The DNA methyltransferase inhibitor zebularine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo

Biochemical and Biophysical Research Communications

Volumn 430, Issue 1, 2013, Pages 250-255

  Tan, Wei ^a   Zhou, Wei ^a   Yu, Hong gang ^a   Luo, He Sheng ^a   Shen, Lei ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Apoptosis; Gastric cancer; Mitochondria; Zebularine

Indexed keywords

CASPASE 3; NITROBLUE TETRAZOLIUM; PROTEIN BAX; PROTEIN BCL 2; ZEBULARINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL PROLIFERATION; DRUG EFFECT; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; STOMACH CANCER; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYTIDINE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; ENZYME INHIBITORS; HUMANS; MICE; MICE, NUDE; MITOCHONDRIA; NEOPLASM TRANSPLANTATION; STOMACH NEOPLASMS;

EID: 84872406394     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.10.143     Document Type: Article

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