Neural Progenitor Cell Implants Modulate Vascular Endothelial Growth Factor and Brain-Derived Neurotrophic Factor Expression in Rat Axotomized Neurons

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Talaverón, Rocío ^a   Matarredona, Esperanza R ^a   de la Cruz, Rosa R ^a   Pastor, Angel M ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NEUROTROPHIN 3; VASCULOTROPIN;

ABDUCENS NERVE; ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; BRAIN STEM; CELL DAMAGE; CELL POPULATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; IMPLANT; NERVE FIBER TRANSECTION; NEURAL STEM CELL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PURKINJE CELL; RAT;

ANIMALS; AXONS; AXOTOMY; BRAIN-DERIVED NEUROTROPHIC FACTOR; MALE; NERVE GROWTH FACTOR; NERVE GROWTH FACTORS; NEURAL STEM CELLS; NEURONS; RATS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA; RATTUS;

EID: 84872534515     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054519     Document Type: Article

References (47)

1. Titmus MJ, Faber DS, (1990) Axotomy-induced alterations in the electrophysiological characteristics of neurons. Prog Neurobiol 35: 1-51.
2. Pastor AM, Delgado-García JM, Martínez-Guijarro FJ, López-García C, de la Cruz RR, (2000) Response of abducens internuclear neurons to axotomy in the adult cat. J Comp Neurol 427: 370-390.
3. Giehl KM, Tetzlaff W, (1996) BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo. Eur J Neurosci 8: 1167-1175.
4. Kobayashi NR, Fan DP, Giehl KM, Bedard AM, Wiegand SJ, et al. (1997) BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration. J Neurosci 17: 9583-9595.
5. Davis-López de Carrizosa MA, Morado-Díaz CJ, Tena JJ, Benítez-Temiño B, Pecero ML, et al. (2009) Complementary actions of BDNF and neurotrophin-3 on the firing patterns and synaptic composition of motoneurons. J Neurosci 29: 575-587.
6. Davis-López de Carrizosa MA, Morado-Díaz CJ, Morcuende S, de la Cruz RR, Pastor AM, (2010) Nerve growth factor regulates the firing patterns and synaptic composition of motoneurons. J Neurosci 30: 8308-8319.
7. Venero JL, Vizuete ML, Revuelta M, Vargas C, Cano J, et al. (2000) Upregulation of BDNF mRNA and trkB mRNA in the nigrostriatal system and in the lesion site following unilateral transection of the medial forebrain bundle. Exp Neurol 161: 38-48.
8. Lee P, Zhuo H, Helke CJ, (2001) Axotomy alters neurotrophin and neurotrophin receptor mRNAs in the vagus nerve and nodose ganglion of the rat. Brain Res Mol Brain Res 87: 31-41.
9. Morcuende S, Matarredona ER, Benítez-Temiño B, Muñoz-Hernández R, Pastor AM, et al. (2011) Differential regulation of the expression of neurotrophin receptors in rat extraocular motoneurons after lesion. J Comp Neurol 519: 2335-2352.
10. Giehl KM, (2001) Trophic dependencies of rodent corticospinal neurons. Rev Neurosci 12: 79-94.
11. de la Cruz RR, Delgado-García JM, Pastor AM, (2000) Discharge characteristics of axotomized abducens internuclear neurons in the adult cat. J Comp Neurol 427: 391-404.
12. Büttner-Ennever JA (2006) Neuroanatomy of the oculomotor system. In: Elsevier, Amsterdam, editors. Progress in Brain Research, vol 151.
13. Benítez-Temiño B, de la Cruz RR, Pastor AM, (2002) Firing properties of axotomized central nervous system neurons recover after graft innervation. J Comp Neurol 444: 324-344.
14. Benítez-Temiño B, de la Cruz RR, Pastor AM, (2003) Grafting of a new target prevents synapse loss in abducens internuclear neurons induced by axotomy. Neuroscience 118: 611-626.
15. Benítez-Temiño B, Morcuende S, Mentis GZ, de la Cruz RR, Pastor AM, (2004) Expression of Trk receptors in the oculomotor system of the adult cat. J Comp Neurol 473: 538-552.
16. Lu P, Jones LL, Snyder EY, Tuszynski MH, (2003) Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol 181: 115-129.
17. Karimi-Abdolrezaee S, Eftekharpour E, Wang J, Morshead CM, Fehlings MG, (2006) Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury. J Neurosci 26: 3377-3389.
18. Fagerlund M, Estrada CP, Jaff N, Svensson M, Brundin L, (2012) Neural stem/progenitor cells transplanted to the hypoglossal nucleus integrates with the host CNS in adult rats and promotes motor neuron survival. Cell Transplant 21: 739-747.
19. Morado-Díaz CJ, Matarredona ER, Davis-López de Carrizosa MA, de la Cruz RR, Pastor AM (2011) Neural progenitor cell implants in the lesioned medial longitudinal fascicle of adult cats regulate synaptic composition of abducens internuclear neurons. Abstr Soc Neurosci: 438.17.
20. Lladó J, Haenggeli C, Maragakis NJ, Snyder EY, Rothstein JD, (2004) Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors. Mol Cell Neurosci 27: 322-331.
21. Capone C, Frigerio S, Fumagalli S, Gelati M, Principato M-C, et al. (2007) Neurosphere-derived cells exert a neuroprotective action by changing the ischemic microenvironment. PLoS ONE 2(4), e373. doi:10.1371/journal.pone0000373.
