-
1
-
-
79952232216
-
Global cancer statistics
-
A. Jemal, F. Bray, M.M. Center, J. Ferlay, E. Ward, and D. Forman Global cancer statistics CA: Cancer J Clin 61 2011 69 90
-
(2011)
CA: Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
3
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
R.W. Johnstone, A.A. Ruefli, and S.W. Lowe Apoptosis: a link between cancer genetics and chemotherapy Cell 108 2002 153 164
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
5
-
-
77954739712
-
Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent
-
Y. Geng, L. Kohli, B.J. Klocke, and K.A. Roth Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent Neuro-oncol 12 2010 473 481
-
(2010)
Neuro-oncol
, vol.12
, pp. 473-481
-
-
Geng, Y.1
Kohli, L.2
Klocke, B.J.3
Roth, K.A.4
-
6
-
-
66649116856
-
Chloroquine in glioblastoma - New horizons for an old drug
-
A. Munshi Chloroquine in glioblastoma - new horizons for an old drug Cancer 115 2009 2380 2383
-
(2009)
Cancer
, vol.115
, pp. 2380-2383
-
-
Munshi, A.1
-
7
-
-
23844478817
-
AF-2364 [1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide] is a potential male contraceptive: A review of recent data
-
C.Y. Cheng, D. Mruk, B. Silvestrini, M. Bonanomi, C.H. Wong, and M.K. Siu AF-2364 [1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide] is a potential male contraceptive: a review of recent data Contraception 72 2005 251 261
-
(2005)
Contraception
, vol.72
, pp. 251-261
-
-
Cheng, C.Y.1
Mruk, D.2
Silvestrini, B.3
Bonanomi, M.4
Wong, C.H.5
Siu, M.K.6
-
8
-
-
0034915521
-
Two new male contraceptives exert their effects by depleting germ cells prematurely from the testis
-
C.Y. Cheng, B. Silvestrini, J. Grima, M.Y. Mo, L.J. Zhu, and E. Johansson Two new male contraceptives exert their effects by depleting germ cells prematurely from the testis Biol Reprod 65 2001 449 461
-
(2001)
Biol Reprod
, vol.65
, pp. 449-461
-
-
Cheng, C.Y.1
Silvestrini, B.2
Grima, J.3
Mo, M.Y.4
Zhu, L.J.5
Johansson, E.6
-
10
-
-
59649084165
-
TGF-beta3 and TNFalpha perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: A new concept of BTB regulation during spermatogenesis
-
W. Xia, E.W. Wong, D.D. Mruk, and C.Y. Cheng TGF-beta3 and TNFalpha perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: a new concept of BTB regulation during spermatogenesis Dev Biol 327 2009 48 61
-
(2009)
Dev Biol
, vol.327
, pp. 48-61
-
-
Xia, W.1
Wong, E.W.2
Mruk, D.D.3
Cheng, C.Y.4
-
11
-
-
34247225991
-
C-type natriuretic peptide regulates blood-testis barrier dynamics in adult rat testes
-
W. Xia, D.D. Mruk, and C.Y. Cheng C-type natriuretic peptide regulates blood-testis barrier dynamics in adult rat testes Proc Natl Acad Sci USA 104 2007 3841 3846
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 3841-3846
-
-
Xia, W.1
Mruk, D.D.2
Cheng, C.Y.3
-
13
-
-
0037368877
-
Lonidamine: Efficacy and safety in clinical trials for the treatment of solid tumors
-
S. Di Cosimo, G. Ferretti, P. Papaldo, P. Carlini, A. Fabi, and F. Cognetti Lonidamine: efficacy and safety in clinical trials for the treatment of solid tumors Drugs Today (Barc) 39 2003 157 174
-
(2003)
Drugs Today (Barc)
, vol.39
, pp. 157-174
-
-
Di Cosimo, S.1
Ferretti, G.2
Papaldo, P.3
Carlini, P.4
Fabi, A.5
Cognetti, F.6
-
14
-
-
0033594404
-
Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore
-
L. Ravagnan, I. Marzo, P. Costantini, S.A. Susin, N. Zamzami, and P.X. Petit Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore Oncogene 18 1999 2537 2546
-
(1999)
Oncogene
, vol.18
, pp. 2537-2546
-
-
Ravagnan, L.1
Marzo, I.2
Costantini, P.3
Susin, S.A.4
Zamzami, N.5
Petit, P.X.6
-
15
-
-
0035877967
-
Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis
-
O. Sordet, C. Rebe, I. Leroy, J.M. Bruey, C. Garrido, and C. Miguet Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis Blood 97 2001 3931 3940
-
(2001)
Blood
, vol.97
, pp. 3931-3940
-
-
Sordet, O.1
Rebe, C.2
Leroy, I.3
Bruey, J.M.4
Garrido, C.5
Miguet, C.6
-
16
-
-
0038206442
-
Phase II study of lonidamine and diazepam in the treatment of recurrent glioblastoma multiforme
