Regulation of xylosyltransferase i gene expression by interleukin 1β in human primary chondrocyte cells: Mechanism and impact on proteoglycan synthesis

Journal of Biological Chemistry

Volumn 288, Issue 3, 2013, Pages 1774-1784

  Khair, Mostafa ^a   Bourhim, Mustapha ^a   Barré, Lydia ^a   Li, Dong ^a   Netter, Patrick ^a   Magdalou, Jacques ^a   Fournel Gigleux, Sylvie ^a   Ouzzine, Mohamed ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS PATHWAYS; CHAIN ASSEMBLIES; CHONDROCYTE CELLS; CHROMATIN IMMUNOPRECIPITATION ASSAY; CYTOKINES; DOWN-REGULATION; GLYCOSAMINOGLYCANS; INTERLEUKIN-1; KEY REGULATORS; MAJOR ELEMENTS; POINT MUTATIONS; PRIMARY CHONDROCYTES; PROMOTER ACTIVITIES; PROMOTER DELETIONS; PROTEOGLYCAN SYNTHESIS; PROTEOGLYCANS; RATE-LIMITING STEPS; RESPONSE ELEMENTS; SIGNALING PATHWAYS; TRANSACTIVATION; TRANSACTIVATORS; UNDERLYING MECHANISM; XYLOSYLTRANSFERASE I;

BIOCHEMISTRY; CARTILAGE; MODULATION; TISSUE;

GENE EXPRESSION;

INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEOGLYCAN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SP3; TRANSFERASE; UNCLASSIFIED DRUG; XYLOSYLTRANSFERASE 1;

AGED; ARTICLE; CARTILAGE CELL; CLINICAL ARTICLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DOWN REGULATION; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; KNEE OSTEOARTHRITIS; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEOGLYCAN SYNTHESIS; SIGNAL TRANSDUCTION; XT1 GENE;

AGED; BASE SEQUENCE; BINDING SITES; CARTILAGE; CHONDROCYTES; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1BETA; MAP KINASE KINASE 4; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PENTOSYLTRANSFERASES; PRIMARY CELL CULTURE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEOGLYCANS; SIGNAL TRANSDUCTION; SP3 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP-1;

EID: 84872722328     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.419887     Document Type: Article

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