summary: heart disease and stroke statistics-2010 update: a report from the American Heart Association
    • Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, et al. (2010) Executive summary: heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation 121: 948-954.
    • (2010) Circulation , vol.121 , pp. 948-954
    • Lloyd-Jones, D.1    Adams, R.J.2    Brown, T.M.3    Carnethon, M.4    Dai, S.5
  • 7
    • 1042286928 scopus 로고    scopus 로고
    • The imbalance between oxygen demand and supply as a potential mechanism in the pathophysiology of heart failure: the role of microvascular growth and abnormalities
    • De Boer RA, Pinto YM, Van Veldhuisen DJ, (2003) The imbalance between oxygen demand and supply as a potential mechanism in the pathophysiology of heart failure: the role of microvascular growth and abnormalities. Microcirculation 10: 113-126.
    • (2003) Microcirculation , vol.10 , pp. 113-126
    • De Boer, R.A.1    Pinto, Y.M.2    Van Veldhuisen, D.J.3
  • 8
    • 2442651359 scopus 로고    scopus 로고
    • A decade of discoveries in cardiac biology
    • Olson EN, (2004) A decade of discoveries in cardiac biology. Nat Med 10: 467-474.
    • (2004) Nat Med , vol.10 , pp. 467-474
    • Olson, E.N.1
  • 9
    • 34547579291 scopus 로고    scopus 로고
    • MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure
    • Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, et al. (2007) MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation 116: 258-267.
    • (2007) Circulation , vol.116 , pp. 258-267
    • Thum, T.1    Galuppo, P.2    Wolf, C.3    Fiedler, J.4    Kneitz, S.5
  • 10
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • Heineke J, Molkentin JD, (2006) Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 7: 589-600.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 11
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden MS, Ghosh S, (2008) Shared principles in NF-kappaB signaling. Cell 132: 344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 12
    • 78650907445 scopus 로고    scopus 로고
    • A single NFkappaB system for both canonical and non-canonical signaling
    • Shih VF, Tsui R, Caldwell A, Hoffmann A, (2011) A single NFkappaB system for both canonical and non-canonical signaling. Cell Res 21: 86-102.
    • (2011) Cell Res , vol.21 , pp. 86-102
    • Shih, V.F.1    Tsui, R.2    Caldwell, A.3    Hoffmann, A.4
  • 14
    • 0037192342 scopus 로고    scopus 로고
    • Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy
    • Hirotani S, Otsu K, Nishida K, Higuchi Y, Morita T, et al. (2002) Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy. Circulation 105: 509-515.
    • (2002) Circulation , vol.105 , pp. 509-515
    • Hirotani, S.1    Otsu, K.2    Nishida, K.3    Higuchi, Y.4    Morita, T.5
  • 15
    • 0036487320 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species-mediated NF-kappa B activation in TNF-alpha-induced cardiomyocyte hypertrophy
    • Higuchi Y, Otsu K, Nishida K, Hirotani S, Nakayama H, et al. (2002) Involvement of reactive oxygen species-mediated NF-kappa B activation in TNF-alpha-induced cardiomyocyte hypertrophy. J Mol Cell Cardiol 34: 233-240.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 233-240
    • Higuchi, Y.1    Otsu, K.2    Nishida, K.3    Hirotani, S.4    Nakayama, H.5
  • 16
    • 84862809492 scopus 로고    scopus 로고
    • Interaction between NFkappaB and NFAT coordinates cardiac hypertrophy and pathological remodeling
    • Liu Q, Chen Y, Auger-Messier M, Molkentin JD, (2012) Interaction between NFkappaB and NFAT coordinates cardiac hypertrophy and pathological remodeling. Circ Res 110: 1077-1086.
    • (2012) Circ Res , vol.110 , pp. 1077-1086
    • Liu, Q.1    Chen, Y.2    Auger-Messier, M.3    Molkentin, J.D.4
  • 18
    • 67949112796 scopus 로고    scopus 로고
    • The I{kappa}B kinase {beta}/nuclear factor {kappa}B signaling pathway protects the heart from hemodynamic stress mediated by the regulation of manganese superoxide dismutase expression
    • Hikoso S, Yamaguchi O, Nakano Y, Takeda T, Omiya S, et al. (2009) The I{kappa}B kinase {beta}/nuclear factor {kappa}B signaling pathway protects the heart from hemodynamic stress mediated by the regulation of manganese superoxide dismutase expression. Circ Res 105: 70-79.
    • (2009) Circ Res , vol.105 , pp. 70-79
    • Hikoso, S.1    Yamaguchi, O.2    Nakano, Y.3    Takeda, T.4    Omiya, S.5
  • 19
    • 20444377621 scopus 로고    scopus 로고
    • Genomic structure and functional characterization of the promoter region of human IkappaB kinase-related kinase IKKi/IKKvarepsilon gene
    • Wang N, Ahmed S, Haqqi TM, (2005) Genomic structure and functional characterization of the promoter region of human IkappaB kinase-related kinase IKKi/IKKvarepsilon gene. Gene 353: 118-133.
