Angiotensin AT2 Receptor Contributes towards Gender Bias in Weight Gain

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Samuel, Preethi ^a   Khan, Mohammad Azhar ^a   Nag, Sourashish ^a   Inagami, Tadashi ^b   Hussain, Tahir ^a  

^a UNIVERSITY OF HOUSTON   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 2 RECEPTOR; ESTRADIOL; ESTROGEN; FATTY ACID; INSULIN; LIOTHYRONINE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; ESTROGEN BLOOD LEVEL; ESTROGEN URINE LEVEL; FAT MASS; FATTY ACID BLOOD LEVEL; FEMALE; GENDER BIAS; HORMONAL REGULATION; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; KNOCKOUT MOUSE; LIOTHYRONINE BLOOD LEVEL; LIPID DIET; LIPID LIVER LEVEL; LIPID METABOLISM; MALE; MOUSE; NONHUMAN; PROTECTION; PROTEIN FUNCTION; SEX DIFFERENCE; WEIGHT GAIN; WILD TYPE;

ADIPOSE TISSUE; ANIMALS; DIET, HIGH-FAT; ENERGY INTAKE; ESTRADIOL; FATTY ACIDS, NONESTERIFIED; FEEDING BEHAVIOR; FEMALE; GLUCOSE TOLERANCE TEST; GONADS; HUMANS; INSULIN; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGAN SIZE; RECEPTOR, ANGIOTENSIN, TYPE 2; SEX CHARACTERISTICS; TRIGLYCERIDES; TRIIODOTHYRONINE; WEIGHT GAIN;

ANIMALIA; MUS;

EID: 84872398693     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048425     Document Type: Article

References (52)

