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Volumn 60, Issue 3, 2013, Pages 455-460

Immune markers of disease severity and treatment response in pediatric acquired aplastic anemia

Author keywords

Aplastic anemia; Immunosuppression; PNH clones

Indexed keywords

CYCLOPHOSPHAMIDE; CYCLOSPORIN A; THYMOCYTE ANTIBODY;

EID: 84872444119     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.24247     Document Type: Article
Times cited : (18)

References (39)
  • 2
    • 0017195338 scopus 로고
    • Aplastic anemia: Presence in human bone marrow of cells that suppress myelopoiesis
    • Kagan WA, Ascensão JA, Pahwa RN, et al. Aplastic anemia: Presence in human bone marrow of cells that suppress myelopoiesis. Proc Natl Acad Sci USA 1976; 73: 2890-2894.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 2890-2894
    • Kagan, W.A.1    Ascensão, J.A.2    Pahwa, R.N.3
  • 3
    • 18744411547 scopus 로고    scopus 로고
    • Aplastic anemia
    • Brodsky RA, Jones RJ. Aplastic anemia. Lancet 2005; 365: 1647-1656.
    • (2005) Lancet , vol.365 , pp. 1647-1656
    • Brodsky, R.A.1    Jones, R.J.2
  • 4
    • 33750628439 scopus 로고    scopus 로고
    • Current concepts in the pathophysiology and treatment of aplastic anemia
    • Young NS, Calado RT, Scheinberg P. Current concepts in the pathophysiology and treatment of aplastic anemia. Blood 2006; 108: 2509-2519.
    • (2006) Blood , vol.108 , pp. 2509-2519
    • Young, N.S.1    Calado, R.T.2    Scheinberg, P.3
  • 5
    • 34548848237 scopus 로고    scopus 로고
    • Deficient CD4+CD25+FoxP3+ T regulatory cells in acquired aplastic anemia
    • Solomou EE, Rezvani K, Mielke S, et al. Deficient CD4+CD25+FoxP3+ T regulatory cells in acquired aplastic anemia. Blood 2007; 110: 1603-1606.
    • (2007) Blood , vol.110 , pp. 1603-1606
    • Solomou, E.E.1    Rezvani, K.2    Mielke, S.3
  • 6
    • 79955833997 scopus 로고    scopus 로고
    • Detection and significance of CD4+ CD25int/high CD127low regulatory T cells in pediatric aplastic anemia
    • Wang XG, Cao YM, Wang XG. Detection and significance of CD4+ CD25int/high CD127low regulatory T cells in pediatric aplastic anemia. Chin J Contemp Pediatr 2011; 13: 292-295.
    • (2011) Chin J Contemp Pediatr , vol.13 , pp. 292-295
    • Wang, X.G.1    Cao, Y.M.2    Wang, X.G.3
  • 7
    • 77952218874 scopus 로고    scopus 로고
    • Expression of regulatory T cells and Foxp3 gene in peripheral blood of children with aplastic anemia
    • Wang XG, Wang XG, Luan B. et al. Expression of regulatory T cells and Foxp3 gene in peripheral blood of children with aplastic anemia. Chin J Contemp Pediatr 2010; 12: 241-243.
    • (2010) Chin J Contemp Pediatr , vol.12 , pp. 241-243
    • Wang, X.G.1    Wang, X.G.2    Luan, B.3
  • 8
    • 77950502501 scopus 로고    scopus 로고
    • Significance of CD4+ CD25+ CD127(low) regulatory T cells and notch1 pathway in the pathogenesis of aplastic anemia
    • Yin XX, Liu CF, Li LZ, et al. Significance of CD4+ CD25+ CD127(low) regulatory T cells and notch1 pathway in the pathogenesis of aplastic anemia. Chin J Hematol 2008; 29: 308-311.
    • (2008) Chin J Hematol , vol.29 , pp. 308-311
    • Yin, X.X.1    Liu, C.F.2    Li, L.Z.3
  • 9
    • 84863229422 scopus 로고    scopus 로고
    • Functional characterization of CD4+ T cells in aplastic anemia
    • Kordasti S, Marsh J, Al-Khan S, et al. Functional characterization of CD4+ T cells in aplastic anemia. Blood 2012; 119: 2033-2043.
    • (2012) Blood , vol.119 , pp. 2033-2043
    • Kordasti, S.1    Marsh, J.2    Al-Khan, S.3
  • 10
    • 84869769578 scopus 로고    scopus 로고
    • Percentages and functions of natural killer cell subsets in peripheral blood of patients with severe aplastic anemia
    • Li ZS, Shao ZH, Fu R, et al. Percentages and functions of natural killer cell subsets in peripheral blood of patients with severe aplastic anemia. Chin Med J 2011; 91: 1084-1087.
    • (2011) Chin Med J , vol.91 , pp. 1084-1087
    • Li, Z.S.1    Shao, Z.H.2    Fu, R.3
