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Volumn 22, Issue 6, 2011, Pages 365-372

Measurement of apoptosis in cytological specimens by flow cytometry: Comparison of Annexin V, caspase cleavage and dUTP incorporation assays

Author keywords

Annexin V; Apoptosis; Caspase; DUTP incorporation; Fine needle aspiration cytology; Flow cytometry; Metastatic carcinoma; Reactive mesothelial cells; Serous effusions

Indexed keywords

CASPASE 3; CASPASE 8; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; LIPOCORTIN 5;

EID: 81355147113     PISSN: 09565507     EISSN: 13652303     Source Type: Journal    
DOI: 10.1111/j.1365-2303.2010.00811.x     Document Type: Article
Times cited : (7)

References (47)
  • 2
    • 28244442462 scopus 로고    scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease
    • Fadeel B, Orrenius S. Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease. J Intern Med 2005;258:479-517.
    • (2005) J Intern Med , vol.258 , pp. 479-517
    • Fadeel, B.1    Orrenius, S.2
  • 3
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995;267:1456-62.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 4
    • 24044438464 scopus 로고    scopus 로고
    • Apoptotic pathways and therapy resistance in human malignancies
    • Viktorsson K, Lewensohn R, Zhivotovsky B. Apoptotic pathways and therapy resistance in human malignancies. Adv Cancer Res 2005;94:143-96.
    • (2005) Adv Cancer Res , vol.94 , pp. 143-196
    • Viktorsson, K.1    Lewensohn, R.2    Zhivotovsky, B.3
  • 6
    • 35748978560 scopus 로고    scopus 로고
    • Flow cytometric immunphenotyping of epithelial cancer cells in effusions-Technical considerations and pitfalls
    • Dong HP, Holth A, Berner A, Davidson B, Risberg B. Flow cytometric immunphenotyping of epithelial cancer cells in effusions-Technical considerations and pitfalls. Cytometry B Clin Cytom 2007;72B:332-43.
    • (2007) Cytometry B Clin Cytom , vol.72 , pp. 332-343
    • Dong, H.P.1    Holth, A.2    Berner, A.3    Davidson, B.4    Risberg, B.5
  • 7
    • 0028942106 scopus 로고
    • Human neutrophils lose their surface Fc gamma RIII and acquire Annexin-V binding sites during apoptosis in vitro
    • Homburg CH, de Haas M, von dem Borne AE et al. Human neutrophils lose their surface Fc gamma RIII and acquire Annexin-V binding sites during apoptosis in vitro. Blood 1995;85:532-40.
    • (1995) Blood , vol.85 , pp. 532-540
    • Homburg, C.H.1    de Haas, M.2    von dem Borne, A.E.3
  • 8
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin-V
    • Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin-V. J Immunol Methods 1995;184:39-51.
    • (1995) J Immunol Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 9
    • 0029945204 scopus 로고    scopus 로고
    • A novel assay to measure loss of plasma membrane asymmetry during apoptosis of adherent cells in culture
    • van Engeland M, Ramaekers FC, Schutte B, Reutelingsperger CP. A novel assay to measure loss of plasma membrane asymmetry during apoptosis of adherent cells in culture. Cytometry 1996;24:131-9.
    • (1996) Cytometry , vol.24 , pp. 131-139
    • van Engeland, M.1    Ramaekers, F.C.2    Schutte, B.3    Reutelingsperger, C.P.4
  • 10
    • 0031985647 scopus 로고    scopus 로고
    • Annexin-V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure
    • van Engeland M, Nieland LJ, Ramaekers FC, Schutte B, Reutelingsperger CP. Annexin-V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 1998;31:1-9.
    • (1998) Cytometry , vol.31 , pp. 1-9
    • van Engeland, M.1    Nieland, L.J.2    Ramaekers, F.C.3    Schutte, B.4    Reutelingsperger, C.P.5
  • 11
    • 39149116749 scopus 로고    scopus 로고
    • Multiparametric analysis of cells with different mitochondrial membrane potential during apoptosis by polychromatic flow cytometry
    • Troiano L, Ferraresi R, Lugli E et al. Multiparametric analysis of cells with different mitochondrial membrane potential during apoptosis by polychromatic flow cytometry. Nat Protoc 2007;2:2719-27.
    • (2007) Nat Protoc , vol.2 , pp. 2719-2727
    • Troiano, L.1    Ferraresi, R.2    Lugli, E.3
  • 12
