CLA-enriched milk powder reverses hypercholesterolemic risk factors in hamsters

Food Research International

Volumn 51, Issue 1, 2013, Pages 244-249

  Rodríguez Alcalá, Luis Miguel ^a   Fontecha, Javier ^a   de la Hoz, Lucia ^b   da Silva, Vera Sonia Nunes ^b   Carvalho, João Ernesto ^c   Pacheco, Maria Teresa Bertoldo ^b  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b INSTITUTO DE TECNOLOGIA DE ALIMENTOS   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Conjugated linoleic acid; Dyslipidemia; Hamsters; Hypercholesterolemic; Lipid profile; Liver enzymes

Indexed keywords

CONJUGATED LINOLEIC ACID; DYSLIPIDEMIAS; HAMSTERS; HYPERCHOLESTEROLEMIC; LIPID PROFILE;

ANTHROPOMETRY; BIOACTIVITY; DISEASES; ENZYMES; GLUCOSE; ISOMERS; LINOLEIC ACID; PHYSIOLOGICAL MODELS; WEIGHT CONTROL;

NUTRITION;

ANIMALIA; CRICETINAE; MESOCRICETUS AURATUS;

EID: 84872668716     PISSN: 09639969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodres.2012.12.013     Document Type: Article

References (36)

1. Akahoshi A., Koba K., Ichinose F., Kaneko M., Shimoda A., Nonaka K., et al. Dietary protein modulates the effect of CLA on lipid metabolism in rats. Lipids 2004, 39:25-30.
2. Benjamin S., Spener F. Conjugated linoleic acids as functional food: An insight into their health benefits. Nutrition and Metabolism 2009, 6:36. (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754987/ (Accessed Oct 08 2012)). 10.1186/1743-7075-6-36.
3. Bissonauth V., Chouinard Y., Marin J., Leblanc N., Richard D., Jacques H. The effects of t10, c12 CLA isomer compared with c9, t11 CLA isomeron lipid metabolism and body composition in hamsters. The Journal of Nutritional Biochemistry 2006, 17:597-603.
4. Brouwer I.A., Wanders A.J., Katan M.B. Effect of animal and industrial trans fatty acids on HDL and LDL cholesterol levels in humans - A quantitative review. PloS One 2010, 5(3):e9434. (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0009 434 (last access october 08 2012)). 10.1371/journal.pone.0009434.
5. Chardigny J.M., Destaillats F., Malpuech-Brugére C., Moulin J., Bauman D.E., Lock A.L., et al. Do trans fatty acids from industrially produced sources and from natural sources have the same effect on cardiovascular disease risk factors in healthy subjects? Results of the trans Fatty Acids Collaboration (TRANSFACT) study. American Journal of Clinical Nutrition 2008, 87:558-566.
6. de Deckere E.A.M., van Amelsvoort J.M.M., McNeill G.P., Jones P. Effects of conjugated linoleic acid (CLA) isomers on lipid levels and peroxisome proliferation in the hamster. British Journal of Nutrition 1999, 82:309-317.
7. Eder K., Ringseis R. Metabolism and actions of conjugated linoleic acids on atherosclerosis-related events in vascular endothelial cells and smooth muscle cells. Molecular Nutrition & Food Research 2010, 54:17-36.
8. Folch J., Lees M., Stanley G.H.S. A simple method for the isolation and purification of total lipids from animal tissues. The Journal of Biologycal Chemistry 1957, 226:497-509.
9. Fritsche J., Rickert R., Steinhart H., Yurawecz M.P., Mossoba M.M., Sehat N., et al. Conjugated linoleic acid (CLA) isomers: Formation, analysis, amounts in foods, and dietary intake. European Journal of Lipid Science and Technology 1999, 101(8):272-276.
10. Gavino V.C., Gavino G., Leblanc M.-J., Tuchweber B. An isomeric mixture of conjugated linoleic acids but not pure cis-9, trans-11-octadecadienoic acid affects body weight gain and plasma lipids in hamsters. Journal of Nutrition 2000, 130:27-29.
11. Golay P.A., Dionisi F., Hug B., Giuffrida F., Destaillats F. Direct quantification of fatty acids in dairy powders with special emphasis on transfatty acid content. Food Chemistry 2007, 101:1115-1120.
12. Gonçalves D.C., Lira F.S., Carnevali L.C., Rosa J.C., Pimentel G.D., Seelaender M. Conjugated linoleic acid: Good or bad nutrient. Diabetology and Metabolic Syndrome 2010, 2:62. http://www.dmsjournal.com/content/2/1/62 (last access Oct 08 2012). 10.1186/1758-5996-2-62.
13. Ip C., Singh M., Thompson H.J., Scimeca J.A. Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat. Cancer Research 1994, 54:1212-1215.
14. ISO IS Milk and milk products - Extraction methods for lipids and liposoluble compounds. ISO 14156-IDF 172:2001 2001.
15. ISO IS Milk fat - Preparation of fatty acid methyl esters. ISO 15884-IDF:182:2002 2002.
