Monocyte chemoattractant protein-1 affects migration of hippocampal neural progenitors following status epilepticus in rats

Journal of Neuroinflammation

Volumn 10, Issue , 2013, Pages

  Hung, Yu Wen ^a,b   Lai, Ming Tsong ^a,b   Tseng, Yi Jhan ^a,b   Chou, Chien Chen ^a,b   Lin, Yung Yang ^a,b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Chemokine (C C motif) receptor 2 (CCR2); Dentate gyrus; Epileptogenesis; Monocyte chemoattractant protein 1 (MCP 1); Neuroinflammation; Neuronal progenitor migration; Pilocarpine induced status epilepticus; Rats

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR2 ANTAGONIST; DOUBLECORTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PILOCARPINE; PROTEIN; PROX1 PROTEIN; RS 102895; UNCLASSIFIED DRUG; CCL2 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DENTATE GYRUS; ENZYME LINKED IMMUNOSORBENT ASSAY; EPILEPSY; EPILEPTIC STATE; EPILEPTOGENESIS; GENE CONTROL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; NEURAL STEM CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL MOTION; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CELL MOVEMENT; CHEMOKINE CCL2; HIPPOCAMPUS; MALE; NEURAL STEM CELLS; RATS; RATS, SPRAGUE-DAWLEY; STATUS EPILEPTICUS;

EID: 84872463045     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-10-11     Document Type: Article

References (46)