-
S. Oudard, A. Carpentier, E. Banu, F. Fauchon, D. Celerier, and M.F. Poupon Phase II study of lonidamine and diazepam in the treatment of recurrent glioblastoma multiforme J Neurooncol 63 2003 81 86
-
(2003)
J Neurooncol
, vol.63
, pp. 81-86
-
-
Oudard, S.1
Carpentier, A.2
Banu, E.3
Fauchon, F.4
Celerier, D.5
Poupon, M.F.6
-
17
-
-
34547866709
-
Endothelial progenitor cells as a new agent contributing to vascular repair
-
E. Miller-Kasprzak, and P.P. Jagodzinski Endothelial progenitor cells as a new agent contributing to vascular repair Arch Immunol Ther Exp (Warsz) 55 2007 247 259
-
(2007)
Arch Immunol Ther Exp (Warsz)
, vol.55
, pp. 247-259
-
-
Miller-Kasprzak, E.1
Jagodzinski, P.P.2
-
18
-
-
80053580456
-
The packaging of siRNA within the mesoporous structure of silica nanoparticles
-
X. Li, Q.R. Xie, J. Zhang, W. Xia, and H. Gu The packaging of siRNA within the mesoporous structure of silica nanoparticles Biomaterials 32 2011 9546 9556
-
(2011)
Biomaterials
, vol.32
, pp. 9546-9556
-
-
Li, X.1
Xie, Q.R.2
Zhang, J.3
Xia, W.4
Gu, H.5
-
19
-
-
67649399288
-
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission
-
R.K. Dagda, S.J. Cherra 3rd, S.M. Kulich, A. Tandon, D. Park, and C.T. Chu Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission J Biol Chem 284 2009 13843 13855
-
(2009)
J Biol Chem
, vol.284
, pp. 13843-13855
-
-
Dagda, R.K.1
Cherra III, S.J.2
Kulich, S.M.3
Tandon, A.4
Park, D.5
Chu, C.T.6
-
20
-
-
77957264938
-
Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo
-
L. Su, C.Y. Cheng, and D.D. Mruk Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo Int J Biochem Cell Biol 42 2010 1864 1875
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 1864-1875
-
-
Su, L.1
Cheng, C.Y.2
Mruk, D.D.3
-
22
-
-
0033791574
-
Control of apoptotic DNA degradation
-
K.F. Ferri, and G. Kroemer Control of apoptotic DNA degradation Nat Cell Biol 2 2000 E63 E64
-
(2000)
Nat Cell Biol
, vol.2
-
-
Ferri, K.F.1
Kroemer, G.2
-
23
-
-
34548207775
-
Mechanism of cell death caused by complex i defects in a rat dopaminergic cell line
-
M. Marella, B.B. Seo, A. Matsuno-Yagi, and T. Yagi Mechanism of cell death caused by complex I defects in a rat dopaminergic cell line J Biol Chem 282 2007 24146 24156
-
(2007)
J Biol Chem
, vol.282
, pp. 24146-24156
-
-
Marella, M.1
Seo, B.B.2
Matsuno-Yagi, A.3
Yagi, T.4
-
24
-
-
80255123508
-
Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation
-
E. Calvino, M.C. Estan, G.P. Simon, P. Sancho, C. Boyano-Adanez Mdel, and E. de Blas Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation Biochem Pharmacol 82 2011 1619 1629
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 1619-1629
-
-
Calvino, E.1
Estan, M.C.2
Simon, G.P.3
Sancho, P.4
Boyano-Adanez Mdel, C.5
De Blas, E.6
-
25
-
-
0037174915
-
Mitochondrial targeting drug lonidamine triggered apoptosis in doxorubicin-resistant HepG2 cells
-
Y.C. Li, K.P. Fung, T.T. Kwok, C.Y. Lee, Y.K. Suen, and S.K. Kong Mitochondrial targeting drug lonidamine triggered apoptosis in doxorubicin-resistant HepG2 cells Life Sci 71 2002 2729 2740
-
(2002)
Life Sci
, vol.71
, pp. 2729-2740
-
-
Li, Y.C.1
Fung, K.P.2
Kwok, T.T.3
Lee, C.Y.4
Suen, Y.K.5
Kong, S.K.6
-
26
-
-
0035891212
-
Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437
-
A.S. Belzacq, C. El Hamel, H.L. Vieira, I. Cohen, D. Haouzi, and D. Metivier Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437 Oncogene 20 2001 7579 7587
-
(2001)
Oncogene
, vol.20
, pp. 7579-7587
-
-
Belzacq, A.S.1
El Hamel, C.2
Vieira, H.L.3
Cohen, I.4
Haouzi, D.5
Metivier, D.6
-
27
-
-
33745274726
-
Mitochondria: Dynamic organelles in disease, aging, and development
-
D.C. Chan Mitochondria: dynamic organelles in disease, aging, and development Cell 125 2006 1241 1252
-
(2006)
Cell
, vol.125
, pp. 1241-1252
-
-
Chan, D.C.1
-
28
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
29
-
-
0024325795
-
The combined use of radiation therapy and lonidamine in the treatment of brain metastases
-
