The Anrep effect: 100 years later

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 2, 2013, Pages

  Cingolani, Horacio E ^a   Pérez, Néstor G ^a   Cingolani, Oscar H ^b   Ennis, Irene L ^a  

^a UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^b JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Angiotensin ii; Nhe1; Slow force response; Stretch; Transactivation

Indexed keywords

ALDOSTERONE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CALCIUM ION; ENDOTHELIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; MINERALOCORTICOID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN P90; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SODIUM CALCIUM EXCHANGE PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6;

ANREP EFFECT; AUTOCRINE EFFECT; GENE SILENCING; HEART FAILURE; HEART HEMODYNAMICS; HEART HYPERTROPHY; HEART MUSCLE; HEART MUSCLE CELL; HUMAN; MITOCHONDRION; MUSCLE STRETCHING; NONHUMAN; PARACRINE SIGNALING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVIEW; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STRETCH RECEPTOR; TRANSACTIVATION;

ANIMALS; AUTOCRINE COMMUNICATION; CALCIUM; CATION TRANSPORT PROTEINS; EXCITATION CONTRACTION COUPLING; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MECHANORECEPTORS; MECHANOTRANSDUCTION, CELLULAR; MODELS, CARDIOVASCULAR; MUSCLE STRENGTH; MYOCARDIAL CONTRACTION; MYOCARDIUM; PARACRINE COMMUNICATION; REFLEX, STRETCH; RNA INTERFERENCE; SODIUM-HYDROGEN ANTIPORTER;

EID: 84872407462     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00508.2012     Document Type: Review

References (82)

