Bronchodilator responsiveness using spirometry in healthy and asthmatic preschool children

Archives of Disease in Childhood

Volumn 98, Issue 2, 2013, Pages 112-117

  Borrego, Luis Miguel ^a,d   Stocks, Janet ^b   Almeida, Isabel ^a   Stanojevic, Sanja ^b,c   Antunes, João ^a   Leiria Pinto, Paula ^a   Rosado Pinto, José E ^a   Hoo, Ah Fong ^b  

^a HOSPITAL DONA ESTEFÂNIA   (Portugal)

^b Portex Respiratory Unit   (United Kingdom)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSIDADE NOVA DE LISBOA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

SALBUTAMOL; PLACEBO;

ARTICLE; ASTHMA; CHILD; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; FORCED EXPIRATORY FLOW; FORCED EXPIRATORY VOLUME; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL DEVICE; OUTPATIENT; PRESCHOOL CHILD; PRIORITY JOURNAL; REPRODUCIBILITY; SPIROMETRY; WHEEZING; CLINICAL ARTICLE; FORCED VITAL CAPACITY; LUNG FUNCTION; LUNG FUNCTION TEST;

ALBUTEROL; ASTHMA; BRONCHODILATOR AGENTS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FORCED EXPIRATORY VOLUME; HUMANS; PORTUGAL; REPRODUCIBILITY OF RESULTS; SPIROMETRY;

EID: 84872678205     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/archdischild-2012-301819     Document Type: Article

References (43)