    • (2005) Gene , vol.353 , pp. 118-133
    • Wang, N.1    Ahmed, S.2    Haqqi, T.M.3
  • 20
    • 78650328691 scopus 로고    scopus 로고
    • Novel splice variants of human IKKepsilon negatively regulate IKKepsilon-induced IRF3 and NF-kB activation
    • Koop A, Lepenies I, Braum O, Davarnia P, Scherer G, et al. (2011) Novel splice variants of human IKKepsilon negatively regulate IKKepsilon-induced IRF3 and NF-kB activation. Eur J Immunol 41: 224-234.
    • (2011) Eur J Immunol , vol.41 , pp. 224-234
    • Koop, A.1    Lepenies, I.2    Braum, O.3    Davarnia, P.4    Scherer, G.5
  • 21
    • 0038374178 scopus 로고    scopus 로고
    • IKKi/IKKepsilon plays a key role in integrating signals induced by pro-inflammatory stimuli
    • Kravchenko VV, Mathison JC, Schwamborn K, Mercurio F, Ulevitch RJ, (2003) IKKi/IKKepsilon plays a key role in integrating signals induced by pro-inflammatory stimuli. J Biol Chem 278: 26612-26619.
    • (2003) J Biol Chem , vol.278 , pp. 26612-26619
    • Kravchenko, V.V.1    Mathison, J.C.2    Schwamborn, K.3    Mercurio, F.4    Ulevitch, R.J.5
  • 22
    • 80755127110 scopus 로고    scopus 로고
    • IKKi: a novel regulator of Act1, IL-17 signaling and pulmonary inflammation
    • Shembade N, Harhaj EW, (2011) IKKi: a novel regulator of Act1, IL-17 signaling and pulmonary inflammation. Cell Mol Immunol 8: 447-449.
    • (2011) Cell Mol Immunol , vol.8 , pp. 447-449
    • Shembade, N.1    Harhaj, E.W.2
  • 23
    • 80052022606 scopus 로고    scopus 로고
    • The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation
    • Bulek K, Liu C, Swaidani S, Wang L, Page RC, et al. (2011) The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation. Nat Immunol 12: 844-852.
    • (2011) Nat Immunol , vol.12 , pp. 844-852
    • Bulek, K.1    Liu, C.2    Swaidani, S.3    Wang, L.4    Page, R.C.5
  • 24
    • 79955815187 scopus 로고    scopus 로고
    • IkappaB-Kinase-epsilon (IKKepsilon/IKKi/IkappaBKepsilon) expression and localization in prostate cancer tissues
    • Peant B, Forest V, Trudeau V, Latour M, Mes-Masson AM, et al. (2011) IkappaB-Kinase-epsilon (IKKepsilon/IKKi/IkappaBKepsilon) expression and localization in prostate cancer tissues. Prostate 71: 1131-1138.
    • (2011) Prostate , vol.71 , pp. 1131-1138
    • Peant, B.1    Forest, V.2    Trudeau, V.3    Latour, M.4    Mes-Masson, A.M.5
  • 25
    • 0038393016 scopus 로고    scopus 로고
    • IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
    • Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, et al. (2003) IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 4: 491-496.
    • (2003) Nat Immunol , vol.4 , pp. 491-496
    • Fitzgerald, K.A.1    McWhirter, S.M.2    Faia, K.L.3    Rowe, D.C.4    Latz, E.5
  • 26
    • 0033623848 scopus 로고    scopus 로고
    • IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex
    • Peters RT, Liao SM, Maniatis T, (2000) IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex. Mol Cell 5: 513-522.
    • (2000) Mol Cell , vol.5 , pp. 513-522
    • Peters, R.T.1    Liao, S.M.2    Maniatis, T.3
  • 27
    • 77956386624 scopus 로고    scopus 로고
    • Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload
    • Li H, He C, Feng J, Zhang Y, Tang Q, et al. (2010) Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload. Proc Natl Acad Sci U S A 107: 13818-13823.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13818-13823
    • Li, H.1    He, C.2    Feng, J.3    Zhang, Y.4    Tang, Q.5
  • 28
    • 3042802322 scopus 로고    scopus 로고
    • Malonyl-CoA decarboxylase (MCD) is differentially regulated in subcellular compartments by 5′AMP-activated protein kinase (AMPK). Studies using H9c2 cells overexpressing MCD and AMPK by adenoviral gene transfer technique
    • Sambandam N, Steinmetz M, Chu A, Altarejos JY, Dyck JR, et al. (2004) Malonyl-CoA decarboxylase (MCD) is differentially regulated in subcellular compartments by 5′AMP-activated protein kinase (AMPK). Studies using H9c2 cells overexpressing MCD and AMPK by adenoviral gene transfer technique. Eur J Biochem 271: 2831-2840.