1. + i-independent pathways. Hypertension 45: 288-293, 2005.
2. Allen DG, Kurihara S. The effects of muscle length on intracellular calcium transients in mammalian cardiac muscle. J Physiol 327: 79-94, 1982.
3. 2+ transient that follow stretch of cardiac muscle: a possible explanation of the Anrep effect. Circ Res 85: 716-722, 1999.
4. +-exchanger attenuates cardiac hypertrophy and prevents cellular remodeling in heart failure. Cardiovasc Res 65: 83-92, 2005.
5. Barton M, Shaw S, d'Uscio LV, Moreau P, Luscher TF. Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: role of ETA receptors for endothelin regulation. Biochem Biophys Res Commun 238: 861-865, 1997.
6. + regulation in cardiac myocytes. Cardiovasc Res 57: 897-912, 2003.
7. Bluhm WF, Lew WY. Sarcoplasmic reticulum in cardiac length-dependent activation in rabbits. Am J Physiol Heart Circ Physiol 269: H965-H972, 1995.
8. Bluhm WF, Lew WY, Garfinkel A, McCulloch AD. Mechanisms of length history-dependent tension in an ionic model of the cardiac myocyte. Am J Physiol Heart Circ Physiol 274: H1032-H1040, 1998.
9. Brandes RP. Triggering mitochondrial radical release: a new function for NADPH oxidases. Hypertension 45: 847-848, 2005.
10. - current elicited by beta1 integrin stretch in rabbit ventricular myocytes. J Gen Physiol 124: 273-287, 2004.
11. + exchange and stretchactivated channels underlies the slow inotropic response to stretch in myocytes and muscle from the rat heart. J Physiol 559: 205-214, 2004.
12. Caldiz CI, Diaz RG, Nolly MB, Chiappe de Cingolani GE, Ennis IL, Cingolani HE, Perez NG. Mineralocorticoid receptor activation is crucial in the signalling pathway leading to the Anrep effect. J Physiol 589: 6051-6061, 2011.
13. Caldiz CI, Garciarena CD, Dulce RA, Novaretto LP, Yeves AM, Ennis IL, Cingolani HE, Chiappe de Cingolani G, Perez NG. Mitochondrial reactive oxygen species activate the slow force response to stretch in feline myocardium. J Physiol 584: 895-905, 2007.
14. Cingolani HE, Alvarez BV, Ennis IL, Camilion de Hurtado MC. Stretch-induced alkalinization of feline papillary muscle: an autocrineparacrine system. Circ Res 83: 775-780, 1998.
15. - exchange on the slow force response to myocardial stretch. Circ Res 93: 1082-1088, 2003.
16. Cingolani HE, Perez NG, Camilion de Hurtado MC. An autocrine/ paracrine mechanism triggered by myocardial stretch induces changes in contractility. News Physiol Sci 16: 88-91, 2001.
17. Cingolani HE, Villa-Abrille MC, Cornelli M, Nolly A, Ennis IL, Garciarena C, Suburo AM, Torbidoni V, Correa MV, Camilionde Hurtado MC, Aiello EA. The positive inotropic effect of angiotensin II: role of endothelin-1 and reactive oxygen species. Hypertension 47: 727-734, 2006.
18. Cingolani OH, Kirk JA, Seo K, Koitabashi N, Lee DI, Ramirez- Correa G, Bedja D, Barth AS, Moens AL, Kass DA. Thrombospondin-4 is required for stretch-mediated contractility augmentation in cardiac muscle. Circ Res 109: 1410-1414, 2011.
19. Cingolani OH, Perez NG, Ennis IL, Alvarez MC, Mosca SM, Schinella GR, Escudero EM, Console G, Cingolani HE. In vivo key role of reactive oxygen species and NHE-1 activation in determining excessive cardiac hypertrophy. Pflügers Arch 462: 733-743, 2011.
20. Chai W, Hoedemaekers Y, van Schaik RH, van Fessem M, Garrelds IM, Saris JJ, Dooijes D, ten Cate FJ, Kofflard MM, Danser AH. Cardiac aldosterone in subjects with hypertrophic cardiomyopathy. J Renin Angiotensin Aldosterone Syst 7: 225-230, 2006.
21. Chua BH, Chua CC, Diglio CA, Siu BB. Regulation of endothelin-1 mRNA by angiotensin II in rat heart endothelial cells. Biochim Biophys Acta 1178: 201-206, 1993.
22. + exchanger via transactivation of the epidermal growth factor receptor. Hypertension 58: 912-919, 2011.
23. - exchanger by angiotensin II is mediated by endogenous endothelin. Circ Res 86: 622-627, 2000.
24. Dohi Y, Hahn AW, Boulanger CM, Buhler FR, Luscher TF. Endothelin stimulated by angiotensin II augments contractility of spontaneously hypertensive rat resistance arteries. Hypertension 19: 131-137, 1992.
25. + exchanger-1 (NHE-1) inhibition. Can J Physiol Pharmacol 85: 301-310, 2007.
26. Fabiato A, Fabiato F. Effects of pH on the myofilaments and the sarcoplasmic reticulum of skinned cells from cardiace and skeletal muscles. J Physiol 276: 233-255, 1978.
27. Fujisaki H, Ito H, Hirata Y, Tanaka M, Hata M, Lin M, Adachi S, Akimoto H, Marumo F, Hiroe M. Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin- 1 gene expression. J Clin Invest 96: 1059-1065, 1995.
28. Funder JW. The nongenomic actions of aldosterone. Endocr Rev 26: 313-321, 2005.