16. Jacome-Sosa M.M., Jing L., Ye W., Ruth M., Wright D.C., Reaney M.J., et al. Increased hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid in combination with trans-11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR:LA-cp rat. Nutrition and Metabolism 2010, 7:60. (http://www.nutritionandmetabolism.com/content/7/1/60 (last access October 2012)). 10.1186/1743-7075-7-60.
17. Lock A.L., Horne C.A.M., Bauman D.E., Salter A.M. Butter naturally enriched in conjugated linoleic acid and vaccenic acid alters tissue fatty acids and improves the plasma lipoprotein profile in cholesterol-fed hamsters. Journal of Nutrition 2005, 135:1934-1939.
18. Ma D.W.L., Wierzbicki A.A., Field C.J., Clandinin M.T. Preparation of conjugated linoleic acid from safflower oil. Journal of American Oil Chemist Society 1999, 76:729-730.
19. Marineli R.S., Marques A.C., Furlan C.P.B., Maróstica M.R. Antioxidant effects of the combination of conjugated linoleic acid and phytosterol supplementation in Sprague-Dawley rats. Food Research International 2012, 49:487-493.
20. a ed.), São Paulo, Michalany Ltda.
21. Nakamura Y.K., Flintoff-Dye N., Omaye S.T. Conjugated linoleic acid modulation of risk factors associated with atherosclerosis. Nutrition and Metabolism 2008, 5:22. (http://www.nutritionandmetabolism.com/content/5/1/22). 10.1186/1743-7075-5-22.
22. O'Shea M., Bassaganya-Riera J., Mohede I.C.M. Immunomodulatory properties of conjugated linoleic acid. American Journal of Clinical Nutrition 2004, 79:1199S-1206S. (Suppl.).
23. Park Y. Conjugated linoleic acid (CLA): Good or bad trans fat?. Journal of Food Composition and Analysis 2009, 22:S4-S24. (Suppl.).
24. Park Y., Pariza M.W. Mechanisms of body fat modulation by conjugated linoleic acid (CLA). Food Research International 2007, 40:311-323.
25. Ramos R., Mascarenhas J., Duarte P., Vicente C., Casteleiro C. Conjugated linoleic acid-induced toxic hepatitis: First case report. Digestive Diseases and Science 2009, 54:1141-1143.
26. Reeves P.G., Rossow K.L., Lindlauf J. Development and testing of the AIN-93 purified diets for rodents: Results on growth, kidney calcification and bone mineralization in rats and mice. Journal of Nutrition 1993, 123:1923-1931.
27. Ribot J., Portillo M.P., Pico C., Macarulla M.T., Palou A. Effects of trans-10, cis-12 conjugated linoleic acid on the expression of uncoupling proteins in hamsters fed an atherogenic diet. British Journal of Nutrition 2007, 97:1074-1082.
28. Rodríguez-Alcalá L.M., Fontecha J. Hot topic: Fatty acid and conjugated linoleic acid (CLA) isomer composition of commercial CLA-fortified dairy products: Evaluation after processing and storage. Journal of Dairy Science 2007, 90:2083-2090.
29. Scher J., Pronczuk A., Hajri T., Hayes K.C. Dietary conjugated linoleic acid lowers plasma cholesterol during cholesterol supplementation, but accentuates the atherogenic lipid profile during the acute phase response in hamsters. Journal of Nutrition 2003, 133:456-460.
30. Schmarr H.-G., Gross H.B., Shibamoto T. Analysis of polar cholesterol oxidation products: Evaluation of a new method involving transesterification, solid phase extraction, and gas chromatography. Journal of Agricultural and Food Chemistry 1996, 44:512-517.
31. Schmid A., Collomb M., Sieber R., Bee G. Conjugated linoleic acid in meat and meat products: A review. Meat Science 2006, 73:29-41.
32. Shiraishi R., Iwakiri R., Fujise T., Kuroki T., Kakimoto T., Takashima T., et al. Conjugated linoleic acid suppresses colon carcinogenesis in azoxymethane-pretreated rats with long-term feeding of diet containing beef tallow. Journal of Gastroenterology 2010, 45:625-635.
33. Silveira M.B., Carraro R., Monereo S., Tébar J. Conjugated linoleic acid (CLA) and obesity. Public Health Nutrition 2007, 10:1181-1186.
34. Tarling E.J., Ryan K.J.P., Bennett A.J., Salter A.M. Effect of dietary conjugated linoleic acid isomers on lipid metabolism in hamsters fed high carbohydrate and high-fat diets. British Journal of Nutrition 2009, 101:1630-1638.
35. Wahle K.W.J., Heys S.D., Rotondo D. Conjugated linoleic acids: Are they beneficial or detrimental to health?. Progress in Lipid Research 2004, 43:553-587.
36. Zabala A., Fernandez-Quintela A., Macarulla M.T., Simon E., Rodriguez V.M., Simon E., et al. Effects of conjugated linoleic acid on skeletal muscle triacylglycerol metabolism in hamsters. Nutrition 2006, 22:528-533.