SylC catalyzes ureido-bond formation during biosynthesis of the proteasome inhibitor syringolin A

Journal of the American Chemical Society

Volumn 131, Issue 51, 2009, Pages 18263-18265

  Imker, Heidi J ^a   Walsh, Christopher T ^a   Wuest, William M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOACYL; BOND FORMATION; CHEMICAL EQUATIONS; DIPEPTIDE; IN-VITRO; INTRAMOLECULAR CYCLIZATIONS; NATURAL PRODUCTS; PROTEASOME INHIBITORS; PROTEASOMES; TRIPEPTIDE;

AMINO ACIDS; BIOCHEMISTRY; CARBOXYLATION; CHEMICAL BONDS; ORGANIC ACIDS;

BIOSYNTHESIS;

AMINO ACID; ENZYME; MONOMER; NATURAL PRODUCT; PROTEASOME INHIBITOR; SYLC ENZYME; SYRINGOLIN A; UNCLASSIFIED DRUG;

ADENYLATION; ARTICLE; BIOSYNTHESIS; CARBOXYLATION; CATALYSIS; CHEMICAL BOND; CHEMICAL LABELING; CHEMICAL REACTION; CYCLIZATION; POLYMERIZATION; STOICHIOMETRY;

AMINO ACIDS; CATALYSIS; PEPTIDES, CYCLIC; PROTEASOME ENDOPEPTIDASE COMPLEX; UREA;

EID: 73249136918     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja909170u     Document Type: Article

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