29. + exchanger- 1 inhibitors decrease myocardial superoxide production via direct mitochondrial action. J Appl Physiol 105: 1706-1713, 2008.
30. Gomez-Sanchez EP, Ahmad N, Romero DG, Gomez-Sanchez CE. Origin of aldosterone in the rat heart. Endocrinology 145: 4796-4802, 2004.
31. Grossmann C, Gekle M. New aspects of rapid aldosterone signaling. Mol Cell Endocrinol 308: 53-62, 2009.
32. Guharay F, Sachs F. Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle. J Physiol 352: 685-701, 1984.
33. Hongo K, White E, Orchard CH. Effect of stretch on contraction and the Ca2 transient in ferret ventricular muscles during hypoxia and acidosis. Am J Physiol Cell Physiol 269: C690-C697, 1995.
34. Imai T, Hirata Y, Emori T, Yanagisawa M, Masaki T, Marumo F. Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells. Hypertension 19: 753-757, 1992.
35. Ito H, Hirata Y, Adachi S, Tanaka M, Tsujino M, Koike A, Nogami A, Murumo F, Hiroe M. Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest 92: 398-403, 1993.
36. Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchiyama S, Sasaki H, Masushige S, Gotoh Y, Nishida E, Kawashima H, Metzger D, Chambon P. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270: 1491-1494, 1995.
37. 2+ concentration after length changes in isolated rat ventricular trabeculae. J Physiol 506: 431-444, 1998.
38. Kimura S, Zhang GX, Nishiyama A, Shokoji T, Yao L, Fan YY, Rahman M, Abe Y. Mitochondria-derived reactive oxygen species and vascular MAP kinases: comparison of angiotensin II and diazoxide. Hypertension 45: 438-444, 2005.
39. Kockskamper J, Khafaga M, Grimm M, Elgner A, Walther S, Kockskamper A, von Lewinski D, Post H, Grossmann M, Dorge H, Gottlieb PA, Sachs F, Eschenhagen T, Schondube FA, Pieske B. Angiotensin II and myosin light-chain phosphorylation contribute to the stretch-induced slow force response in human atrial myocardium. Cardiovasc Res 79: 642-651, 2008.
40. Kockskamper J, von Lewinski D, Khafaga M, Elgner A, Grimm M, Eschenhagen T, Gottlieb PA, Sachs F, Pieske B. The slow force response to stretch in atrial and ventricular myocardium from human heart: functional relevance and subcellular mechanisms. Prog Biophys Mol Biol 97: 250-267, 2008.
41. Kojima M, Shiojima I, Yamazaki T, Komuro I, Zou Z, Wang Y, Mizuno T, Ueki K, Tobe K, Kadowaki T. Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro. Circulation 89: 2204-2211, 1994.
42. + exchanger with cariporide abolishes stretch-induced calcium but not sodium accumulation in mouse ventricular myocytes. Cell Calcium 37: 69-80, 2005.
43. Lemarie CA, Paradis P, Schiffrin EL. New insights on signaling cascades induced by cross-talk between angiotensin II and aldosterone. J Mol Med 86: 673-678, 2008.
44. Lemarie CA, Simeone SM, Nikonova A, Ebrahimian T, Deschenes ME, Coffman TM, Paradis P, Schiffrin EL. Aldosterone-induced activation of signaling pathways requires activity of angiotensin type 1a receptors. Circ Res 105: 852-859, 2009.
45. Leri A, Claudio PP, Li Q, Wang X, Reiss K, Wang S, Malhotra A, Kajstura J, Anversa P. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local reninangiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest 101: 1326-1342, 1998.
46. Liang F, Gardner DG. Autocrine/paracrine determinants of strain-activated brain natriuretic peptide gene expression in cultured cardiac myocytes. J Biol Chem 273: 14612-14619, 1998.
47. +]i, and pHi in rabbit myocardium-a mechanism for the slow force response. Cardiovasc Res 68: 454-463, 2005.
48. Maroto R, Raso A, Wood TG, Kurosky A, Martinac B, Hamill OP. TRPC1 forms the stretch-activated cation channel in vertebrate cells. Nat Cell Biol 7: 179-185, 2005.
49. Mattiazzi AR, Cingolani HE, de Castuma ES. Relationship between calcium and hydrogen ions in heart muscle. Am J Physiol Heart Circ Physiol 237: H497-H503, 1979.
50. Mihailidou AS, Loan Le TY, Mardini M, Funder JW. Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction. Hypertension 54: 1306-1312, 2009.
51. Muller DN, Mullally A, Dechend R, Park JK, Fiebeler A, Pilz B, Loffler BM, Blum-Kaelin D, Masur S, Dehmlow H, Aebi JD, Haller H, Luft FC. Endothelin-converting enzyme inhibition ameliorates angiotensin II-induced cardiac damage. Hypertension 40: 840-846, 2002.
52. Nagase M, Ayuzawa N, Kawarazaki W, Ishizawa K, Ueda K, Yoshida S, Fujita T. Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes: role of small GTPase Rac1. Hypertension 59: 500-506, 2012.
53. Niederer SA, Smith NP. A mathematical model of the slow force response to stretch in rat ventricular myocytes. Biophys J 92: 4030-4044, 2007.
