Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity

Journal of Virological Methods

Volumn 187, Issue 2, 2013, Pages 406-412

  Porta, Claudine ^b   Xu, Xiaodong ^a   Loureiro, Silvia ^a   Paramasivam, Saravanan ^c   Ren, Junyuan ^a   Al Khalil, Tara ^a   Burman, Alison ^b   Jackson, Terry ^b   Belsham, Graham J ^d   Curry, Stephen ^e   Lomonossoff, George P ^f   Parida, Satya ^b   Paton, David ^b   Li, Yanmin ^b   Wilsden, Ginette ^b   Ferris, Nigel ^b   Owens, Ray ^g   Kotecha, Abhay ^g   Fry, Elizabeth ^g   Stuart, David I ^g   Charleston, Bryan ^b   Jones, Ian M ^a   more..

^a UNIVERSITY OF READING   (United Kingdom)

^b INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^c INDIAN VETERINARY RESEARCH INSTITUTE   (India)

^d TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f JOHN INNES CENTRE   (United Kingdom)

^g UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

3C protease; Empty capsids; Foot and mouth disease virus; Frameshift; Protein processing; Recombinant baculovirus; Vaccine

Indexed keywords

3C PROTEASE; CELL PROTEIN; PROTEIN VP0; PROTEIN VP1; PROTEIN VP3; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA SEQUENCE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME REGULATION; FOOT AND MOUTH DISEASE VIRUS; INSECT CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SEQUENCE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; VIRUS CAPSID; VIRUS PARTICLE; VIRUS REPLICATION; WESTERN BLOTTING;

ANIMALS; BIOTECHNOLOGY; CAPSID; CELL LINE; CYSTEINE ENDOPEPTIDASES; DOWN-REGULATION; FOOT-AND-MOUTH DISEASE VIRUS; GENE EXPRESSION; INSECTS; TECHNOLOGY, PHARMACEUTICAL; VIRAL PROTEINS; VIRAL VACCINES;

ARTIODACTYLA; BOVINAE; FOOT-AND-MOUTH DISEASE VIRUS; HEXAPODA; MIRIDAE;

EID: 84872681669     PISSN: 01660934     EISSN: 18790984     Source Type: Journal    
DOI: 10.1016/j.jviromet.2012.11.011     Document Type: Article

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