Plk1 phosphorylation of Orc2 and Hbo1 contributes to gemcitabine resistance in pancreatic cancer

Molecular Cancer Therapeutics

Volumn 12, Issue 1, 2013, Pages 58-68

  Song, Bing ^a   Liu, X Shawn ^a   Rice, Steven J ^a   Kuang, Shihuan ^a,d   Elzey, Bennett D ^b,d   Konieczny, Stephen F ^a,d   Ratliff, Timothy L ^b,d   Hazbun, Tony ^c,d   Chiorean, Elena G ^e   Liu, Xiaoqi ^a,c  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c PURDUE UNIVERSITY   (United States)

^d Purdue University   (United States)

^e INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (8 CYCLOPENTYL 7 ETHYL 5,6,7,8 TETRAHYDRO 5 METHYL 6 OXO 2 PTERIDINYLAMINO) 3 METHOXY N (1 METHYL 4 PIPERIDINYL)BENZAMIDE; CELL PROTEIN; GEMCITABINE; HBO1 PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; ORC2 PROTEIN; POLO LIKE KINASE 1; PROTEIN C FOS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER RESISTANCE; CONTROLLED STUDY; DNA REPLICATION; DRUG TARGETING; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIZATION; TUMOR XENOGRAFT; WILD TYPE;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CARCINOMA, PANCREATIC DUCTAL; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DEOXYCYTIDINE; DNA REPLICATION; DRUG RESISTANCE, NEOPLASM; FEMALE; HISTONE ACETYLTRANSFERASES; HUMANS; INHIBITORY CONCENTRATION 50; MICE; MICE, NUDE; ORIGIN RECOGNITION COMPLEX; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FOS; PTERIDINES; TISSUE ARRAY ANALYSIS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84872534685     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-12-0632     Document Type: Article

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