The change of cellular membranes on apoptosis: Fluorescence detection

Experimental Oncology

Volumn 34, Issue 3, 2012, Pages 263-268

  Demchenko, A P ^a  

^a PALLADIN INSTITUTE OF BIOCHEMISTRY   (Ukraine)

Author keywords

3 Hydroxyflavones; Apoptosis; F2N12S; Flow cytometry; Fluorescence microscopy; Membrane asymmetry; Phosphatidylserine; Programmed cell death

Indexed keywords

AMINOPHOSPHOLIPID; FLUORESCENT DYE; GLYCOPROTEIN; LIPOCORTIN 5;

APOPTOSIS; BINDING ASSAY; CELL MEMBRANE; CELL STRUCTURE; CELL SURFACE; FLUORESCENCE; REVIEW; SPECTRAL SENSITIVITY;

ANNEXIN A5; APOPTOSIS; CELL MEMBRANE; FLAVONOIDS; FLOW CYTOMETRY; FLUORESCENT DYES; HUMANS; PHOSPHATIDYLSERINES; PHOSPHOLIPIDS; SURFACE PROPERTIES;

EID: 84872482577     PISSN: 18129269     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (49)

1. Coppola JM, Ross BD, Rehemtulla A. Noninvasive imaging of apoptosis and its application in cancer therapeutics. Clin Cancer Res 2008; 14: 2492-501.
2. Kim R, Tanabe K, Uchida Y, et al. Current status of the molecular mechanisms of anticancer drug-induced apoptosis. The contribution of molecular-level analysis to cancer chemotherapy. Cancer Chemother Pharmacol 2002; 50: 343-52.
3. Ulukaya E, Acilan C, Yilmaz Y. Apoptosis: Why and how does it occur in biology? Cell Biochem Funct 2011; 29: 468-80.
4. Pereira WO, Amarante-Mendes GP. Apoptosis: A programme of cell death or cell disposal? Scand J Immunol 2011; 73: 401-7.
5. Boersma HH, Kietselaer BL, Stolk LM, et al. Past, present, and future of annexin a5: From protein discovery to clinical applications. J Nucl Med 2005; 46: 2035-50.
6. Balasubramanian K, Schroit AJ. Aminophospholipid asymmetry: A matter of life and death. Annu Rev Physiol 2003; 65: 701-34.
7. Ravichandran KS. Find-me and eat-me signals in apoptotic cell clearance: Progress and conundrums. J Exp Med 2010; 207: 1807-17.
8. Kiessling V, Wan C, Tamm LK. Domain coupling in asymmetric lipid bilayers. Biochim Biophys Acta 2009; 1788: 64-71.
9. Yamaji-Hasegawa A, Tsujimoto M. Asymmetric distribution of phospholipids in biomembranes. Biol Pharm Bull 2006; 29: 1547-53.
10. van Meer G. Cellular lipidomics. EMBO J 2005; 24: 3159-65.
11. Zwaal RF, Comfurius P, Bevers EM. Surface exposure of phosphatidylserine in pathological cells. Cell Mol Life Sci 2005; 62: 971-88.
12. Oncul S, Klymchenko AS, Kucherak OA, et al. Liquid ordered phase in cell membranes evidenced by a hydration-sensitive probe: Effects of cholesterol depletion and apoptosis. Biochim Biophys Acta 2010; 1798: 1436-43.
13. Schutters K, Reutelingsperger C. Phosphatidylserine targeting for diagnosis and treatment of human diseases. Apoptosis 2010; 15: 1072-82.
14. Korngold EC, Jaffer FA, Weissleder R, et al. Noninvasive imaging of apoptosis in cardiovascular disease. Heart Fail Rev 2008; 13: 163-73.
15. Ran S, Thorpe PE. Phosphatidylserine is a marker of tumor vasculature and a potential target for cancer imaging and therapy. Int J Radiat Oncol Biol Phys 2002; 54: 1479-84.
16. Ran S, Downes A, Thorpe PE. Increased exposure of anionic phospholipids on the surface of tumor blood vessels. Cancer Res 2002; 62: 6132-40.
17. Kerbiriou-Nabias D, Geldwerth-Feniger D. Exposition membranaire de la phosphatidylsérine et activité procoagulante des plaquettes. Hematologie 2007; 13: 94-109.
18. Ravichandran KS, Lorenz U. Engulfment of apoptotic cells: Signals for a good meal. Nat Rev Immunol 2007; 7: 964-74.
19. van Engeland M, Nieland LJ, Ramaekers FC, et al. Annexin v-affinity assay: A review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 1998; 31: 1-9.
20. Hanshaw RG, Smith BD. New reagents for phosphatidylserine recognition and detection of apoptosis. Bioorg Med Chem 2005; 13: 5035-42.
21. Ntziachristos V, Schellenberger EA, Ripoll J, et al. Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin v-cy5.5 conjugate. Proc Natl Acad Sci USA 2004; 101: 12294-9.
22. Le Gac S, Vermes I, van den Berg A. Quantum dots based probes conjugated to annexin v for photostable apoptosis detection and imaging. Nano Lett 2006; 6: 1863-9.