  • 11
    • 0027310539 scopus 로고
    • Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria
    • Takeda J, Miyata T, Kawagoe K, et al. Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell 1993; 73: 703-711.
    • (1993) Cell , vol.73 , pp. 703-711
    • Takeda, J.1    Miyata, T.2    Kawagoe, K.3
  • 12
    • 79959689096 scopus 로고    scopus 로고
    • Paroxysmal nocturnal hemoglobinuria from bench to bedside
    • Pu JJ, Brodsky RA. Paroxysmal nocturnal hemoglobinuria from bench to bedside. Clin Transl Sci 2011; 4: 219-224.
    • (2011) Clin Transl Sci , vol.4 , pp. 219-224
    • Pu, J.J.1    Brodsky, R.A.2
  • 13
    • 0033637430 scopus 로고    scopus 로고
    • Dissecting and manipulating the pathway for glycosyl-phosphatidylinositol-anchor biosynthesis
    • Kinoshita T, Inoue N. Dissecting and manipulating the pathway for glycosyl-phosphatidylinositol-anchor biosynthesis. Curr Opin Chem Biol 2000; 4: 632-638.
    • (2000) Curr Opin Chem Biol , vol.4 , pp. 632-638
    • Kinoshita, T.1    Inoue, N.2
  • 14
    • 0021713655 scopus 로고
    • Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes
    • Medof ME, Kinoshita T, Nussenzweig V. Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes. J Exp Med 1984; 160: 1558-1578.
    • (1984) J Exp Med , vol.160 , pp. 1558-1578
    • Medof, M.E.1    Kinoshita, T.2    Nussenzweig, V.3
  • 15
    • 39549112267 scopus 로고    scopus 로고
    • Advances in the diagnosis and therapy of paroxysmal nocturnal hemoglobinuria
    • Brodsky RA. Advances in the diagnosis and therapy of paroxysmal nocturnal hemoglobinuria. Blood Rev 2008; 22: 65-74.
    • (2008) Blood Rev , vol.22 , pp. 65-74
    • Brodsky, R.A.1
  • 16
    • 0025233715 scopus 로고
    • The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9
    • Rollins SA, Sims PJ. The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9. J Immunol 1990; 144: 3478-3483.
    • (1990) J Immunol , vol.144 , pp. 3478-3483
    • Rollins, S.A.1    Sims, P.J.2
  • 17
    • 84872479642 scopus 로고
    • The aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome
    • Lewis SM, Dacie JV. The aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome. Br J Haematol 1967; 85: 1354-1363.
    • (1967) Br J Haematol , vol.85 , pp. 1354-1363
    • Lewis, S.M.1    Dacie, J.V.2
  • 18
    • 58149242770 scopus 로고    scopus 로고
    • Paroxysmal nocturnal hemoglobinuria and myelodysplastic syndromes: clonal expansion of PIG-A mutant hematopoietic cells in bone marrow failure
    • Young NS. Paroxysmal nocturnal hemoglobinuria and myelodysplastic syndromes: clonal expansion of PIG-A mutant hematopoietic cells in bone marrow failure. Haematologica 2009; 94: 3-7.
    • (2009) Haematologica , vol.94 , pp. 3-7
    • Young, N.S.1
  • 19
    • 0033592318 scopus 로고    scopus 로고
    • Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes
    • Dunn D, Tanawattanacharoen P, Boccuni P, et al. Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes. Ann Int Med 1999; 131: 401-408.
    • (1999) Ann Int Med , vol.131 , pp. 401-408
    • Dunn, D.1    Tanawattanacharoen, P.2    Boccuni, P.3
  • 20
    • 0036893544 scopus 로고    scopus 로고
    • Clinical significance of a minor population of paroxysmal nocturnal hemoglobinuria-type cells in bone marrow failure syndrome
    • Wang H, Chuhjo T, Yasue S, et al. Clinical significance of a minor population of paroxysmal nocturnal hemoglobinuria-type cells in bone marrow failure syndrome. Blood 2002; 100: 3897-3902.
    • (2002) Blood , vol.100 , pp. 3897-3902
    • Wang, H.1    Chuhjo, T.2    Yasue, S.3
  • 21
    • 70349218024 scopus 로고    scopus 로고
    • Origin and fate of blood cells deficient in glycosylphosphatidylinositol-anchored protein among patients with bone marrow failure
    • Sugimori C, Mochizuki K. Qi Z. et al. Origin and fate of blood cells deficient in glycosylphosphatidylinositol-anchored protein among patients with bone marrow failure. Br J Haematol 2009; 147: 102-112.
