A new cytotoxic quinolone alkaloid and a pentacyclic steroidal glycoside from the stem bark of Crataeva nurvala: Study of anti-proliferative and apoptosis inducing property

European Journal of Medicinal Chemistry

Volumn 60, Issue , 2013, Pages 490-496

  Sinha, Sadhna ^a   Mishra, Priyanka ^a   Amin, Hina ^b   Rah, Bilal ^b   Nayak, Debasis ^b   Goswami, Anindya ^b   Kumar, Naresh ^c   Vishwakarma, Ram ^b   Ghosal, Sabari ^a,c  

^a AMITY UNIVERSITY   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

4 Quinolones; Capparaceae; Crataeva nurvala; Cytotoxic activity; Steroidal glycoside

Indexed keywords

5,7 DIMETHOXY 3 PHENYL 1 ETHYL 1,4 DIHYDRO 4 QUINOLONE; 5,7 DIMETHOXY 3 PHENYL 1 METHYL 1,4 DIHYDRO 4 QUINOLINONE; 5,7 DIMETHOXY 3 PHENYL 1,4 DIHYDRO 4 QUINOLINONE; ALKALOID DERIVATIVE; CRATAENOSIDE; PLANT GLYCOSIDE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BARK; CARBON NUCLEAR MAGNETIC RESONANCE; COLONY FORMATION; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CRATAEVA NURVALA; DRUG CYTOTOXICITY; DRUG STRUCTURE; FEMALE; HUMAN; HUMAN CELL; MEDICINAL PLANT; PROTON NUCLEAR MAGNETIC RESONANCE;

ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CAPPARACEAE; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; MCF-7 CELLS; MOLECULAR STRUCTURE; PENTACYCLIC TRITERPENES; PLANT BARK; PLANT STEMS; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84872675832     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.12.017     Document Type: Article

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