22. Imitola J, In Park K, Teng YD, Nisim S, Lachyankar M, et al. (2004) Stem cells: cross-talk and developmental programs. Phil Trans R Soc Lond 359: 823-837.
23. Madhavan L, Ourednik V, Ourednik J, (2008) Neural stem/progenitor cells initiate the formation of cellular networks that provide neuroprotection by growth factor-modulated antioxidant expression. Stem Cells 26: 254-265.
24. Tonchev AB, Yamashima T, Guo J, Chaldakov GN, Takakura N, (2007) Expression of angiogenic and neurotrophic factors in the progenitor cell niche of adult monkey subventricular zone. Neuroscience 144: 1425-1435.
25. Sondell M, Sundler F, Kanje M, (2000) Vascular endothelial growth factor is a neurotrophic factor which stimulates axonal outgrowth through the flk-1 receptor. Eur J Neurosci 12: 4243-4254.
26. Sun Y, Jin K, Xie L, Childs J, Mao XO, et al. (2003) VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia. J Clin Invest 111: 1843-1851.
27. Nicoletti J, Sachin S, McCloskey DP, Goodman JH, Scharfmann HE, et al. (2008) Vascular endothelial growth factor (VEGF) is upregulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus. Neuroscience 151: 232-41.
28. Azzouz M, Ralph GS, Storkebaum E, Walmsley LE, Mitrophanous KA, et al. (2004) VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 429: 413-417.
29. McCloskey DP, Croll SD, Scharfman HE, (2005) Depression of synaptic transmission by vascular endothelial growth factor in adult rat hippocampus and evidence for increased efficacy after chronic seizures. J Neurosci 25: 8889-8897.
30. McCloskey DP, Hintz TM, Scharfman HE, (2008) Modulation of vascular endothelial growth factor (VEGF) expression in motor neurons and its electrophysiological effects. Brain Res Bull 76: 36-44.
31. Torroglosa A, Murillo-Carretero M, Romero-Grimaldi C, Matarredona ER, Campos-Caro A, et al. (2007) Nitric oxide decreases subventricular zone precursor proliferation by inhibition of epidermal growth factor receptor and PI3-K/AKT pathway. Stem Cells 25: 88-97.
32. Paxinos G, Watson C (1997) The Rat Brain in Stereotaxic Coordinates. Academic Press. New York.
33. de la Cruz RR, Pastor AM, Martínez-Guijarro FJ, López-García C, Delgado-García JM, (1998) Localization of parvalbumin, calretinin and calbindin D-28k in identified extraocular motoneurons and internuclear neurons of the cat. J Comp Neurol 390: 377-391.
34. Rieux C, Carney R, Lupi D, Dkhissi-Benyahya O, Jansen K, et al. (2002) Analysis of immunohistochemical label of Fos protein in the suprachiasmatic nucleus: comparison of different methods of quantification. J Biol Rhythms 17: 121-136.
35. Duprey-Díaz MV, Blagburn JM, Blanco RE, (2003) Neurotrophin-3 and TrkC in the frog visual system: changes after axotomy. Brain Res 982: 54-63.
36. Gulino R, Lombardo SA, Casabona A, Leanza G, Perciavelle V, (2004) Levels of brain-derived neurotrophic factor and neurotrophin-4 in lumbar motoneurons after low-thoracic spinal cord hemisection. Brain Res 2004: 174-181.
37. Qin DX, Zou Xl, Luo W, Zhang W, Zhang HT, et al. (2006) Expression of some neurotrophins in the spinal motoneurons after cord hemisection in adult rats. Neurosci Lett 410: 222-227.
38. Li X-L, Zhang W, Zhou X, Wang X-Y, Zhang H-T, et al. (2007) Temporal changes in the expression of some neurotrophins in spinal cord transacted adult rats. Neuropeptides 41: 135-143.
39. Conner JM, Lauterborn JC, Yan Q, Gall CM, Varon S, (1997) Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport. J Neurosci 17: 2295-2313.
40. Dugich-Djordjevic MM, Peterson C, Isono F, Obsawa F, Widmer HR, et al. (1995) Immunohistochemical visualization of brain-derived neurotrophic factor in the rat brain. Eur J Neurosci 7: 1831-1839.
41. Lambrechts D, Carmeliet P, (2006) VEGF at the neurovascular interface: therapeutic implications for motor neuron disease. Biochim Biophys Acta 1762: 1109-1121.
42. Zhang H, Li L, Zou X, Song X, Hu Y, et al. (2007) Immunohistochemical distribution of NGF, BDNF, NT-3 and NT-4 in adult rhesus monkey brains. J Histochem Cytochem 55: 1-19.
43. Zhou XF, Rush RA, (1994) Localization of neurotrophin-3 like immunoreactivity in the rat central nervous system. Brain Res 643: 162-172.
44. Pluchino S, Cusimano M, Bacigaluppi M, Martino G, (2010) Remodelling the injured CNS through the establishment of atypical ectopic perivascular neural stem cell niches. Arch Ital Biol 148: 173-183.
45. Wang Y, Jin K, Mao XO, Xie L, Banwait S, et al. (2007) Vascular endothelial growth factor overexpression delays neurodegeneration and prolongs survival in amyotrophic lateral sclerosis mice. J Neurosci 27: 304-307.
46. Tonra JR, Curtis R, Wong V, Cliffer KD, Park JS, et al. (1998) Axotomy upregulates the anterograde transport and expression of brain-derived neurotrophic factor by sensory neurons. J Neurosci 18: 4374-83.
47. Maurer MH, Tripps WK, Feldmann RE Jr, Kuschinsky W, (2003) Expression of vascular endothelial growth factor and its receptors in rat neural stem cells. Neurosci Lett 344: 165-8.