1. Spencer SS. When should temporal-lobe epilepsy be treated surgically?. Lancet Neurol 2002, 1:375-382. 10.1016/S1474-4422(02)00163-1, 12849399.
2. Buckmaster PS. Laboratory animal models of temporal lobe epilepsy. Comp Med 2004, 54:473-485.
3. Dalby NO, Mody I. The process of epileptogenesis: a pathophysiological approach. Curr Opin Neurol 2001, 14:187-192. 10.1097/00019052-200104000-00009, 11262734.
4. Parent JM, Yu TW, Leibowitz RT, Geschwind DH, Sloviter RS, Lowenstein DH. Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J Neurosci 1997, 17:3727-3738.
5. Vezzani A, Granata T. Brain inflammation in epilepsy: experimental and clinical evidence. Epilepsia 2005, 46:1724-1743. 10.1111/j.1528-1167.2005.00298.x, 16302852.
6. Chang BS, Lowenstein DH. Epilepsy. N Engl J Med 2003, 349:1257-1266. 10.1056/NEJMra022308, 14507951.
7. Turrin NP, Rivest S. Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy. Neurobiol Dis 2004, 16:321-334. 10.1016/j.nbd.2004.03.010, 15193289.
8. Vezzani A, French J, Bartfai T, Baram TZ. The role of inflammation in epilepsy. Nat Rev Neurol 2011, 7:31-40. 10.1038/nrneurol.2010.178, 3378051, 21135885.
9. Vezzani A, Balosso S, Ravizza T. The role of cytokines in the pathophysiology of epilepsy. Brain Behav Immun 2008, 22:797-803. 10.1016/j.bbi.2008.03.009, 18495419.
10. Asensio VC, Campbell IL. Chemokines in the CNS: plurifunctional mediators in diverse states. Trends Neurosci 1999, 22:504-512. 10.1016/S0166-2236(99)01453-8, 10529818.
11. Cartier L, Hartley O, Dubois-Dauphin M, Krause KH. Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases. Brain Res Brain Res Rev 2005, 48:16-42. 10.1016/j.brainresrev.2004.07.021, 15708626.
12. Huang D, Han Y, Rani MR, Glabinski A, Trebst C, Sorensen T, Tani M, Wang J, Chien P, O'Bryan S, Bielecki B, Zhou ZL, Majumder S, Ransohoff RM. Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation. Immunol Rev 2000, 177:52-67. 10.1034/j.1600-065X.2000.17709.x, 11138785.
13. Miller RJ, Rostene W, Apartis E, Banisadr G, Biber K, Milligan ED, White FA, Zhang J. Chemokine action in the nervous system. J Neurosci 2008, 28:11792-11795. 10.1523/JNEUROSCI.3588-08.2008, 2746239, 19005041.
14. Choi J, Nordli DR, Alden TD, DiPatri A, Laux L, Kelley K, Rosenow J, Schuele SU, Rajaram V, Koh S. Cellular injury and neuroinflammation in children with chronic intractable epilepsy. J Neuroinflammation 2009, 6:38. 10.1186/1742-2094-6-38, 2811703, 20021679.
15. van Gassen KL, de Wit M, Koerkamp MJ, Rensen MG, van Rijen PC, Holstege FC, Lindhout D, de Graan PN. Possible role of the innate immunity in temporal lobe epilepsy. Epilepsia 2008, 49:1055-1065. 10.1111/j.1528-1167.2007.01470.x, 18076643.
16. Wu Y, Wang X, Mo X, Xi Z, Xiao F, Li J, Zhu X, Luan G, Wang Y, Li Y, Zhang J. Expression of monocyte chemoattractant protein-1 in brain tissue of patients with intractable epilepsy. Clin Neuropathol 2008, 27:55-63.
17. Foresti ML, Arisi GM, Katki K, Montanez A, Sanchez RM, Shapiro LA. Chemokine CCL2 and its receptor CCR2 are increased in the hippocampus following pilocarpine-induced status epilepticus. J Neuroinflammation 2009, 6:40. 10.1186/1742-2094-6-40, 2804573, 20034406.
18. Manley NC, Bertrand AA, Kinney KS, Hing TC, Sapolsky RM. Characterization of monocyte chemoattractant protein-1 expression following a kainate model of status epilepticus. Brain Res 2007, 1182:138-143.
19. Stamatovic SM, Shakui P, Keep RF, Moore BB, Kunkel SL, Van Rooijen N, Andjelkovic AV. Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability. J Cereb Blood Flow Metab 2005, 25:593-606. 10.1038/sj.jcbfm.9600055, 15689955.
20. Yadav A, Saini V, Arora S. MCP-1: chemoattractant with a role beyond immunity: a review. Clin Chim Acta 2010, 411:1570-1579. 10.1016/j.cca.2010.07.006, 20633546.
21. Iyer AM, Zurolo E, Boer K, Baayen JC, Giangaspero F, Arcella A, Di Gennaro GC, Esposito V, Spliet WG, van Rijen PC, Troost D, Gorter JA, Aronica E. Tissue plasminogen activator and urokinase plasminogen activator in human epileptogenic pathologies. Neuroscience 2010, 167:929-945. 10.1016/j.neuroscience.2010.02.047, 20219643.
22. Widera D, Holtkamp W, Entschladen F, Niggemann B, Zanker K, Kaltschmidt B, Kaltschmidt C. MCP-1 induces migration of adult neural stem cells. Eur J Cell Biol 2004, 83:381-387. 10.1078/0171-9335-00403, 15506562.
23. Yan YP, Sailor KA, Lang BT, Park SW, Vemuganti R, Dempsey RJ. Monocyte chemoattractant protein-1 plays a critical role in neuroblast migration after focal cerebral ischemia. J Cereb Blood Flow Metab 2007, 27:1213-1224. 10.1038/sj.jcbfm.9600432, 17191078.
24. Belmadani A, Tran PB, Ren D, Miller RJ. Chemokines regulate the migration of neural progenitors to sites of neuroinflammation. J Neurosci 2006, 26:3182-3191. 10.1523/JNEUROSCI.0156-06.2006, 2740990, 16554469.
