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Catalysis Science and Technology
Volumn 3, Issue 2, 2013, Pages 462-468
Halide bridged trinuclear rhodium complexes and their inhibiting influence on catalysis
Author keywords

[No Author keywords available]
Indexed keywords

CATALYSIS; CHLORINE COMPOUNDS; ENZYME INHIBITION; RHODIUM; SUBSTRATES;
EID: 84872532350     PISSN: 20444753     EISSN: 20444761     Source Type: Journal    
DOI: 10.1039/c2cy20591b     Document Type: Article
Times cited : (17)
References (26)
  • 3
    • 84890757673 scopus 로고    scopus 로고
    • in, ed. A. Evans, Wiley-VCH, Weinheim, ch. 1, 1-31 and references cited therein
    • Y. Chi, W. Tang and X. Zhang, in Modern Rhodium-Catalyzed Organic Reactions, ed., P. A. Evans, Wiley-VCH, Weinheim, 2005, ch. 1, pp. 1-31 and references cited therein
    • (2005) Modern Rhodium-Catalyzed Organic Reactions
    • Chi, Y.1    Tang, W.2    Zhang, X.3
  • 13
  • 16
    • 80052054192 scopus 로고    scopus 로고
    • [2-(3-Methoxy-phenyl)-cyclohex-1-enylmethyl]-dimethylamine is a member of a class of 1,2-disubstituded cyclohexene derivatives which are important intermediates in the synthesis of pharmaceutically active compounds acting on the central nervous system. The challenge is the establishment of the desired relative and absolute stereochemistry of two new stereogenic centers responsible for the pharmacological effect. [2-(3-Methoxy-phenyl)-cyclohex-1-enylmethyl]- dimethylamine can be transformed by a stereoselective hydrogenation to Tramadol, an important analgesic drug used world-wide Elemental analysis of a saturated NaCl solution in methanol showed that in 1.0 mL MeOH ca. 7 mg of NaCl can be dissolved, which corresponds to 0.12 mmol. 105 mg NaBr (1.0 mmol) and 496 mg NaI (3.3 mmol) can be dissolved in 1.0 mL MeOH
    • C. A. Busacca D. R. Fandrick J. J. Song C. H. Senanayake Adv. Synth. Catal. 2011 353 1825 1864
    • (2011) Adv. Synth. Catal. , vol.353 , pp. 1825-1864
    • Busacca, C.A.1    Fandrick, D.R.2    Song, J.J.3    Senanayake, C.H.4
  • 20
    • 67650293102 scopus 로고    scopus 로고
    • All attempts to isolate [Rh3(t-Bu-BisP*) 3(μ3-Cl)2][BF4] from the reaction of the solvate complex with NaCl failed. However, we succeeded while trying to isolate the product complex [Rh(t-Bu-BisP*)(macH2)][BF 4] from CH2Cl2: the hydrogenation product of mac was added to the solvate MeOH complex. The solvent was removed in vacuo and the remaining solid was redissolved in CH2Cl2 and layered with diethyl ether. After a few days single crystals of [Rh3(t-Bu- BisP*)3(μ3-Cl)2][BF4] suitable for X-ray analysis crystallized
    • A. Preetz W. Baumann C. Fischer H.-J. Drexler T. Schmidt R. Thede D. Heller Organometallics 2009 28 3673 3677
    • (2009) Organometallics , vol.28 , pp. 3673-3677
    • Preetz, A.1    Baumann, W.2    Fischer, C.3    Drexler, H.-J.4    Schmidt, T.5    Thede, R.6    Heller, D.7
  • 21
    • 84863304115 scopus 로고    scopus 로고
    • The molecular structure of the trinuclear complex obtained in a different way is shown in Fig. S8, ESI The μ3-bridges of the trinuclear complex are disordered (population: 0.6 Cl, 0.4 Br). The only Cl source can be the solvent CH2Cl2 from which the complex was recrystallized. Only one of the four possible populations is shown
    • C. Kohrt S. Hansen H.-J. Drexler U. Rosenthal A. Schulz D. Heller Inorg. Chem. 2012 51 7377 7383
    • (2012) Inorg. Chem. , vol.51 , pp. 7377-7383
    • Kohrt, C.1    Hansen, S.2    Drexler, H.-J.3    Rosenthal, U.4    Schulz, A.5    Heller, D.6
  • 22
    • 33845281011 scopus 로고
    • The asymmetric hydrogenation of dimethyl itaconate as well as the structure and stability of the catalyst-substrate complex with the DIPAMP system are described in
    • C. R. Landis J. Halpern J. Am. Chem. Soc. 1987 109 1746 1754
    • (1987) J. Am. Chem. Soc. , vol.109 , pp. 1746-1754
    • Landis, C.R.1    Halpern, J.2
  • 25
    • 0029325740 scopus 로고
    • The prochiral olefin (Z)-3-[1-(dimethylamino)-2-methylpent-2-en-3-yl] phenol is also an important precursor of the new analgesic drug Tapentadol which is as an open-chain analogue of Tramadol. The chirality of the new stereogenic centers is very important for the pharmacological effect. The (R,R) stereoisomer of Tapentadol is a novel, centrally acting analgesic with a dual mode of action: μ-opioid receptor (MOR) agonism and norepinephrine reuptake inhibition. Tapentadol is the first oral centrally acting analgesic to be approved in 2008 in the United States for more than a decade. The corresponding (S,S) enantiomer is a very strong opioid. The (R,S) or (S,R) stereoisomers have no analgesic effect
    • K. G. Moloy J. L. Petersen Organometallics 1995 14 2931 2936
    • (1995) Organometallics , vol.14 , pp. 2931-2936
    • Moloy, K.G.1    Petersen, J.L.2

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.