1. Lai CK, Beasley R, Crane J, et al. Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax 2009;64:476-83.
2. Bush A. Practice imperfect-treatment for wheezing in preschoolers. N Engl J Med 2009;360:409-10.
3. Wildhaber JH, Hammer J. Asthma and wheezing disorders. In: Merkus P, Frey U, eds. Paediatric lung function. Sheffield, UK: European Respiratory Journals Ltd, 2010:209-24.
4. Bhatt JM, Smyth AR. The management of pre-school wheeze. Paediatr Respir Rev 2011;12:70-7.
5. Brand PL, Baraldi E, Bisgaard H, et al. Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J 2008;32:1096-110.
6. Chauliac ES, Silverman M, Zwahlen M, et al. The therapy of pre-school wheeze: appropriate and fair? Pediatr Pulmonol 2006;41:829-38. (Pubitemid 44300178)
7. Gappa M, Bush A. Pre-school wheeze: more questions than answers. Pediatr Pulmonol 2006;41:910-11. (Pubitemid 44534807)
8. Beydon N, Davis SD, Lombardi E, et al. An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool children. Am J Respir Crit Care Med 2007;175:1304-45. (Pubitemid 46905757)
9. Stocks J, Lum S. Pulmonary function tests in infants and preschool children. In: Wilmot RW, Boat TF, Bush A, et al., eds. Kendig's disorders of the respiratory tract in children. Philadelphia, USA: Elsevier, 2012:169-210.
10. Aurora P, Stocks J, Oliver C, et al. Quality control for spirometry in preschool children with and without lung disease. Am J Respir Crit Care Med 2004;169:1152-9. (Pubitemid 38624796)
11. Turner SW, Craig LC, Harbour PJ, et al. Spirometry in 5-year-olds - validation of current guidelines and the relation with asthma. Pediatr Pulmonol 2007;42:1144-51. (Pubitemid 350231864)
12. Vilozni D, Barak A, Efrati O, et al. The role of computer games in measuring spirometry in healthy and 'asthmatic' preschool children. Chest 2005;128:1146-55. (Pubitemid 41324389)
13. Stanojevic S, Wade A, Cole TJ, et al. Spirometry centile charts for young Caucasian children: the Asthma UK Collaborative Initiative. Am J Respir Crit Care Med 2009;180:547-52.
14. Galant SP, Morphew T, Amaro S, et al. Value of the bronchodilator response in assessing controller naive asthmatic children. J Pediatr 2007;151:457-62, 462.
15. Galant SP, Morphew T, Newcomb RL, et al. The relationship of the bronchodilator response phenotype to poor asthma control in children with normal spirometry. J Pediatr 2011;158:953-9.
16. Pellegrino R, Viegi G, Brusasco V, et al. Interpretative strategies for lung function tests. Eur Respir J 2005;26:948-68. (Pubitemid 41632054)
17. Pellegrino R, Antonelli A, Mondino M. Bronchodilator testing: an endless story. Eur Respir J 2010;35:952-4.
18. Beydon N, M'buila C, Bados A, et al. Interrupter resistance short-term repeatability and bronchodilator response in preschool children. Respir Med 2007;101:2482-7.
19. Dundas I, Chan EY, Bridge PD, et al. Diagnostic accuracy of bronchodilator responsiveness in wheezy children. Thorax 2005;60:13-16. (Pubitemid 40101011)
20. Stocks J. Clinical implications of pulmonary function testing in preschool children. Paediatr Respir Rev 2006;7(Suppl 1):S26-9. (Pubitemid 43906235)
21. Stocks J. Pulmonary function tests in infants and young children. In: Chernick V, Boat TF, Wilmott RW, et al., eds. Kendig's disorders of the respiratory tract in children. Philadelphia, PA, USA: Elsevier, 2006:129-67.
22. Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31:143-78.
23. Ind PW, Pride NB. Assessment of airway responses and the cough reflex. In: Hughes JMB, Pride NB, eds. Lung function tests: physiological principles and clinical applications. London: Harcourt Brace, 1999:220-32.
24. Stanojevic S, Wade A, Stocks J. Reference values for lung function: past, present and future. Eur Respir J 2010;36:12-19.
25. Cohen J. Statistical power analysis for the behavioural sciences. 2nd edn. Hillsdale, New Jersey: Erlbaum Associates, 1988.
26. Bland JM, Altman DJ. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1(8476):307-10. (Pubitemid 16134762)
27. Chinn S. Statistics in respiratory medicine. 2. Repeatability and method comparison. Thorax 1991;46:454-6.
28. Aurora P, Bush A, Gustafsson P, et al. Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis. Am J Respir Crit Care Med 2005;171:249-56.
29. Aurora P, Stanojevic S, Wade A, et al. Lung clearance index at 4 years predicts subsequent lung function in children with cystic fibrosis. Am J Respir Crit Care Med 2011;183:752-8.
30. Neve V, Edme JL, Devos P, et al. Spirometry in 3-5-year-old children with asthma. Pediatr Pulmonol 2006;41:735-43. (Pubitemid 44157356)
31. Olaguibel JM, Alvarez-Puebla MJ, Anda M, et al. Comparative analysis of the bronchodilator response measured by impulse oscillometry (IOS), spirometry and body plethysmography in asthmatic children. J Investig Allergol Clin Immunol 2005;15:102-6. (Pubitemid 41020170)
32. Piccioni P, Borraccino A, Forneris MP, et al. Reference values of forced expiratory volumes and pulmonary flows in 3-6 year children: a cross-sectional study. Respir Res 2007;8:14.
33. Marotta A, Klinnert MD, Price MR, et al. Impulse oscillometry provides an effective measure of lung dysfunction in 4-year-old children at risk for persistent asthma. J Allergy Clin Immunol 2003;112:317-22. (Pubitemid 36981371)
34. Beydon N. Assessment of bronchial responsiveness in preschool children. Paediatr Respir Rev 2006;7(Suppl 1):S23-5. (Pubitemid 43906234)
35. Calogero C, Parri N, Baccini A, et al. Respiratory impedance and bronchodilator response in healthy Italian preschool children. Pediatr Pulmonol 2010;45:1086-94.
36. Oostveen E, Dom S, Desager K, et al. Lung function and bronchodilator response in 4-year-old children with different wheezing phenotypes. Eur Respir J 2010;35:865-72.
37. Thamrin C, Gangell CL, Udomittipong K, et al. Assessment of bronchodilator responsiveness in preschool children using forced oscillations. Thorax 2007;62:814-19.
38. Vilozni D, Hakim F, Adler A, et al. Reduced vital capacity after methacholine challenge in early childhood - is it due to trapped air or loss of motivation. Respir Med 2009;103:109-16.
39. Chan EY, Bridge PD, Dundas I, et al. Repeatability of airway resistance measurements made using the interrupter technique. Thorax 2003;58:344-7. (Pubitemid 36411422)
40. Mele L, Sly PD, Calogero C, et al. Assessment and validation of bronchodilation using the interrupter technique in preschool children. Pediatr Pulmonol 2010;45:633-8.
41. Thamrin C, Gangell CL, Kusel MM, et al. Expression of bronchodilator response using forced oscillation technique measurements: absolute versus relative. Eur Respir J 2010;36:212.
42. Ministério da Saúde. Estudo de opinião: Medidas contra o tabagismo. In: da Saúde Ministério. eds. Direcção-Geral da Saúde. Lisboa, Portugal, 2010:1-47.
43. Borrego LM, Stocks J, Almeida I, et al. The role of specific airways resistance and spirometry in assessing bronchodilator responsiveness in preschool children with and without asthma (Abstract). Eur Respir J 2010;36:2617s.