25. Overstreet-Wadiche LS, Bromberg DA, Bensen AL, Westbrook GL. Seizures accelerate functional integration of adult-generated granule cells. J Neurosci 2006, 26:4095-4103. 10.1523/JNEUROSCI.5508-05.2006, 16611826.
26. Walter C, Murphy BL, Pun RY, Spieles-Engemann AL, Danzer SC. Pilocarpine-induced seizures cause selective time-dependent changes to adult-generated hippocampal dentate granule cells. J Neurosci 2007, 27:7541-7552. 10.1523/JNEUROSCI.0431-07.2007, 17626215.
27. Parent JM. Adult neurogenesis in the intact and epileptic dentate gyrus. Prog Brain Res 2007, 163:529-540.
28. Zheng Y, Moussally J, Cash SS, Karnam HB, Cole AJ. Intravenous levetiracetam in the rat pilocarpine-induced status epilepticus model: behavioral, physiological and histological studies. Neuropharmacology 2010, 58:793-798. 10.1016/j.neuropharm.2009.12.007, 2834228, 20026136.
29. Elmarakby AA, Quigley JE, Olearczyk JJ, Sridhar A, Cook AK, Inscho EW, Pollock DM, Imig JD. Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension. Hypertension 2007, 50:1069-1076. 10.1161/HYPERTENSIONAHA.107.098806, 2491337, 17938380.
30. Mirzadegan T, Diehl F, Ebi B, Bhakta S, Polsky I, McCarley D, Mulkins M, Weatherhead GS, Lapierre JM, Dankwardt J, Jr Morgans D, Wilhelm R, Jarnagin K. Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle. J Biol Chem 2000, 275:25562-25571. 10.1074/jbc.M000692200, 10770925.
31. Hagihara H, Toyama K, Yamasaki N, Miyakawa T. Dissection of hippocampal dentate gyrus from adult mouse. J Vis Exp 2009, 33:e1543.
32. Holland PM, Abramson RD, Watson R, Gelfand DH. Detection of specific polymerase chain reaction product by utilizing the 5′-3′exonuclease activity of Thermus aquaticus DNA polymerase. Proc Natl Acad Sci U S A 1991, 88:7276-7280. 10.1073/pnas.88.16.7276, 52277, 1871133.
33. Kralic JE, Ledergerber DA, Fritschy JM. Disruption of the neurogenic potential of the dentate gyrus in a mouse model of temporal lobe epilepsy with focal seizures. Eur J Neurosci 2005, 22:1916-1927. 10.1111/j.1460-9568.2005.04386.x, 16262631.
34. West MJ, Slomianka L, Gundersen HJ. Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator. Anat Rec 1991, 231:482-497. 10.1002/ar.1092310411, 1793176.
35. McCloskey DP, Hintz TM, Pierce JP, Scharfman HE. Stereological methods reveal the robust size and stability of ectopic hilar granule cells after pilocarpine-induced status epilepticus in the adult rat. Eur J Neurosci 2006, 24:2203-2210. 10.1111/j.1460-9568.2006.05101.x, 17042797.
36. West MJ. New stereological methods for counting neurons. Neurobiol Aging 1993, 14:275-285. 10.1016/0197-4580(93)90112-O, 8367009.
37. Mouton PR. Principles and practices of unbiased stereology: an introduction for bioscientists 2002, Baltimore: Johns Hopkins University Press.
38. Wong-Goodrich SJ, Mellott TJ, Glenn MJ, Blusztajn JK, Williams CL. Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus. Neurobiol Dis 2008, 30:255-269. 10.1016/j.nbd.2008.01.008, 2413180, 18353663.
39. Scharfman HE. Functional implications of seizure-induced neurogenesis. Adv Exp Med Biol 2004, 548:192-212. 1839060, 15250595.
40. Scharfman HE, Goodman JH, Sollas AL. Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: functional implications of seizure-induced neurogenesis. J Neurosci 2000, 20:6144-6158.
41. Gong C, Wang TW, Huang HS, Parent JM. Reelin regulates neuronal progenitor migration in intact and epileptic hippocampus. J Neurosci 2007, 27:1803-1811. 10.1523/JNEUROSCI.3111-06.2007, 17314278.
42. Parent JM, Elliott RC, Pleasure SJ, Barbaro NM, Lowenstein DH. Aberrant seizure-induced neurogenesis in experimental temporal lobe epilepsy. Ann Neurol 2006, 59:81-91. 10.1002/ana.20699, 16261566.
43. Sheehan JJ, Zhou C, Gravanis I, Rogove AD, Wu YP, Bogenhagen DF, Tsirka SE. Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice. J Neurosci 2007, 27:1738-1745. 10.1523/JNEUROSCI.4987-06.2007, 17301181.
44. Kalehua AN, Nagel JE, Whelchel LM, Gides JJ, Pyle RS, Smith RJ, Kusiak JW, Taub DD. Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration. Exp Cell Res 2004, 297:197-211. 10.1016/j.yexcr.2004.02.031, 15194436.
45. Tran PB, Banisadr G, Ren D, Chenn A, Miller RJ. Chemokine receptor expression by neural progenitor cells in neurogenic regions of mouse brain. J Comp Neurol 2007, 500:1007-1033. 10.1002/cne.21229, 2758702, 17183554.
46. Hartman NW, Carpentino JE, LaMonica K, Mor DE, Naegele JR, Grabel L. CXCL12-mediated guidance of migrating embryonic stem cell-derived neural progenitors transplanted into the hippocampus. PLoS One 2010, 5:e15856. 10.1371/journal.pone.0015856, 3013129, 21209827.