    • (2009) Br J Haematol , vol.147 , pp. 102-112
    • Sugimori, C.1    Mochizuki, K.2    Qi, Z.3
  • 22
    • 32644434385 scopus 로고    scopus 로고
    • Minor population of CD55-CD59-blood cells predicts response to immunosuppressive therapy and prognosis with aplastic anemia
    • Sugimori C, Chuhjo T, Feng X, et al. Minor population of CD55-CD59-blood cells predicts response to immunosuppressive therapy and prognosis with aplastic anemia. Blood 2006; 107: 1308-1314.
    • (2006) Blood , vol.107 , pp. 1308-1314
    • Sugimori, C.1    Chuhjo, T.2    Feng, X.3
  • 23
    • 46949102206 scopus 로고    scopus 로고
    • Clinical impact of HLA-DR15, a minor population of paroxysmal nocturnal hemoglobinuria-type cells, and an aplastic anaemia-associated autoantibody in children with acquired aplastic anemia
    • Yoshida N, Yagasaki H, Takahashi Y, et al. Clinical impact of HLA-DR15, a minor population of paroxysmal nocturnal hemoglobinuria-type cells, and an aplastic anaemia-associated autoantibody in children with acquired aplastic anemia. Br J Haematol 2008; 142: 427-435.
    • (2008) Br J Haematol , vol.142 , pp. 427-435
    • Yoshida, N.1    Yagasaki, H.2    Takahashi, Y.3
  • 24
    • 0041737643 scopus 로고    scopus 로고
    • Polyclonal hematopoiesis maintained in patients with bone marrow failure harboring a minor population of paroxysmal nocturnal hemoglobinuria-type cells
    • Ishiyama K, Chuhjo T, Wang H, et al. Polyclonal hematopoiesis maintained in patients with bone marrow failure harboring a minor population of paroxysmal nocturnal hemoglobinuria-type cells. Blood 2003; 102: 1211-1216.
    • (2003) Blood , vol.102 , pp. 1211-1216
    • Ishiyama, K.1    Chuhjo, T.2    Wang, H.3
  • 25
    • 77954493878 scopus 로고    scopus 로고
    • Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine
    • Scheinberg P, Marte M, Nunez O, et al. Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine. Haematologica 2010; 95: 1075-1080.
    • (2010) Haematologica , vol.95 , pp. 1075-1080
    • Scheinberg, P.1    Marte, M.2    Nunez, O.3
  • 26
    • 79956085129 scopus 로고    scopus 로고
    • Long-term follow-up of clonal evolutions in 802 aplastic anemia patients: a single-center experience
    • Li Y, Li X, Ge M, et al. Long-term follow-up of clonal evolutions in 802 aplastic anemia patients: a single-center experience. Ann Hematol 2011; 90: 529-537.
    • (2011) Ann Hematol , vol.90 , pp. 529-537
    • Li, Y.1    Li, X.2    Ge, M.3
  • 27
    • 77955165492 scopus 로고    scopus 로고
    • Paroxysmal nocturnal hemoglobinuria clones in children with acquired aplastic anemia: a prospective single centre study
    • Timeus F, Crescenzio N, Lorenzati A, et al. Paroxysmal nocturnal hemoglobinuria clones in children with acquired aplastic anemia: a prospective single centre study. Br J Haematol 2010; 150: 483-485.
    • (2010) Br J Haematol , vol.150 , pp. 483-485
    • Timeus, F.1    Crescenzio, N.2    Lorenzati, A.3
  • 28
    • 0029016927 scopus 로고
    • Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia
    • Rosenfeld SJ, Kimball J, Vining D, et al. Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia. Blood 1995; 85: 3058-3065.
    • (1995) Blood , vol.85 , pp. 3058-3065
    • Rosenfeld, S.J.1    Kimball, J.2    Vining, D.3
  • 29
    • 56049083968 scopus 로고    scopus 로고
    • Long-term outcome of pediatric patients with severe aplastic anemia treated with antithymocyte globulin and cyclosporine
    • Scheinberg P, Wu CO, Nunez O, et al. Long-term outcome of pediatric patients with severe aplastic anemia treated with antithymocyte globulin and cyclosporine. J Pediatr 2008; 153: 814-819.
    • (2008) J Pediatr , vol.153 , pp. 814-819
    • Scheinberg, P.1    Wu, C.O.2    Nunez, O.3
  • 30
    • 70449572587 scopus 로고    scopus 로고
    • MRI findings in Aplastic Anemia
    • De Mola RL, Kurre P, MRI findings in Aplastic Anemia. Am J Hematol 2009; 84: 754.
    • (2009) Am J Hematol , vol.84 , pp. 754
