Diastereoselective one-pot knoevenagel condensation/corey-chaykovsky cyclopropanation

Journal of Organic Chemistry

Volumn 78, Issue 2, 2013, Pages 780-785

  Clemens, Jeremy J ^a   Asgian, Juliana L ^a   Busch, Brett B ^a   Coon, Timothy ^a   Ernst, Justin ^a   Kaljevic, Leonard ^a   Krenitsky, Paul J ^a   Neubert, Timothy D ^a   Schweiger, Edwin J ^a,b   Termin, Andreas ^a   Stamos, Dean ^a  

^a VERTEX PHARMACEUTICALS   (United States)

^b DART NEUROSCIENCE LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONCISE SYNTHESIS; CYCLOPROPANATION; CYCLOPROPANE RING; DIASTEREOSELECTIVE; KNOEVENAGEL CONDENSATION; METHOD DEVELOPMENT; ONE POT; ONE-POT METHOD; RACEMIC MIXTURES;

ACETONITRILE; PROPANE;

ALDEHYDES;

ACETONITRILE; ALDEHYDE; BICIFADINE; CYCLOPROPANE;

ARTICLE; COREY CHAYKOVSKY CYCLOPROPANATION; CYCLOPROPANATION; DIASTEREOISOMER; DRUG SYNTHESIS; ENANTIOMER; KNOEVENAGEL CONDENSATION; ONE POT SYNTHESIS; RACEMIC MIXTURE; REACTION ANALYSIS; REACTION OPTIMIZATION; REDUCTION; STEREOCHEMISTRY; STOICHIOMETRY;

ALDEHYDES; CYCLOPROPANES; MOLECULAR STRUCTURE; NITRILES; STEREOISOMERISM;

EID: 84872521413     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo302443k     Document Type: Article

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