23. Mourdjeva M, Kyurkchiev D, Mandinova A, et al. Dynamics of membrane translocation of phosphatidylserine during apoptosis detected by a monoclonal antibody. Apoptosis 2005; 10: 209-17.
24. Balasubramanian K, Bevers EM, Willems GM, et al. Binding of annexin v to membrane products of lipid peroxidation. Biochemistry 2001; 40: 8672-6.
25. Kuijpers TW, Maianski NA, Tool AT, et al. Neutrophils in barth syndrome (bths) avidly bind annexin-v in the absence of apoptosis. Blood 2004; 103: 3915-23.
26. Dong HP, Holth A, Ruud MG, et al. Measurement of apoptosis in cytological specimens by flow cytometry: Comparison of annexin V, caspase cleavage and dutp incorporation assays. Cytopathology 2011; 22: 365-72.
27. Meers P, Mealy T. Calcium-dependent annexin v binding to phospholipids: Stoichiometry, specificity, and the role of negative charge. Biochemistry 1993; 32: 11711-21.
28. Smith C, Mehta R, Gibson DF, et al. Characterization of a recombinant form of annexin VI for detection of apoptosis. Bioconjug Chem 2010; 21: 1554-8.
29. Alam IS, Neves AA, Witney TH, et al. Comparison of the c2a domain of synaptotagmin-i and annexin-v as probes for detecting cell death. Bioconjug Chem 2010; 21: 884-91.
30. Koulov AV, Hanshaw RG, Stucker KA, et al. Biophysical studies of a synthetic mimic of the apoptosis-detecting protein annexin V. Israel J Chem 2005; 45: 373-9.
31. DiVittorio KM, Johnson JR, Johansson E, et al. Synthetic peptides with selective affinity for apoptotic cells. Org Biomol Chem 2006; 4: 1966-76.
32. Smith B, Xiao S, Wolter W, et al. In vivo targeting of cell death using a synthetic fluorescent molecular probe. Apoptosis 2011; 16: 722-31.
33. Quinti L, Weissleder R, Tung CH. A fluorescent nanosensor for apoptotic cells. Nano Lett 2006; 6: 488-90.
34. Thapa N, Kim S, So IS, et al. Discovery of a phosphatidylserine- recognizing peptide and its utility in molecular imaging of tumour apoptosis. J Cell Mol Med 2008; 12: 1649-60.
35. Xiong C, Brewer K, Song S, et al. Peptide-based imaging agents targeting phosphatidylserine for the detection of apoptosis. J Med Chem 2011; 54: 1825-35.
36. Zheng H, Wang F, Wang Q, et al. Cofactor-free detection of phosphatidylserine with cyclic peptides mimicking lactadherin. J Am Chem Soc 2011; 133: 15280-3.
37. Kim YE, Chen J, Chan JR, et al. Engineering a polarity-sensitive biosensor for time-lapse imaging of apoptotic processes and degeneration. Nat Methods 2010; 7: 67-73.
38. Bilyy R, Stoika R. Search for novel cell surface markers of apoptotic cells. Autoimmunity 2007; 40: 249-53.
39. Bilyy R, Tomyn A, Kit Y, et al. Detection of dying cells using lectin-conjugated fluorescent and luminescent nanoparticles. Materialwissenschaft Werkstofftechnik 2009; 40: 234-7.
40. Laakko T, King L, Fraker P. Versatility of merocyanine 540 for the flow cytometric detection of apoptosis in human and murine cells. J Immunol Methods 2002; 261: 129-39.
41. Bose S, Tuunainen I, Parry M, et al. Binding of cationic liposomes to apoptotic cells. Anal Biochem 2004; 331: 385-94.
42. Zhu C, Yang Q, Liu L, et al. A potent fluorescent probe for the detection of cell apoptosis. Chem Commun (Camb) 2011; 47: 5524-6.
43. Demchenko AP, Mely Y, Duportail G, et al. Monitoring biophysical properties of lipid membranes by environment-sensitive fluorescent probes. Biophys J 2009; 96: 3461-70.
44. Demchenko AP, Yesylevskyy SO. Nanoscopic description of biomembrane electrostatics: Results of molecular dynamics simulations and fluorescence probing. Chem Phys Lipids 2009; 160: 63-84.
45. Schlegel RA, Stevens M, Lumley-Sapanski K, et al. Altered lipid packing identifies apoptotic thymocytes. Immunol Lett 1993; 36: 283-8.
46. Matsura T, Togawa A, Kai M, et al. The presence of oxidized phosphatidylserine on Fas-mediated apoptotic cell surface. Biochim Biophys Acta 2005; 1736: 181-8.
47. Demchenko AP. The concept of lambda-ratiometry in fluorescence sensing and imaging. J Fluoresc 2010; 20: 1099-128.
48. Shynkar VV, Klymchenko AS, Kunzelmann C, et al. Fluorescent biomembrane probe for ratiometric detection of apoptosis. J Am Chem Soc 2007; 129: 2187-93.
49. Demchenko AP. Introduction to fluorescence sensing. Amsterdam: Springer; 2009.