54. Orchard CH, Kentish JC. Effects of changes of pH on the contractile function of cardiac muscle. Am J Physiol Cell Physiol 258: C967-C981, 1990.
55. Ortiz MC, Sanabria E, Manriquez MC, Romero JC, Juncos LA. Role of endothelin and isoprostanes in slow pressor responses to angiotensin II. Hypertension 37: 505-510, 2001.
56. Parmley WW, Chuck L. Length-dependent changes in myocardial contractile state. Am J Physiol 224: 1195-1199, 1973.
57. 2+ exchange after myocardial stretch: underlying mechanism of the slow force response. Circ Res 88: 376-382, 2001.
58. Perez NG, Nolly MB, Roldan MC, Villa-Abrille MC, Cingolani E, Portiansky EL, Alvarez BV, Ennis IL, Cingolani HE. Silencing of NHE-1 blunts the slow force response to myocardial stretch. J Appl Physiol 111: 874-880, 2011.
59. 2+ exchange by endothelin release. Cardiovasc Res 60: 589-597, 2003.
60. 2+ release in cardiomyocytes. Nat Cell Biol 3: 867-873, 2001.
61. Prosser BL, Ward CW, Lederer WJ. X-ROS signaling: rapid mechanochemo transduction in heart. Science 333: 1440-1445, 2011.
62. Rajagopalan S, Laursen JB, Borthayre A, Kurz S, Keiser J, Haleen S, Giaid A, Harrison DG. Role for endothelin-1 in angiotensin II-mediated hypertension. Hypertension 30: 29-34, 1997.
63. Rosenblueth A, Alanis J, Lopez E, Rubio R. The adaptation of ventricular muscle to different circulatory conditions. Arch Int Physiol Biochim 67: 358-373, 1959.
64. + exchange in neonatal rat cardiac myocytes. Circ Res 82: 1053-1062, 1998.
65. Sadoshima J, Xu Y, Slayter HS, Izumo S. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 75: 977-984, 1993.
66. Sarnoff SJ, Mitchell JH, Gilmore JP, Remensnyder JP. Homeometric autoregulation in the heart. Circ Res 8: 1077-1091, 1960.
67. Silvestre JS, Robert V, Heymes C, Aupetit-Faisant B, Mouas C, Moalic JM, Swynghedauw B, Delcayre C. Myocardial production of aldosterone and corticosterone in the rat. Physiological regulation. J Biol Chem 273: 4883-4891, 1998.
68. Spassova MA, Hewavitharana T, Xu W, Soboloff J, Gill DL. A common mechanism underlies stretch activation and receptor activation of TRPC6 channels. Proc Natl Acad Sci USA 103: 16586-16591, 2006.
69. Thomas RC. Cell growth factors. Bicarbonate and pHi response. Nature 337: 601, 1989.
70. Villa-Abrille MC, Caldiz CI, Ennis IL, Nolly MB, Casarini MJ, Chiappe de Cingolani GE, Cingolani HE, Perez NG. The Anrep effect requires transactivation of the epidermal growth factor receptor. J Physiol 588: 1579-1590, 2010.
71. Villa-Abrille MC, Cingolani E, Cingolani HE, Alvarez BV. Silencing of cardiac mitochondrial NHE1 prevents mitochondrial permeability transition pore opening. Am J Physiol Heart Circ Physiol 300: H1237-H1251, 2011.
72. von Anrep G. On the part played by the suprarenals in the normal vascular reactions of the body. J Physiol 45: 307-317, 1912.
73. von Lewinski D, Stumme B, Fialka F, Luers C, Pieske B. Functional relevance of the stretch-dependent slow force response in failing human myocardium. Circ Res 94: 1392-1398, 2004.
74. Wang H, Shimosawa T, Matsui H, Kaneko T, Ogura S, Uetake Y, Takenaka K, Yatomi Y, Fujita T. Paradoxical mineralocorticoid receptor activation and left ventricular diastolic dysfunction under high oxidative stress conditions. J Hypertens 26: 1453-1462, 2008.
75. Ward ML, Williams IA, Chu Y, Cooper PJ, Ju YK, Allen DG. Stretch-activated channels in the heart: contributions to length-dependence and to cardiomyopathy. Prog Biophys Mol Biol 97: 232-249, 2008.
76. Williams GH. Genetic factors associated with volume-sensitive hypertension. Mol Cell Endocrinol 217: 41-44, 2004.
77. Wu X, Eder P, Chang B, Molkentin JD. TRPC channels are necessary mediators of pathologic cardiac hypertrophy. Proc Natl Acad Sci USA 107: 7000-7005, 2010.
78. Zeng T, Bett GC, Sachs F. Stretch-activated whole cell currents in adult rat cardiac myocytes. Am J Physiol Heart Circ Physiol 278: H548-H557, 2000.
79. Zhai P, Galeotti J, Liu J, Holle E, Yu X, Wagner T, Sadoshima J. An angiotensin II type 1 receptor mutant lacking epidermal growth factor receptor transactivation does not induce angiotensin II-mediated cardiac hypertrophy. Circ Res 99: 528-536, 2006.
80. 2+ exchanger current in guinea-pig isolated ventricular myocytes. Br J Pharmacol 130: 485-488, 2000.
81. Zorov DB, Filburn CR, Klotz LO, Zweier JL, Sollott SJ. Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J Exp Med 192: 1001-1014, 2000.
82. Zou Y, Akazawa H, Qin Y, Sano M, Takano H, Minamino T, Makita N, Iwanaga K, Zhu W, Kudoh S, Toko H, Tamura K, Kihara M, Nagai T, Fukamizu A, Umemura S, Iiri T, Fujita T, Komuro I. Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol 6: 499-506, 2004.