Optimization and scale-up of a suzuki#miyaura coupling reaction: Development of an efficient palladium removal technique

Organic Process Research and Development

Volumn 12, Issue 5, 2008, Pages 896-899

  Bullock, Kae M ^a   Mitchell, Mark B ^a   Toczko, Jennifer F ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 58149114899     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op800064y     Document Type: Article

References (16)

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16. Small-scale experiments demonstrated the reaction could be successfully run open to the atmosphere. For safety reasons, a nitrogen sweep was used on scale-up.