    • De Mola, R.L.1    Kurre, P.2
  • 31
    • 33646508735 scopus 로고    scopus 로고
    • A cohort study of the nature of paroxysmal nocturnal hemoglobinuria clones and PIG-A mutations in patients with aplastic anemia
    • Wanachiwanawin W, Siripanyaphinyo U, Piyawattanasakul N, et al. A cohort study of the nature of paroxysmal nocturnal hemoglobinuria clones and PIG-A mutations in patients with aplastic anemia. Eur J Haematol 2006; 76: 502-509.
    • (2006) Eur J Haematol , vol.76 , pp. 502-509
    • Wanachiwanawin, W.1    Siripanyaphinyo, U.2    Piyawattanasakul, N.3
  • 32
    • 79959511958 scopus 로고    scopus 로고
    • Natural history of paroxysmal nocturnal hemoglobinuria clones in patients presenting as aplastic anemia
    • Pu JJ, Muhkina G, Wang H, et al. Natural history of paroxysmal nocturnal hemoglobinuria clones in patients presenting as aplastic anemia. Eur J Haematol 2011; 87: 37-45.
    • (2011) Eur J Haematol , vol.87 , pp. 37-45
    • Pu, J.J.1    Muhkina, G.2    Wang, H.3
  • 33
    • 84979824002 scopus 로고    scopus 로고
    • In vitro activation of bone marrow natural killer T cells of aplastic anemia
    • Wang YX, Xu CG, Ran JL, et al. In vitro activation of bone marrow natural killer T cells of aplastic anemia. Chin J Hematol 2010; 31: 536-539.
    • (2010) Chin J Hematol , vol.31 , pp. 536-539
    • Wang, Y.X.1    Xu, C.G.2    Ran, J.L.3
  • 34
    • 7344242596 scopus 로고    scopus 로고
    • Relapse and clonal disease in children with aplastic anemia (AA) after immunosuppressive therapy (IST): the SAA 94 experience
    • Furher M, Burdach S, Ebell W, et al. Relapse and clonal disease in children with aplastic anemia (AA) after immunosuppressive therapy (IST): the SAA 94 experience. Klinische Padiatrie 1998; 210: 173-179.
    • (1998) Klinische Padiatrie , vol.210 , pp. 173-179
    • Furher, M.1    Burdach, S.2    Ebell, W.3
  • 35
    • 0034665668 scopus 로고    scopus 로고
    • Immunosuppressive therapy using antithymocyte globulin, cyclosporine, and danazol with or without human granulocyte colony-stimulating factor in children with acquired aplastic anemia
    • Kojima S, Hibi S, Kosaka Y, et al. Immunosuppressive therapy using antithymocyte globulin, cyclosporine, and danazol with or without human granulocyte colony-stimulating factor in children with acquired aplastic anemia. Blood 2000; 96: 2049-2054.
    • (2000) Blood , vol.96 , pp. 2049-2054
    • Kojima, S.1    Hibi, S.2    Kosaka, Y.3
  • 36
    • 58149090759 scopus 로고    scopus 로고
    • Predicting response to immunosuppressive therapy and survival in severe aplastic anaemia
    • Sheinberg P, Wu CO, Nunez O, et al. Predicting response to immunosuppressive therapy and survival in severe aplastic anaemia. British J Haematol 2008; 1144: 206-216.
    • (2008) British J Haematol , vol.1144 , pp. 206-216
    • Sheinberg, P.1    Wu, C.O.2    Nunez, O.3
  • 37
    • 37249068118 scopus 로고    scopus 로고
    • Cyclosporine A response and dependence in children with acquired aplastic anaemia: a multicentre retrospective study with long-term observation follow-up
    • Saracco P, Quarello P, Iori AP, et al. Cyclosporine A response and dependence in children with acquired aplastic anaemia: a multicentre retrospective study with long-term observation follow-up. Br J Haematol 2008; 140: 197-205.
    • (2008) Br J Haematol , vol.140 , pp. 197-205
    • Saracco, P.1    Quarello, P.2    Iori, A.P.3
  • 38
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nature Immunol 2005; 6: 345-352.
    • (2005) Nature Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 39
    • 79958279325 scopus 로고    scopus 로고
    • In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche
    • Fujisaki J, Wu J, Carlson AL, et al. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature 2011; 474: 216-220.
    • (2011) Nature , vol.474 , pp. 216-220
    • Fujisaki, J.1    Wu, J.2    Carlson, A.L.3


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