L.M. DeAngelis, V.E. Currie, J.H. Kim, G. Krol, M.A. O'Hehir, and F.M. Farag The combined use of radiation therapy and lonidamine in the treatment of brain metastases J Neurooncol 7 1989 241 247
-
(1989)
J Neurooncol
, vol.7
, pp. 241-247
-
-
Deangelis, L.M.1
Currie, V.E.2
Kim, J.H.3
Krol, G.4
O'Hehir, M.A.5
Farag, F.M.6
-
30
-
-
0020682326
-
Effects of lonidamine alone or combined with hyperthermia in some experimental cell and tumour systems
-
B. Silvestrini, G.M. Hahn, V. Cioli, and C. De Martino Effects of lonidamine alone or combined with hyperthermia in some experimental cell and tumour systems Br J Cancer 47 1983 221 231
-
(1983)
Br J Cancer
, vol.47
, pp. 221-231
-
-
Silvestrini, B.1
Hahn, G.M.2
Cioli, V.3
De Martino, C.4
-
31
-
-
77952074404
-
AF-2364 is a prospective spermicide candidate
-
H. Wang, X.X. Chen, L.R. Wang, Y.D. Mao, Z.M. Zhou, and J.H. Sha AF-2364 is a prospective spermicide candidate Asian J Androl 12 2010 322 335
-
(2010)
Asian J Androl
, vol.12
, pp. 322-335
-
-
Wang, H.1
Chen, X.X.2
Wang, L.R.3
Mao, Y.D.4
Zhou, Z.M.5
Sha, J.H.6
-
32
-
-
77952318310
-
Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: Final results of CALGB 90206
-
B.I. Rini, S. Halabi, J.E. Rosenberg, W.M. Stadler, D.A. Vaena, and L. Archer Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206 J Clin Oncol 28 2010 2137 2143
-
(2010)
J Clin Oncol
, vol.28
, pp. 2137-2143
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
Stadler, W.M.4
Vaena, D.A.5
Archer, L.6
-
33
-
-
0142058027
-
Addition of either lonidamine or granulocyte colony-stimulating factor does not improve survival in early breast cancer patients treated with high-dose epirubicin and cyclophosphamide
-
P. Papaldo, M. Lopez, E. Cortesi, E. Cammilluzzi, M. Antimi, and E. Terzoli Addition of either lonidamine or granulocyte colony-stimulating factor does not improve survival in early breast cancer patients treated with high-dose epirubicin and cyclophosphamide J Clin Oncol 21 2003 3462 3468
-
(2003)
J Clin Oncol
, vol.21
, pp. 3462-3468
-
-
Papaldo, P.1
Lopez, M.2
Cortesi, E.3
Cammilluzzi, E.4
Antimi, M.5
Terzoli, E.6
-
34
-
-
79955824328
-
A potential male contraceptive, exerts its effects locally in the seminiferous epithelium of mammalian testes
-
K.W. Mok, D.D. Mruk, P.P. Lie, W.Y. Lui, and Cheng C.Y. Adjudin a potential male contraceptive, exerts its effects locally in the seminiferous epithelium of mammalian testes Reproduction 141 2011 571 580
-
(2011)
Reproduction
, vol.141
, pp. 571-580
-
-
Mok, K.W.1
Mruk, D.D.2
Lie, P.P.3
Lui, W.Y.4
Adjudin, C.C.Y.5
-
35
-
-
83755178073
-
A study to assess the assembly of a functional blood-testis barrier in developing rat testes
-
K.W. Mok, D.D. Mruk, W.M. Lee, and C.Y. Cheng A study to assess the assembly of a functional blood-testis barrier in developing rat testes Spermatogenesis 1 2011 270 280
-
(2011)
Spermatogenesis
, vol.1
, pp. 270-280
-
-
Mok, K.W.1
Mruk, D.D.2
Lee, W.M.3
Cheng, C.Y.4
-
36
-
-
33645657886
-
The vascular targeting property of paclitaxel is enhanced by SU6668, a receptor tyrosine kinase inhibitor, causing apoptosis of endothelial cells and inhibition of angiogenesis
-
E. Naumova, P. Ubezio, A. Garofalo, P. Borsotti, L. Cassis, and E. Riccardi The vascular targeting property of paclitaxel is enhanced by SU6668, a receptor tyrosine kinase inhibitor, causing apoptosis of endothelial cells and inhibition of angiogenesis Clin Cancer Res 12 2006 1839 1849
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1839-1849
-
-
Naumova, E.1
Ubezio, P.2
Garofalo, A.3
Borsotti, P.4
Cassis, L.5
Riccardi, E.6
-
37
-
-
84862504617
-
Delivering hydrophilic and hydrophobic chemotherapeutics simultaneously by magnetic mesoporous silica nanoparticles to inhibit cancer cells
-
Q. Liu, J. Zhang, W. Sun, Q.R. Xie, W. Xia, and H. Gu Delivering hydrophilic and hydrophobic chemotherapeutics simultaneously by magnetic mesoporous silica nanoparticles to inhibit cancer cells Int J Nanomed 7 2012 999 1013
-
(2012)
Int J Nanomed
, vol.7
, pp. 999-1013
-
-
Liu, Q.1
Zhang, J.2
Sun, W.3
Xie, Q.R.4
Xia, W.5
Gu, H.6
|