A novel population balance model to investigate the kinetics of in vitro cell proliferation: Part I model development

Biotechnology and Bioengineering

Volumn 109, Issue 3, 2012, Pages 772-781

  Fadda, Sarah ^a   Cincotti, Alberto ^a   Cao, Giacomo ^a,b  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b CENTER FOR ADVANCED STUDIES   (Italy)

Author keywords

Cell size; DNA content; Kinetics; Microgravity; Population balance; Proliferation

Indexed keywords

ADHERENT CELLS; ADJUSTABLE PARAMETERS; CELL CULTIVATION; CELL CYCLE; CELL NUMBER; CELL SIZE; CELL VOLUME; CELL-CYCLE PROGRESSION; DNA CONTENT; IN-LINE; IN-VITRO; INTRINSIC KINETICS; MATHEMATICAL EXPRESSIONS; MICROGRAVITY CONDITIONS; MITOTIC CYCLES; MODEL DEVELOPMENT; NUMERICAL SOLUTION; PETRI DISH; POPULATION BALANCE MODELS; POPULATION BALANCES; PROLIFERATION; QUANTITATIVE MEASUREMENT; RELIABLE MODELS; SINGLE PHASE; SUB-POPULATIONS; TRANSITION RATES;

CELL CULTURE; CELL PROLIFERATION; CELLS; DNA; ENZYME KINETICS; KINETICS; MICROGRAVITY; MICROGRAVITY PROCESSING; UNCERTAINTY ANALYSIS;

MATHEMATICAL MODELS;

ARTICLE; BIOLOGICAL MODEL; CELL CULTURE; CELL CYCLE CHECKPOINT; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL GROWTH; CELL KINETICS; CELL POPULATION; CELL PROLIFERATION; CELL VOLUME; CONTACT INHIBITION; DNA CONTENT; IN VITRO STUDY; MATHEMATICAL MODEL; POPULATION BALANCE MODEL;

BIOTECHNOLOGY; CELL ADHESION; CELL COUNT; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SIZE; DNA; HUMANS; MODELS, THEORETICAL;

EID: 84855932783     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24351     Document Type: Article

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