Generation and reactions of ammonium ylides in basic two-phase systems: Convenient synthesis of cyclopropanes, oxiranes and alkenes substituted with electron-withdrawing groups

Synlett

Volumn , Issue 7, 1999, Pages 1085-1087

  Jończyk, Andrzej ^a   Konarska, Anna ^a  

^a WARSAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Alkenes; Ammonium ylides; Cyclopropanes; Oxiranes; Quaternary ammonium salts

Indexed keywords

ALDEHYDE; ALKENE; ALKYLATING AGENT; CARBONIC ACID DERIVATIVE; CYCLOPROPANE; DICHLOROMETHANE; ETHYLENE OXIDE; QUATERNARY AMMONIUM DERIVATIVE; SODIUM HYDROXIDE;

ALKYLATION; AQUEOUS SOLUTION; ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; CYCLIZATION; PHYSICAL PHASE; PROTON TRANSPORT; REACTION ANALYSIS; SYNTHESIS;

EID: 0242435030     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1999-2757     Document Type: Article

References (32)

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32. 2 (20 mL) was vigorously stirred, bromide 4d (0.86 g, 5 mmol) then 50% aq NaOH (7 mL) were added (exothermal effect), reaction was continued for 4h, and worked up as described for 5ac. The product was purified by Kugelrohr distillation [bp 125-130 °C (oven)/0.03 Torr] to give 0.81 g (89%) of oily 7cd (Table 3, Entry 6).