Rapid analysis of residual palladium in pharmaceutical development using a catalysis-based fluorometric method

Organic Process Research and Development

Volumn 17, Issue 1, 2013, Pages 108-113

  Bu, Xiaodong ^a   Koide, Kazunori ^b   Carder, Evan J ^a   Welch, Christopher J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYLIC ETHERS; COMPLEX SAMPLES; DEALLYLATION; FLUORESCENCE ASSAY; FLUORESCENT PRODUCTS; FLUOROMETRIC METHOD; HIGH-THROUGHPUT APPROACHES; INDUCTIVELY COUPLED PLASMA-OPTICAL EMISSION SPECTROSCOPY; MANUFACTURING ENVIRONMENTS; PHARMACEUTICAL INTERMEDIATES; PHARMACEUTICAL PROCESS DEVELOPMENT; RAPID ANALYSIS; RESIDUAL METALS;

EMISSION SPECTROSCOPY; ETHERS; FLUORESCENCE; INDUCTIVELY COUPLED PLASMA; INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY; PILOT PLANTS; TURNAROUND TIME;

CATALYSIS;

EID: 84872698005     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op3003008     Document Type: Article

References (18)

1. Magano, J.; Dunetz, J. R. Chem. Rev. 2011, 111, 2177-2250
2. Welch, C. J.; Albaneze-Walker, J.; Leonard, W. R.; Biba, M.; DaSilva, J.; Henderson, D.; Laing, B.; Mathre, D. J.; Spencer, S.; Bu, Wang, T. Org. Process Res. Dev. 2005, 9, 198-205
3. Garrett, C. E.; Prasad, K. Adv. Synth. Catal. 2004, 346, 889-900
4. Li, B.; Buzon, R. A.; Zhang, Z. Org. Process Res. Dev. 2007, 11, 951-955
5. Bullock, K. M.; Mitchell, M. B.; Toczko, J. F. Org. Process Res. Dev. 2008, 12, 896-899
6. Huang, J. P.; Chen, X. X.; Gu, S. X.; Zhao, W. X.; Chen, F. E. Org. Process Res. Dev. 2010, 14, 939-941
7. Jiang, X. L.; Lee, G. T.; Villhauer, E. B.; Prasad, K.; Prasad, M. Org. Process Res. Dev. 2010, 14, 883-889
8. Reginato, G.; Sadler, P.; Wilkes, R. D. Org. Process Res. Dev. 2011, 15, 1396-1405
9. Wang, L.; Green, L.; Li, Z.; McCabe Dunn, J.; Bu; Welch, C. J.; Li, C.; Wang, T.; Tu, Q.; Bekos, E.; Richardson, D.; Eckert, J.; Cui, J. Org. Process Res. Dev. 2011, 15, 1371-1376
10. Welch, C. J.; Shaimi, M.; Biba, M.; Chilenski, J. R.; Szumigala, R. H.; Dolling, U.; Mathre, D. J.; Reider, P. J. J. Sep. Sci. 2002, 25, 847-850
11. Song, F. L.; Garner, A. L.; Koide, K. J. Am. Chem. Soc. 2007, 129, 12354-12355
12. Garner, A. L.; Koide, K. Chem. Commun. 2009, 86-88
13. Garner, A. L.; Song, F. L.; Koide, K. J. Am. Chem. Soc. 2009, 131, 5163-5171
14. Song, F. L.; Carder, E. J.; Kohler, C. C.; Koide, K. Chem.-Eur. J. 2010, 16, 13500-13508
15. Li, D.; Campbell, L. D.; Austin, B. A.; Koide, K. ChemPlusChem 2012, 77, 281-283
16. Inamoto, K.; Campbell, L. D.; Doi, T.; Koide, K. Tetrahedron Lett. 2012, 53, 3147-3148
17. Aqua Regia. In Laboratory Safety Manual; Princeton University: Princeton, NJ, http://web.princeton.edu/sites/ehs/labsafetymanual/cheminfo/aquaregia.htm.
18. Davies, I.; Welch, C. J. Science 2009, 325, 701-704