    • 0028864003 scopus 로고
    • Discrimination of apoptotic thymocytes by forward light scatter
    • Ormerod MG, Paul F, Cheetham M, Sun XM. Discrimination of apoptotic thymocytes by forward light scatter. Cytometry 1995;21:300-4.
    • (1995) Cytometry , vol.21 , pp. 300-304
    • Ormerod, M.G.1    Paul, F.2    Cheetham, M.3    Sun, X.M.4
  • 13
    • 34249999528 scopus 로고    scopus 로고
    • Live-cell assay for detection of apoptosis by dual-laser flow cytometry using Hoechst 33342 and 7-amino-actinomycin D
    • Schmid I, Uittenbogaart C, Jamieson BD. Live-cell assay for detection of apoptosis by dual-laser flow cytometry using Hoechst 33342 and 7-amino-actinomycin D. Nat Protoc 2007;2:187-90.
    • (2007) Nat Protoc , vol.2 , pp. 187-190
    • Schmid, I.1    Uittenbogaart, C.2    Jamieson, B.D.3
  • 14
    • 0034213041 scopus 로고    scopus 로고
    • Flow cytometry detection of caspase 3 activation in preapoptotic leukemic cells
    • Belloc F, Belaud-Rotureau MA, Lavignolle V et al. Flow cytometry detection of caspase 3 activation in preapoptotic leukemic cells. Cytometry 2000;40:151-60.
    • (2000) Cytometry , vol.40 , pp. 151-160
    • Belloc, F.1    Belaud-Rotureau, M.A.2    Lavignolle, V.3
  • 15
    • 0027269557 scopus 로고
    • Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
    • Gorczyca W, Gong J, Darzynkiewicz Z. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res 1993;53:1945-51.
    • (1993) Cancer Res , vol.53 , pp. 1945-1951
    • Gorczyca, W.1    Gong, J.2    Darzynkiewicz, Z.3
  • 16
    • 44949109325 scopus 로고    scopus 로고
    • Methods for simultaneous measurement of apoptosis and cell surface phenotype of epithelial cells in effusions by flow cytometry
    • Dong HP, Kleinberg L, Davidson B, Risberg B. Methods for simultaneous measurement of apoptosis and cell surface phenotype of epithelial cells in effusions by flow cytometry. Nat Protoc 2008;3:955-64.
    • (2008) Nat Protoc , vol.3 , pp. 955-964
    • Dong, H.P.1    Kleinberg, L.2    Davidson, B.3    Risberg, B.4
  • 17
    • 67349160447 scopus 로고    scopus 로고
    • Cleaved caspases and NF-κB p65 are prognostic factors in metastatic ovarian carcinoma
    • Kleinberg L, Dong HP, Holth A et al. Cleaved caspases and NF-κB p65 are prognostic factors in metastatic ovarian carcinoma. Hum Pathol 2009;40:795-806.
    • (2009) Hum Pathol , vol.40 , pp. 795-806
    • Kleinberg, L.1    Dong, H.P.2    Holth, A.3
  • 18
    • 70449715615 scopus 로고    scopus 로고
    • Evaluation of cell surface expression of phosphatidylserine in ovarian carcinoma effusions using the Annexin-V/7-AAD assay - Clinical relevance and comparison to other apoptosis parameters
    • Dong HP, Holth A, Kleinberg L et al. Evaluation of cell surface expression of phosphatidylserine in ovarian carcinoma effusions using the Annexin-V/7-AAD assay - Clinical relevance and comparison to other apoptosis parameters. Am J Clin Pathol 2009;132:756-62.
    • (2009) Am J Clin Pathol , vol.132 , pp. 756-762
    • Dong, H.P.1    Holth, A.2    Kleinberg, L.3
  • 20
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 21
    • 0027205172 scopus 로고
    • Induction of DNA strand breaks associated with apoptosis during treatment of leukemias
    • Gorczyca W, Bigman K, Mittelman A et al. Induction of DNA strand breaks associated with apoptosis during treatment of leukemias. Leukemia 1993;7:659-70.
    • (1993) Leukemia , vol.7 , pp. 659-670
    • Gorczyca, W.1    Bigman, K.2    Mittelman, A.3
  • 24
    • 0036547417 scopus 로고    scopus 로고
    • Death and anti-death: tumour resistance to apoptosis
    • Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2002;2:277-88.
    • (2002) Nat Rev Cancer , vol.2 , pp. 277-288
    • Igney, F.H.1    Krammer, P.H.2
  • 25
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl
    • Martin SJ, Reutelingsperger CP, McGahon AJ et al. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J Exp Med 1995;182:1545-56.
    • (1995) J Exp Med , vol.182 , pp. 1545-1556
    • Martin, S.J.1    Reutelingsperger, C.P.2    McGahon, A.J.3
  • 26
    • 0025250043 scopus 로고
    • Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers
    • Andree HA, Reutelingsperger CP, Hauptmann R et al. Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers. J Biol Chem 1990;265:4923-8.
    • (1990) J Biol Chem , vol.265 , pp. 4923-4928
    • Andree, H.A.1    Reutelingsperger, C.P.2    Hauptmann, R.3
  • 27
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman G, Reutingsperger CP, Kuijten GA et al. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 1994;84:1415-20.
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutingsperger, C.P.2    Kuijten, G.A.3
  • 29
    • 0034760195 scopus 로고    scopus 로고
    • The role of Desmin and N-cadherin in effusion cytology: a comparative study using established markers of mesothelial and epithelial cells
    • Davidson B, Nielsen S, Christensen J et al. The role of Desmin and N-cadherin in effusion cytology: a comparative study using established markers of mesothelial and epithelial cells. Am J Surg Pathol 2001;25:1405-12.
    • (2001) Am J Surg Pathol , vol.25 , pp. 1405-1412
    • Davidson, B.1    Nielsen, S.2    Christensen, J.3
  • 30
    • 0032078365 scopus 로고    scopus 로고
    • Flow cytometric assessment of three different methods for the measurement of in vitro apoptosis
    • Pepper C, Thomas A, Tucker H, Hoy T, Bentley P. Flow cytometric assessment of three different methods for the measurement of in vitro apoptosis. Leuk Res 1998;22:439-44.
    • (1998) Leuk Res , vol.22 , pp. 439-444
    • Pepper, C.1    Thomas, A.2    Tucker, H.3    Hoy, T.4    Bentley, P.5
  • 31
    • 0033603823 scopus 로고    scopus 로고
    • Annexin-V staining due to loss of membrane asymmetry can be reversible and precede commitment to apoptotic death
    • Hammill AK, Uhr JW, Scheuermann RH. Annexin-V staining due to loss of membrane asymmetry can be reversible and precede commitment to apoptotic death. Exp Cell Res 1999;251:16-21.
    • (1999) Exp Cell Res , vol.251 , pp. 16-21
    • Hammill, A.K.1    Uhr, J.W.2    Scheuermann, R.H.3
  • 32
    • 0036486828 scopus 로고    scopus 로고
    • Reversible phosphatidylserine expression on blood granulocytes related to membrane perturbation but not DNA strand breaks
    • Yang MY, Chuang H, Chen RF, Yang KD. Reversible phosphatidylserine expression on blood granulocytes related to membrane perturbation but not DNA strand breaks. J Leukoc Biol 2002;71:231-7.
    • (2002) J Leukoc Biol , vol.71 , pp. 231-237
    • Yang, M.Y.1    Chuang, H.2    Chen, R.F.3    Yang, K.D.4
  • 33
    • 65249141172 scopus 로고    scopus 로고
    • Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane
    • Stowell SR, Karmakar S, Arthur CM et al. Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane. Mol Biol Cell 2009;20:1408-18.
    • (2009) Mol Biol Cell , vol.20 , pp. 1408-1418
    • Stowell, S.R.1    Karmakar, S.2    Arthur, C.M.3
  • 35
    • 23144448574 scopus 로고    scopus 로고
    • Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes
    • Elliott JI, Surprenant A, Marelli-Berg FM et al. Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes. Nat Cell Biol 2005;7:808-16.
    • (2005) Nat Cell Biol , vol.7 , pp. 808-816
    • Elliott, J.I.1    Surprenant, A.2    Marelli-Berg, F.M.3
  • 36
    • 0142103332 scopus 로고    scopus 로고
    • Dimeric galectin-1 induces surface exposure of phosphatidylserine and phagocytic recognition of leukocytes without inducing apoptosis
    • Dias-Baruffi M, Zhu H, Cho M et al. Dimeric galectin-1 induces surface exposure of phosphatidylserine and phagocytic recognition of leukocytes without inducing apoptosis. J Biol Chem 2003;278:41282-93.
    • (2003) J Biol Chem , vol.278 , pp. 41282-41293
    • Dias-Baruffi, M.1    Zhu, H.2    Cho, M.3
  • 37
    • 34547138164 scopus 로고    scopus 로고
    • Regulated externalization of phosphatidylserine at the cell surface: implications for apoptosis
    • Balasubramanian K, Mirnikjoo B, Schroit AJ. Regulated externalization of phosphatidylserine at the cell surface: implications for apoptosis. J Biol Chem 2007;282:18357-64.
    • (2007) J Biol Chem , vol.282 , pp. 18357-18364
    • Balasubramanian, K.1    Mirnikjoo, B.2    Schroit, A.J.3
