Benzo[α]pyrene repressed DNA mismatch repair in human breast cancer cells

Toxicology

Volumn 304, Issue , 2013, Pages 167-172

  Chen, Yuanhong ^a   Huang, Changjiang ^a   Bai, Chenglian ^a   Gao, Hui ^a   Ma, Ruihua ^a   Liu, Xiaojuan ^a   Dong, Qiaoxiang ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Benzo pyrene; DNA MMR; Q PCR; ZR75 1

Indexed keywords

BENZO[A]PYRENE;

ARTICLE; BREAST CANCER; CANCER CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GENE REPRESSION; HUMAN; HUMAN CELL; MISMATCH REPAIR; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; WESTERN BLOTTING;

BENZO(A)PYRENE; BLOTTING, WESTERN; BREAST NEOPLASMS; CARCINOGENS; CELL LINE, TUMOR; DNA MISMATCH REPAIR; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MUTAGENS;

EID: 84872779761     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.01.003     Document Type: Article

References (35)

1. Charles G.D., Bartels M.J., Zacharewski T.R., Gollapudi B.B., Freshour N.L., Carney E.W. Activity of benzo[a]pyrene and its hydroxylated metabolites in an estrogen receptor-alpha reporter gene assay. Toxicol. Sci. 2000, 55:320-326.
2. Clemons M., Goss P. Estrogen and the risk of breast cancer. N. Engl. J. Med. 2001, 344:276-285.
3. Cogliano V.J., Baan R.A., Straif K., Grosse Y., Secretan B., El Ghissassi F. Use of mechanistic data in IARC evaluations. Environ. Mol. Mutagen. 2008, 49:100-109. 10.1002/em.20370.
4. Eliassen A.H., Missmer S.A., Tworoger S.S., Spiegelman D., Barbieri R.L., Dowsett M., Hankinson S.E. Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women. J. Natl. Cancer Inst. 2006, 98:1406-1415.
5. Friedberg E.C. How nucleotide excision repair protects against cancer. Nat. Rev. Cancer 2001, 1:22-33.
6. Gu J., Horikawa Y., Chen M., Dinney C.P., Wu X. Benzo(α)pyrene diol epoxide-induced chromosome 9p21 aberrations are associated with increased risk of bladder cancer. Cancer Epidemiol. Biomarkers Prev. 2008, 17:2445-2450.
7. Harvey R.G. Polycyclic Aromatic Hydrocarbons: Chemistry and Carcinogenicity 1991, Cambridge University Press, New York.
8. Henkler F., Stolpmann K., Luch A. Exposure to polycyclic aromatic hydrocarbons: bulky DNA adducts and cellular responses. EXS 2012, 101:107-131.
9. Huovinen M. Effects of Benzo(α)pyrene in Human Breast Cancer Cell Lines Related to Chemical Carcinogenesis 2011, University of Eastern Finland, Kuopio.
10. IARC. Polynuclear Aromatic Compounds. Part 1. Chemical, Environmental and Experimental Data; IARC Monographs on the Evaluation of Carcinogenic Risks to Humans 1983, Lyon, France, IARC.
11. Irving J.A., Dupuis B., Wang L., Gilks C.B. Cyclical expression of the DNA mismatch repair enzyme hMLH1 in normal endometrium. Fertil. Steril. 2002, 78:195-196.
12. Iwahashi Y., Ito E., Yanagisawa Y., Akiyama Y., Yuasa Y., Onodera T., Maruyama K. Promoter analysis of the human mismatch repair gene hMSH2. Gene 1998, 213:141-147.
13. Jin P., Lu X.J., Sheng J.Q., Fu L., Meng X.M., Wang X., Shi T.P., Li S.R., Rao J. Estrogen stimulates the expression of mismatch repair gene hMLH1 in colonic epithelial cells. Cancer Prev. Res. 2010, 3:910-916.
14. Lei X., Zhu Y., Tomkinson A., Sun L. Measurement of DNA mismatch repair activity in live cells. Nucleic Acids Res. 2004, 32:e100.
15. Li D., Wang M., Dhingra K., Hittelman W.N. Aromatic DNA adducts in adjacent tissues of breast cancer patients: clues to breast cancer etiology. Cancer Res. 1996, 56:287-293.
16. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2-[Delta][Delta] CT method. Methods 2001, 25:402-408.
17. Lotsari J.E., Gylling A., Abdel-Rahman W.M., Nieminen T.T., Aittomaki K., Friman M., Pitkanen R., Aarnio M., Jarvinen H., Mecklin J.P. Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non-carriers, and sporadic cases. Breast Cancer Res. 2012, 14:R90.
18. Martin L., Coffey M., Lawler M., Hollywood D., Marignol L. DNA mismatch repair and the transition to hormone independence in breast and prostate cancer. Cancer Lett. 2010, 291:142-149.
