Prolyl 4-hydroxlase activity is essential for development and cuticle formation in the human infective parasitic nematode brugia malayi

Journal of Biological Chemistry

Volumn 288, Issue 3, 2013, Pages 1750-1761

  Winter, Alan D ^a   McCormack, Gillian ^a   Myllyharju, Johanna ^b   Page, Antony P ^a,b  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF OULU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYPROLINES; BIOCHEMICAL ACTIVITY; BIOINFORMATIC ANALYSIS; BIOSYNTHETIC ENZYMES; CAENORHABDITIS ELEGANS; CO-EXPRESSION; COLLAGEN POLYPEPTIDES; COMPLEX FORMATIONS; CONTROL MECHANISM; COVALENT LINK; DERIVED MATERIALS; ELEGANS; ENZYMATIC ACTIVITIES; EXTRACELLULAR MATRICES; HETEROLOGOUS EXPRESSION; HUMAN ENZYMES; INSECT CELLS; NON-REDUCIBLE; OLIGOMERIC COMPLEXES; PARASITE; PARASITE CONTROL; PROLINE RESIDUES; PROTEIN DISULFIDE ISOMERASES; SEQUENCE DATABASE; TRIPLE HELIXES; UNIQUE FEATURES;

AMINO ACIDS; BIOINFORMATICS; COLLAGEN; OLIGOMERS;

ENZYME ACTIVITY;

PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; RECOMBINANT ENZYME;

ANIMAL CELL; ARTICLE; BIOINFORMATICS; BRUGIA MALAYI; CAENORHABDITIS ELEGANS; COMPLEX FORMATION; CONTROLLED STUDY; CUTICLE; ENZYME ACTIVITY; HETEROLOGOUS EXPRESSION; INSECT CELL; MUTANT; NONHUMAN; PARASITE DEVELOPMENT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA INTERFERENCE;

ANIMALS; BRUGIA MALAYI; CAENORHABDITIS ELEGANS; COLLAGEN; COMPUTATIONAL BIOLOGY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC COMPLEMENTATION TEST; HELMINTH PROTEINS; HUMANS; MUTATION; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN SUBUNITS; RNA, SMALL INTERFERING;

BRUGIA MALAYI; CAENORHABDITIS ELEGANS; EUKARYOTA; HEXAPODA;

EID: 84872713545     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.397604     Document Type: Article

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