Human Papillomavirus Up-Regulates MMP-2 and MMP-9 Expression and Activity by Inducing Interleukin-8 in Lung Adenocarcinomas

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Shiau, Ming Yuh ^a   Fan, Li Ching ^b   Yang, Shun Chun ^b   Tsao, Chang Hui ^c   Lee, Huei ^d   Cheng, Ya Wen ^d   Lai, Li Chuan ^b   Chang, Yih Hsin ^e  

^a HUNGKUANG UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; INTERLEUKIN 8; PROTEIN E6;

ANGIOGENESIS; ARTICLE; CANCER CELL; CANCER GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; LUNG ADENOCARCINOMA; METASTASIS; PAPILLOMAVIRUS INFECTION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ADENOCARCINOMA; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMAN PAPILLOMAVIRUS 16; HUMANS; INTERLEUKIN-8; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PAPILLOMAVIRUS INFECTIONS; UP-REGULATION;

HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 16;

EID: 84872665143     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054423     Document Type: Article

References (47)

1. Shijubo N, Kojima H, Nagata M, Ohchi T, Suzuki A, et al. (2003) Tumor angiogenesis of non-small cell lung cancer. Microsc Res Tech 60: 186-198.
2. Herbst RS, Onn A, Sandler A, (2005) Angiogenesis and lung cancer: prognostic and therapeutic implications. J Clin Oncol 23: 3243-3256.
3. Folkman J, Cotran R, (1976) Relation of vascular proliferation to tumor growth. Int Rev Exp Pathol 16: 207.
4. Hanahan D, Folkman J, (1996) Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364.
5. D'Amico TA, (2004) Angiogenesis in non-small cell lung cancer. Semin Thorac Cardiovasc Surg 16: 13-18.
6. Cheng YW, Chiou HL, Sheu GT, Hsieh LL, Chen JT, et al. (2001) The association of human papillomavirus 16/18 infection with lung cancer among nonsmoking Taiwanese women. Cancer Res 61: 2799-2803.
7. Cheng YW, Wu MF, Wang J, Yeh KT, Goan YG, et al. (2007) Human papillomavirus 16/18 E6 oncoprotein is expressed in lung cancer and related with p53 inactivation. Cancer Res 67: 10686-10693.
8. Cheng YW, Lee H, Shiau MY, Wu TC, Huang TT, et al. (2008) Human papillomavirus type 16/18 up-regulates the expression of interleukin-6 and antiapoptotic Mcl-1 in non-small cell lung cancer. Clin Cancer Res 14: 4705-4712.
9. Chang YH, Yu CW, Lai LC, Tsao CH, Ho KT, et al. (2010) Up-regulation of interleukin-17 expression by human papillomavirus type 16 E6 in nonsmall cell lung cancer. Cancer 116: 4800-4809.
10. Numasaki M, Fukushi J, Ono M, Narula SK, Zavodny PJ, et al. (2003) Interleukin-17 promotes angiogenesis and tumor growth. Blood 101: 2620-2627.
11. Smith DR, Polverini PJ, Kunkel SJ, Orringer MB, Whyte RI, et al. (1994) Inhibition of IL-8 attenuates angiogenesis in bronchogenic carcinoma. J Exp Med 179: 1409-1415.
12. Singh RK, Gutman M, Radinsky R, Bucana CD, Fidler IJ, (1994) Expression of interleukin-8 correlates with the metastatic potential of human melanoma cells in nude mice. Cancer Res 54: 3242-3248.
13. Ueda T, Shimada E, Urikawa T, (1994) Serum levels of cytokines in patients with colorectal cancer: possible involvement of interleukin-6 and interleukin-8 in hematogenous metastasis. J Gastroenterol 29: 423-429.
14. Luca M, Huang S, Gershenwald JE, Singh RK, Reich R, et al. (1997) Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis. Am J Pathol 151: 1105-1113.
15. Bequet-Romero M, Lopez-Ocejo O, (2000) Angiogenesis modulators expression in culture cell lines positives for HPV-16 oncoproteins. Biochem Biophys Res Commun 277: 55-61.
16. Masuya D, Huang C, Liu D, Kameyama K, Hayashi E, et al. (2001) The intratumoral expression of vascular endothelial growth factor and interleukin-8 associated with angiogenesis in nonsmall cell lung carcinoma patients. Cancer 92: 2628-2638.
17. Orditura M, De Vita F, Catalano G, Infusino S, Lieto E, et al. (2002) Elevated serum levels of interleukin-8 in advanced non-small cell lung cancer patients: relationship with prognosis. J Interferon Cytokine Res 22: 1129-1135.
18. Chen JJ, Yao PL, Yuan A, Hong TM, Shun CT, et al. (2003) Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer. Clin Cancer Res 9: 729-737.
19. Arenberg DA, Kunkel SL, Polverini PJ, Glass M, Burdick MD, et al. (1996) Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice. J Clin Invest 97: 2792-2802.
20. Wang J, Huang M, Lee P, Komanduri K, Sharma S, et al. (1996) Interleukin-8 inhibits non-small cell lung cancer proliferation: a possible role for regulation of tumor growth by autocrine and paracrine pathways. J Interferon Cytokine Res 16: 53-60.
21. Yuan A, Yang PC, Yu CJ, Chen WJ, Lin FY, et al. (2000) Interleukin-8 messenger ribonucleic acid expression correlates with tumor progression, tumor angiogenesis, patient survival, and timing of relapse in non-small-cell lung cancer. Am J Respir Crit Care Med 162: 1957-1963.
