Heterologous expression of a Photorhabdus luminescens syrbactin-like gene cluster results in production of the potent proteasome inhibitor glidobactin A

Microbiological Research

Volumn 168, Issue 2, 2013, Pages 73-76

  Dudnik, Alexey ^a   Bigler, Laurent ^a   Dudler, Robert ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Non ribosomal peptide synthetase; Photorhabdus luminescens; Polyketide synthase; Proteasome inhibitor; Syrbactin

Indexed keywords

NONRIBOSOMAL PEPTIDE SYNTHETASES; PHOTORHABDUS LUMINESCENS; POLYKETIDE SYNTHASES; PROTEASOME INHIBITORS; SYRBACTIN;

GENETIC ENGINEERING; MASS SPECTROMETRY; PEPTIDES;

GENE EXPRESSION;

CYCLOPEPTIDE; GLIDOBACTIN A; NONRIBOSOMAL PEPTIDE SYNTHETASE; PEPTIDE SYNTHASE; PROTEASOME; PROTEASOME INHIBITOR;

BACTERIUM; CATALYSIS; ENZYME ACTIVITY; INHIBITOR; MASS SPECTROMETRY; PEPTIDE;

ARTICLE; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR CLONING; MULTIGENE FAMILY; PHOTORHABDUS; PHYSIOLOGY; PSEUDOMONAS PUTIDA;

CLONING, MOLECULAR; MULTIGENE FAMILY; PEPTIDE SYNTHASES; PEPTIDES, CYCLIC; PHOTORHABDUS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; PSEUDOMONAS PUTIDA;

BACTERIA (MICROORGANISMS); BURKHOLDERIALES; EUKARYOTA; PHOTORHABDUS LUMINESCENS; PHOTORHABDUS LUMINESCENS SUBSP. LAUMONDII; PSEUDOMONAS PUTIDA; PSEUDOMONAS SYRINGAE; PSEUDOMONAS SYRINGAE PV. SYRINGAE;

EID: 84872606912     PISSN: 09445013     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micres.2012.09.006     Document Type: Article

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