A new concept of bioartificial liver based on a fluidized bed bioreactor

Therapeutic Apheresis

Volumn 3, Issue 3, 1999, Pages 264-267

  Doré, Emmanuel ^a   Legallais, Cécile ^a  

^a UNIVERSITÉ DE TECHNOLOGIE DE COMPIÈGNE   (France)

Author keywords

Alginate beads; Fluidization; Hepatocytes; Liver support system

Indexed keywords

ARTICLE; ARTIFICIAL LIVER; BIOREACTOR; FLUIDIZED BED; IMMOBILIZED CELL; LIVER CELL; LIVER FAILURE; LIVER PERFUSION; MASS ACTION; PRIORITY JOURNAL;

BIOREACTORS; HUMANS; LIVER; LIVER, ARTIFICIAL;

EID: 0032801756     PISSN: 10916660     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1526-0968.1999.00152.x     Document Type: Article

References (9)

1. Gislason GT, Lobdell DD, Kelly JH, Sussman NL. A treatment system for implementing an extracorporeal liver assist device. Artif Organs 1994;18(5):385-9.
2. Kamlot A, Rozga J, Watanabe FD, Demetriou AA. Review: Artificial liver support systems. Biotech Bioeng 1996;50: 382-91.
3. Nyberg SL, Shatford RA, Peshwa MV, White JG, Cerra FB, Hu WS. Evaluation of a hepatocyte-entrapment hollow fiber bioreactor: A potentiel bioartificial liver. Biotech Bioeng 1993;41:194-203.
4. Gerlach JC. Development of a hybrid liver support system: A review. Int J Artif Organs 1996;19(11):645-54.
5. Bader A, Knop E, Böker K, Frühauf N, Schüttler W, Oldhafer K, Burkhard R, Pilchmayr R, Sewing KF. A novel bioreactor design for in vitro reconstruction of in vivo liver characteristics. Artif Organs 1995;19(4):368-74.
6. Flendrig LM, Te Velde AA, Chamuleau RAFM. Semipermeable hollow fiber membranes in hepatocyte bioreactors: A prerequisite for a successful bioartificial liver? Artif Organs 1997;21(11):1177-81.
7. Dixit V, Gitnick G. Artificial liver support: State of the art. Scand J Gastroenterol 1996;31(Suppl. 220):101-14.
8. Fremond B, Malandain C, Guyomard C, Chesne C, Guillouzo A, Campion JP. Correction of bilirubin conjugation in the gunn rat using hepatocytes immobilized in alginate gel bead as an extracorporeal bioartificial liver. Cell Transplant 1993; 2:453-60.
9. Kunii D, Levenspiel O, eds. Fluidization Engineering, 2nd Edition. Boston: Butterworth-Heinemann, 1991.