    • (2004) Eur J Biochem , vol.271 , pp. 2831-2840
    • Sambandam, N.1    Steinmetz, M.2    Chu, A.3    Altarejos, J.Y.4    Dyck, J.R.5
  • 30
    • 80055033734 scopus 로고    scopus 로고
    • Activating transcription factor 3 deficiency promotes cardiac hypertrophy, dysfunction, and fibrosis induced by pressure overload
    • Zhou H, Shen DF, Bian ZY, Zong J, Deng W, et al. (2011) Activating transcription factor 3 deficiency promotes cardiac hypertrophy, dysfunction, and fibrosis induced by pressure overload. PLoS One 6: e26744.
    • (2011) PLoS One , vol.6
    • Zhou, H.1    Shen, D.F.2    Bian, Z.Y.3    Zong, J.4    Deng, W.5
  • 31
    • 80052877375 scopus 로고    scopus 로고
    • Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3beta and TGF-beta1-Smad signalling
    • Yan L, Wei X, Tang QZ, Feng J, Zhang Y, et al. (2011) Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3beta and TGF-beta1-Smad signalling. Cardiovasc Res 92: 85-94.
    • (2011) Cardiovasc Res , vol.92 , pp. 85-94
    • Yan, L.1    Wei, X.2    Tang, Q.Z.3    Feng, J.4    Zhang, Y.5
  • 32
    • 76549260937 scopus 로고    scopus 로고
    • Dehydroepiandrosterone-induced proliferation of prostatic epithelial cell is mediated by NFKB via PI3K/AKT signaling pathway
    • Sun HZ, Yang TW, Zang WJ, Wu SF, (2010) Dehydroepiandrosterone-induced proliferation of prostatic epithelial cell is mediated by NFKB via PI3K/AKT signaling pathway. J Endocrinol 204: 311-318.
    • (2010) J Endocrinol , vol.204 , pp. 311-318
    • Sun, H.Z.1    Yang, T.W.2    Zang, W.J.3    Wu, S.F.4
  • 33
    • 33644859066 scopus 로고    scopus 로고
    • Cardioprotection afforded by NF-kappaB ablation is associated with activation of Akt in mice overexpressing TNF-alpha
    • Higuchi Y, Chan TO, Brown MA, Zhang J, DeGeorge BJ, et al. (2006) Cardioprotection afforded by NF-kappaB ablation is associated with activation of Akt in mice overexpressing TNF-alpha. Am J Physiol Heart Circ Physiol 290: H590-H598.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Higuchi, Y.1    Chan, T.O.2    Brown, M.A.3    Zhang, J.4    DeGeorge, B.J.5
  • 34
    • 41549165085 scopus 로고    scopus 로고
    • Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?
    • Chau TL, Gioia R, Gatot JS, Patrascu F, Carpentier I, et al. (2008) Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated? Trends Biochem Sci 33: 171-180.
    • (2008) Trends Biochem Sci , vol.33 , pp. 171-180
    • Chau, T.L.1    Gioia, R.2    Gatot, J.S.3    Patrascu, F.4    Carpentier, I.5
  • 35
    • 79251542927 scopus 로고    scopus 로고
    • Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1
    • Joung SM, Park ZY, Rani S, Takeuchi O, Akira S, et al. (2011) Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1. J Immunol 186: 499-507.
    • (2011) J Immunol , vol.186 , pp. 499-507
    • Joung, S.M.1    Park, Z.Y.2    Rani, S.3    Takeuchi, O.4    Akira, S.5
  • 36
    • 0036950082 scopus 로고    scopus 로고
    • Gene expression in fibroblasts and fibrosis: involvement in cardiac hypertrophy
    • Manabe I, Shindo T, Nagai R, (2002) Gene expression in fibroblasts and fibrosis: involvement in cardiac hypertrophy. Circ Res 91: 1103-1113.
    • (2002) Circ Res , vol.91 , pp. 1103-1113
    • Manabe, I.1    Shindo, T.2    Nagai, R.3
  • 37
    • 84855451706 scopus 로고    scopus 로고
    • The antifibrotic agent pirfenidone inhibits angiotensin II-induced cardiac hypertrophy in mice
    • Yamazaki T, Yamashita N, Izumi Y, Nakamura Y, Shiota M, et al. (2012) The antifibrotic agent pirfenidone inhibits angiotensin II-induced cardiac hypertrophy in mice. Hypertens Res 35: 34-40.
    • (2012) Hypertens Res , vol.35 , pp. 34-40
    • Yamazaki, T.1    Yamashita, N.2    Izumi, Y.3    Nakamura, Y.4    Shiota, M.5
  • 38
    • 63849247206 scopus 로고    scopus 로고
    • Redox sensitive signaling pathways in cardiac remodeling, hypertrophy and failure
    • Anilkumar N, Sirker A, Shah AM, (2009) Redox sensitive signaling pathways in cardiac remodeling, hypertrophy and failure. Front Biosci 14: 3168-3187.
    • (2009) Front Biosci , vol.14 , pp. 3168-3187
    • Anilkumar, N.1    Sirker, A.2    Shah, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.