Transcriptional regulatory factor X6 (RFX6) increases gastric inhibitory polypeptide (GIP) expression in enteroendocrine k-cells and is involved in GIP hypersecretion in high fat diet-induced obesity

Journal of Biological Chemistry

Volumn 288, Issue 3, 2013, Pages 1929-1938

  Suzuki, Kazuyo ^a   Harada, Norio ^a   Yamane, Shunsuke ^a   Nakamura, Yasuhiko ^a   Sasaki, Kazuki ^a   Nasteska, Daniela ^a   Joo, Erina ^a   Shibue, Kimitaka ^a   Harada, Takanari ^a   Hamasaki, Akihiro ^a   Toyoda, Kentaro ^a   Nagashima, Kazuaki ^a   Inagaki, Nobuya ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TISSUE; CELLULAR CONTENT; DIET-INDUCED OBESITY; ENERGY ACCUMULATION; ENHANCED GFP; EXPRESSION LEVELS; FLOW CYTOMETRY ANALYSIS; GENE ANALYSIS; GLUCOSE-STIMULATED INSULIN SECRETIONS; HIGH-FAT DIET; HYPERSECRETION; IN-VITRO; IN-VIVO; INSULIN SECRETION; INTESTINAL CELLS; INTESTINAL EPITHELIAL CELLS; MICROARRAY ANALYSIS; MOLECULAR MECHANISM; MRNA EXPRESSION; OBESE MICE; OVER-EXPRESSION; PROMOTER ACTIVITIES; REGULATORY FACTORS; SMALL INTESTINE;

ACTIVATION ANALYSIS; CELL CULTURE; FACTOR ANALYSIS; GLUCOSE; INSULIN; MAMMALS; NUTRITION; PHYSIOLOGY; TISSUE;

CELLS;

GASTRIC INHIBITORY POLYPEPTIDE; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; REGULATORY FACTOR X6; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL ISOLATION; CELL LEVEL; CONTROLLED STUDY; ENTEROENDOCRINE CELL; ENTEROENDOCRINE K CELL; FLOW CYTOMETRY; GENE EXPRESSION; GENE SILENCING; GIP GENE; HETEROZYGOTE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTESTINE CELL; KNOCKOUT MOUSE; LIPID DIET; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SECRETION; SMALL INTESTINE;

ADIPOSE TISSUE; ANIMALS; DIET, HIGH-FAT; DNA-BINDING PROTEINS; ENTEROENDOCRINE CELLS; GASTRIC INHIBITORY POLYPEPTIDE; GENE EXPRESSION; GENE KNOCK-IN TECHNIQUES; GENES, REPORTER; GLUCOSE; GREEN FLUORESCENT PROTEINS; INSULIN; INTESTINAL MUCOSA; MICE; MICE, TRANSGENIC; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRIMARY CELL CULTURE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

MUS;

EID: 84872727458     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.423137     Document Type: Article

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