  • 38
    • 0025743796 scopus 로고
    • Elevated expression of phosphatidylserine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes
    • Utsugi T, Schroit AJ, Connor J, Bucana CD, Fidler IJ. Elevated expression of phosphatidylserine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes. Cancer Res 1991;51:3062-6.
    • (1991) Cancer Res , vol.51 , pp. 3062-3066
    • Utsugi, T.1    Schroit, A.J.2    Connor, J.3    Bucana, C.D.4    Fidler, I.J.5
  • 39
    • 0345112372 scopus 로고
    • Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation
    • Connor J, Bucana C, Fidler IJ, Schroit AJ. Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation. Proc Natl Acad Sci U S A 1989;86:3184-8.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 3184-3188
    • Connor, J.1    Bucana, C.2    Fidler, I.J.3    Schroit, A.J.4
  • 40
    • 0028200038 scopus 로고
    • Annexin-V as a probe of the contribution of anionic phospholipids to the procoagulant activity of tumour cell surfaces
    • Sugimura M, Donato R, Kakkar VV, Scully MF. Annexin-V as a probe of the contribution of anionic phospholipids to the procoagulant activity of tumour cell surfaces. Blood Coagul Fibrinolysis 1994;5:365-73.
    • (1994) Blood Coagul Fibrinolysis , vol.5 , pp. 365-373
    • Sugimura, M.1    Donato, R.2    Kakkar, V.V.3    Scully, M.F.4
  • 41
    • 0026453558 scopus 로고
    • Binding of Annexin-V to a human ovarian carcinoma cell line (OC-2008). Contrasting effects on cell surface factor VIIa/tissue factor activity and prothrombinase activity
    • Rao LV, Tait JF, Hoang AD. Binding of Annexin-V to a human ovarian carcinoma cell line (OC-2008). Contrasting effects on cell surface factor VIIa/tissue factor activity and prothrombinase activity. Thromb Res 1992;67:517-31.
    • (1992) Thromb Res , vol.67 , pp. 517-531
    • Rao, L.V.1    Tait, J.F.2    Hoang, A.D.3
  • 42
    • 0346256782 scopus 로고    scopus 로고
    • Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2)
    • Woehlecke H, Pohl A, Alder-Baerens N, Lage H, Herrmann A. Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2). Biochem J 2003;376:489-95.
    • (2003) Biochem J , vol.376 , pp. 489-495
    • Woehlecke, H.1    Pohl, A.2    Alder-Baerens, N.3    Lage, H.4    Herrmann, A.5
  • 43
    • 18544381354 scopus 로고    scopus 로고
    • Surface exposure of phosphatidylserine in pathological cells
    • Zwaal RF, Comfurius P, Bevers EM. Surface exposure of phosphatidylserine in pathological cells. Cell Mol Life Sci 2005;62:971-88.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 971-988
    • Zwaal, R.F.1    Comfurius, P.2    Bevers, E.M.3
  • 44
    • 47749155653 scopus 로고    scopus 로고
    • Cancer related inflammation: the macrophage connection
    • Sica A, Allavena P, Mantovani A. Cancer related inflammation: the macrophage connection. Cancer Lett 2008;267:204-15.
    • (2008) Cancer Lett , vol.267 , pp. 204-215
    • Sica, A.1    Allavena, P.2    Mantovani, A.3
  • 45
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010;140:935-50.
    • (2010) Cell , vol.140 , pp. 935-950
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 46
    • 33644652161 scopus 로고    scopus 로고
    • NK- and B-cell infiltration correlates with worse outcome in metastatic ovarian carcinoma
    • Dong HP, Elstrand MB, Holth A et al. NK- and B-cell infiltration correlates with worse outcome in metastatic ovarian carcinoma. Am J Clin Pathol 2006;125:451-8.
    • (2006) Am J Clin Pathol , vol.125 , pp. 451-458
    • Dong, H.P.1    Elstrand, M.B.2    Holth, A.3
  • 47
    • 43949098268 scopus 로고    scopus 로고
    • New insights into the biology of peritoneal mesothelial cells: the roles of epithelial-to-mesenchymal transition and cellular senescence
    • Witowski J, Ksiazek K, Jorres A. New insights into the biology of peritoneal mesothelial cells: the roles of epithelial-to-mesenchymal transition and cellular senescence. Nephron Exp Nephrol 2008;108:e69-73.
    • (2008) Nephron Exp Nephrol , vol.108
    • Witowski, J.1    Ksiazek, K.2    Jorres, A.3


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