22. Inoue K, Slaton JW, Eve BY, Kim SJ, Perrotte P, et al. (2000) Interleukin 8 expression regulates tumorigenicity and metastases in androgen-independent prostate cancer. Clin Cancer Res 6: 2104-2119.
23. Li A, Dubey S, Varney ML, Dave BJ, Singh RK, (2003) IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J Immunol 170: 3369-3376.
24. Peng PL, Hsieh YA, Wang CJ, Hsu JL, Chou FP, (2006) Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2. Toxicol Appl Pharm 214: 8-15.
25. Alberg AJ, Samet JM, (2003) Epidemiology of lung cancer. Chest 123: 21S-49S.
26. Pillai MR, Nair MK, (2000) Development of a condemned mucosa syndrome and pathogenesis of human papillomavirus-associated upper aerodigestive tract and uterine cervical tumors. Exp Mol Pathol 69: 233-241.
27. Garzetti GG, Ciavattini A, Lucarini G, (1998) The role of human papillomavirus DNAs in cervical carcinoma and risk of lymph node metastasis: Association with 72-kilodalton metalloproteinase immunostaining. Cancer 82: 886-892.
28. Evander M, Frazer IH, Payne E, (1997) Identification of the alpha (6) integrin as a candidate receptor for papillomaviruses. J Virol 71: 2449-2456.
29. Tjalma WA, Weyler JJ, Bogers JJ, Pollefliet C, Baay M, et al. (2001) The importance of biological factors (bcl-2, bax, p53, PCNA, MI, HPV and angiogenesis) in invasive cervical cancer. Eur J Obstet Gynecol Reprod Biol 97: 223-230.
30. Toussaint-Smith E, Donner DB, Roman A, (2004) Expression of human papillomavirus type 16 E6 and E7 oncoproteins in primary foreskin keratinocytes is sufficient to alter the expression of angiogenic factors. Oncogene 23: 2988-2995.
31. Smola-Hess S, Pahne J, Mauch C, Zigrino P, Smola H, et al. (2005) Expression of membrane type 1 matrix metalloproteinase in papillomavirus-positive cells: role of the human papillomavirus (HPV) 16 and HPV8 E7 gene products. J Gen Virol 86: 1291-1296.
32. Lopez-Ocejo O, Viloria-Petit AM, Bequet-Romero M, Rak J, Mukhopadhyay D, et al. (2000) Oncogenes and tumor angiogenesis: The HPV-16 E6 oncoprotein activate the vascular endothelial growth factor (VEGF) gen promoter in a p53 independent manner. Oncogene 19: 4611-4620.
33. Zhu YM, Webster SJ, Flower D, Woll PJ, (2004) Interleukin-8/CXCL8 is a growth factor for human lung cancer cells. Br J Cancer 91: 1970-1976.
34. Salcedo R, Ponce ML, Young HA, Wasserman K, Ward JM, et al. (2000) Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood 96: 34-40.
35. Singh RK, Varney ML, Ino K, Vose JM, Bierman PJ, et al. (2000) Immune dysfunction despite high levels of immunoregulatory cytokine gene expression in autologous peripheral blood stem cell transplanted non-Hodgkin's lymphoma patients. Exp Hematol 28: 499-507.
36. Mian BM, Dinney CP, Bermejo CE, Sweeney P, Tellez C, et al. (2003) Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB. Clin Cancer Res 9: 3167-3175.
37. Atkinson JJ, Senior RM, (2003) Matrix metalloproteinase-9 in lung remodeling. Am J Respir Cell Mol Biol 28: 12-24.
38. Van den Steen PE, Proost P, Wuyts A, Van Damme J, Opdenakker G, (2000) Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-alpha and leaves RANTES and MCP-2 intact. Blood 96: 2673-2681.
39. Mulayim N, Savlu A, Guzeloglu-Kayisli O, Kayisli UA, Arici A, (2004) Regulation of endometrial stromal cell matrix metalloproteinase activity and invasiveness by interleukin-8. Fertil Steril 81: 904-911.
40. Huang SM, McCance DJ, (2002) Down regulation of the interleukin-8 promoter by human papillomavirus type 16 E6 and E7 through effects on CREB binding protein/p300 and P/CAF. J Virol 76: 8710-8721.
41. Li G, He L, Zhang E, Shi J, Zhang Q, et al. (2011) Overexpression of human papillomavirus (HPV) type 16 oncoproteins promotes angiogenesis via enhancing HIF-1a and VEGF expression in non-small cell lung cancer cells. Cancer Lett 311: 160-170.
42. Nor JE, Christensen J, Liu J, Peters M, Mooney DJ, et al. (2001) Up-regulation of Bcl-2 in microvascular endothelial cells enhances intratumoral angiogenesis and accelerates tumor growth. Cancer Res 61: 2183-2188.
43. Moulding DA, Quayle JA, Hart CA, Edwards SW, (1998) Mcl-1 expression in human neutrophils: regulation by cytokines and correlation with cell survival. Blood 92: 2495-2502.
44. Leuenroth SJ, Grutkoski PS, Ayala A, Simms HH, (2000) The loss of Mcl-1 expression in human polymorphonuclear leukocytes promotes apoptosis. J Leuko Biol 68: 158-166.
45. Hu M, Miller EJ, Lin X, Simms HH, (2004) Transmigration across a lung epithelial monolayer delays apoptosis of polymorphonuclear leukocytes. Surgery 135: 87-98.
46. Linden LM, (2002) IL-17 as a potential target for modulating airway neutrophilia. Curr Pharm Des 8: 1855-1861.
47. Hsieh HG, Loong CC, Lin CY, (2002) Interleukin-17 induces SRC/MAPK cascades activation in human renal epithelial cells. Cytokine 19: 159-174.