19. Miyamoto T., Shiozawa T., Kashima H., Feng Y.Z., Suzuki A., Kurai M., Nikaido T., Konishi I. Estrogen up-regulates mismatch repair activity in normal and malignant endometrial glandular cells. Endocrinology 2006, 147:4863-4870.
20. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-63.
21. Pahlman R., Pelkonen O. Mutagenicity studies of different polycyclic aromatic hydrocarbons: the significance of enzymatic factors and molecular structure. Carcinogenesis 1987, 8:773-778.
22. Shi Q., Wang L.-E., Bondy M.L., Brewster A., Singletary S.E., Wei Q. Reduced DNA repair of benzo[a]pyrene diol epoxide-induced adducts and common XPD polymorphisms in breast cancer patients. Carcinogenesis 2004, 25:1695-1700.
23. Smith T.R., Liu-Mares W., Van Emburgh B.O., Levine E.A., Allen G.O., Hill J.W., Reis I.M., Kresty L.A., Pegram M.D., Miller M.S., Hu J.J. Genetic polymorphisms of multiple DNA repair pathways impact age at diagnosis and TP53 mutations in breast cancer. Carcinogenesis 2011, 32:1354-1360.
24. Spink B.C., Bennett J.A., Pentecost B.T., Lostritto N., Englert N.A., Benn G.K., Goodenough A.K., Turesky R.J., Spink D.C. Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells. Toxicol. Appl. Pharmacol. 2009, 240:355-366.
25. Tamimi R.M., Byrne C., Colditz G.A., Hankinson S.E. Endogenous hormone levels, mammographic density, and subsequent risk of breast cancer in postmenopausal women. J. Natl. Cancer Inst. 2007, 99:1178-1187.
26. Tian Q., Stepaniants S.B., Mao M., Weng L., Feetham M.C., Doyle M.J., Yi E.C., Dai H., Thorsson V., Eng J., Goodlett D., Berger J.P., Gunter B., Linseley P.S., Stoughton R.B., Aebersold R., Collins S.J., Hanlon W.A., Hood L.E. Integrated genomic and proteomic analyses of gene expression in mammalian cells. Mol. Cell. Proteomics 2004, 3:960-969.
27. Vanparys C., Maras M., Lenjou M., Robbens J., Van Bockstaele D., Blust R., De Coen W. Flow cytometric cell cycle analysis allows for rapid screening of estrogenicity in MCF-7 breast cancer cells. Toxicol. In Vitro 2006, 20:1238-1248.
28. Vasen H.F.A., Stormorken A., Menko F.H., Nagengast F.M., Kleibeuker J.H., Griffioen G., Taal B.G., Moller P., Wijnen J.T. MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families. J. Clin. Oncol. 2001, 19:4074-4080.
29. Wada-Hiraike O., Yano T., Nei T., Matsumoto Y., Nagasaka K., Takizawa S., Oishi H., Arimoto T., Nakagawa S., Yasugi T., Kato S., Taketani Y. The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor [alpha]. Br. J. Cancer 2005, 92:2286-2291.
30. Wu J., Gu L., Wang H., Geacintov N.E., Li G.-M. Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis. Mol. Cell. Biol. 1999, 19:8292-8301.
31. Xiong P., Bondy M.L., Li D., Shen H., Wang L.-E., Singletary S.E., Spitz M.R., Wei Q. Sensitivity to benzo(α)pyrene diol-epoxide associated with risk of breast cancer in young women and modulation by glutathione s-transferase polymorphisms. Cancer Res. 2001, 61:8465-8469.
32. Young L.C., Keuling A.M., Lai R., Nation P.N., Tron V.A., Andrew S.E. The associated contributions of p53 and the DNA mismatch repair protein Msh6 to spontaneous tumorigenesis. Carcinogenesis 2007, 28:2131-2138.
33. Zheng P.-Z., Wang K.-K., Zhang Q.-Y., Huang Q.-H., Du Y.-Z., Zhang Q.-H., Xiao D.-K., Shen S.-H., Imbeaud S., Eveno E., Zhao C.-J., Chen Y.-L., Fan H.-Y., Waxman S., Auffray C., Jin G., Chen S.-J., Chen Z., Zhang J. Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:7653-7658.
34. Zhou B., Dong Q., Ma R., Chen Y., Yang J., Sun L.-Z., Huang C. Rapid isolation of highly pure single-stranded DNA from phagemids. Anal. Biochem. 2009, 389:177-179.
35. Zhou B., Huang C., Yang J., Lu J., Dong Q., Sun L.-Z. Preparation of heteroduplex enhanced green fluorescent protein plasmid for in vivo mismatch repair activity assay. Anal. Biochem. 2009, 388:167-169.