1. Lusis AJ, Attie AD, Reue K, (2008) Metabolic syndrome: from epidemiology to systems biology. Nat Rev Genet 9: 819-830.
2. Clasen R, Schupp M, Foryst-Ludwig A, Sprang C, Clemenz M, et al. (2005) PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin. Hypertension 46: 137-143.
3. Erbe DV, Gartrell K, Zhang YL, Suri V, Kirincich SJ, et al. (2006) Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists. Vascul Pharmacol 45: 154-162.
4. Jones BH, Standridge MK, Moustaid N, (1997) Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells. Endocrinology 138: 1512-1519.
5. Wang CH, Li F, Takahashi N, (2010) The renin angiotensin system and the metabolic syndrome. Open Hypertens J 3: 1-13.
6. Kouyama R, Suganami T, Nishida J, Tanaka M, Toyoda T, et al. (2005) Attenuation of diet-induced weight gain and adiposity through increased energy expenditure in mice lacking angiotensin II type 1a receptor. Endocrinology 146: 3481-3489.
7. Henriksen EJ, (2007) Improvement of insulin sensitivity by antagonism of the renin-angiotensin system. Am J Physiol Regul Integr Comp Physiol 293: R974-980.
8. Yvan-Charvet L, Even P, Bloch-Faure M, Guerre-Millo M, Moustaid-Moussa N, et al. (2005) Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance. Diabetes 54: 991-999.
9. Ainslie DA, Morris MJ, Wittert G, Turnbull H, Proietto J, et al. (2001) Estrogen deficiency causes central leptin insensitivity and increased hypothalamic neuropeptide Y. Int J Obes Relat Metab Disord. 25: 1680-1688.
10. Yvan-Charvet L, Even P, Lamande N, Ferre P, Quignard-Boulange A, (2006) Prevention of adipose tissue depletion during food deprivation in angiotensin type 2 receptor-deficient mice. Endocrinology 147: 5078-5086.
11. Yvan-Charvet L, Massiera F, Lamande N, Ailhaud G, Teboul M, et al. (2009) Deficiency of angiotensin type 2 receptor rescues obesity but not hypertension induced by overexpression of angiotensinogen in adipose tissue. Endocrinology 150: 1421-1428.
12. Sandberg K, Ji H, (2008) Why can't a woman be more like a man?: Is the angiotensin type 2 receptor to blame or to thank? Hypertension 52: 615-617.
13. Miller JA, Anacta LA, Cattran DC, (1999) Impact of gender on the renal response to angiotensin II. Kidney Int 55: 278-285.
14. Silbiger SR, Neugarten J, (1995) The impact of gender on the progression of chronic renal disease. Am J Kidney Dis 25: 515-533.
15. Sampson AK, Widdop RE, Denton KM, (2008) Sex-differences in circadian blood pressure variations in response to chronic angiotensin II infusion in rats. Clin Exp Pharmacol Physiol 35: 391-395.
16. Armando I, Jezova M, Juorio AV, Terron JA, Falcon-Neri A, et al. (2002) Estrogen upregulates renal angiotensin II AT(2) receptors. Am J Physiol Renal Physiol 283: F934-943.
17. Louet JF, LeMay C, Mauvais-Jarvis F, (2004) Antidiabetic actions of estrogen: insight from human and genetic mouse models. Curr Atheroscler Rep 6: 180-185.
18. Sampson AK, Moritz KM, Jones ES, Flower RL, Widdop RE, et al. (2008) Enhanced angiotensin II type 2 receptor mechanisms mediate decreases in arterial pressure attributable to chronic low-dose angiotensin II in female rats. Hypertension 52: 666-671.
19. Dole VP, (1956) A relation between non-esterified fatty acids in plasma and the metabolism of glucose. J Clin Invest 35: 150-154.
20. Randle PJ, Garland PB, Hales CN, Newsholme EA, (1963) The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1: 785-789.
21. Black AE, Goldberg GR, Jebb SA, Livingstone MB, Cole TJ, et al. (1991) Critical evaluation of energy intake data using fundamental principles of energy physiology: 2. Evaluating the results of published surveys. Eur J Clin Nutr 45: 583-599.
22. Ichiki T, Labosky PA, Shiota C, Okuyama S, Imagawa Y, et al. (1995) Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor. Nature 377: 748-750.
23. Rosenbaum M, Hirsch J, Murphy E, Leibel RL, (2000) Effects of changes in body weight on carbohydrate metabolism, catecholamine excretion, and thyroid function. Am J Clin Nutr 71: 1421-1432.
24. Riant E, Waget A, Cogo H, Arnal JF, Burcelin R, et al. (2009) Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice. Endocrinology 150: 2109-2117.
25. Baiardi G, Macova M, Armando I, Ando H, Tyurmin D, et al. (2005) Estrogen upregulates renal angiotensin II AT1 and AT2 receptors in the rat. Regul Pept 124: 7-17.
26. Yoshimura Y, Karube M, Aoki H, Oda T, Koyama N, et al. (1996) Angiotensin II induces ovulation and oocyte maturation in rabbit ovaries via the AT2 receptor subtype. Endocrinology 137: 1204-1211.
27. Kotani K, Sakane N, Saiga K, Tsuzaki K, Sano Y, et al. (2007) The angiotensin II type 2 receptor gene polymorphism and body mass index in healthy Japanese women. Ann Clin Biochem 44: 83-85.
28. Cinti S, (2005) The adipose organ. Prostaglandins Leukot Essent Fatty Acids 73: 9-15.
29. Bachmanov AA, Reed DR, Tordoff MG, Price RA, Beauchamp GK, (2001) Nutrient preference and diet-induced adiposity in C57BL/6ByJ and 129P3/J mice. Physiol Behav 72: 603-613.
30. Kissebah AH, Krakower GR, (1994) Regional adiposity and morbidity. Physiol Rev 74: 761-811.
31. Thomas HV, Reeves GK, Key TJ, (1997) Endogenous estrogen and postmenopausal breast cancer: a quantitative review. Cancer Causes Control 8: 922-928.
32. Simpson E, Rubin G, Clyne C, Robertson K, O'Donnell L, et al. (1999) Local estrogen biosynthesis in males and females. Endocr Relat Cancer 6: 131-137.
33. Bruch HR, Wolf L, Budde R, Romalo G, Schweikert HU, (1992) Androstenedione metabolism in cultured human osteoblast-like cells. J Clin Endocrinol Metab 75: 101-105.
34. Naftolin F, Ryan KJ, Davies IJ, Reddy VV, Flores F, et al. (1975) The formation of estrogens by central neuroendocrine tissues. Recent Prog Horm Res 31: 295-319.
35. Heine PA, Taylor JA, Iwamoto GA, Lubahn DB, Cooke PS, (2000) Increased adipose tissue in male and female estrogen receptor-alpha knockout mice. Proc Natl Acad Sci U S A 97: 12729-12734.
36. Nitta H, Bunick D, Hess RA, Janulis L, Newton SC, et al. (1993) Germ cells of the mouse testis express P450 aromatase. Endocrinology 132: 1396-1401.
37. Hemsell DL, Grodin JM, Brenner PF, Siiteri PK, MacDonald PC, (1974) Plasma precursors of estrogen. II. Correlation of the extent of conversion of plasma androstenedione to estrone with age. J Clin Endocrinol Metab 38: 476-479.
38. Grumbach MM, Auchus RJ, (1999) Estrogen: consequences and implications of human mutations in synthesis and action. J Clin Endocrinol Metab 84: 4677-4694.
39. Poehlman ET, Tchernof A, (1998) Traversing the menopause: changes in energy expenditure and body composition. Coron Artery Dis 9: 799-803.
40. Engeli S, Gorzelniak K, Kreutz R, Runkel N, Distler A, et al. (1999) Co-expression of renin-angiotensin system genes in human adipose tissue. J Hypertens 17: 555-560.
41. Lu H, Boustany-Kari CM, Daugherty A, Cassis LA, (2007) Angiotensin II increases adipose angiotensinogen expression. Am J Physiol Endocrinol Metab 292: E1280-1287.
42. Boden G, Shulman GI, (2002) Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur J Clin Invest 32Suppl 3: 14-23.
43. Boden G, (1997) Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 46: 3-10.
44. Delarue J, Magnan C, (2007) Free fatty acids and insulin resistance. Curr Opin Clin Nutr Metab Care 10: 142-148.
45. Shimizu H, Shimomura Y, Nakanishi Y, Futawatari T, Ohtani K, et al. (1997) Estrogen increases in vivo leptin production in rats and human subjects. J Endocrinol 154: 285-292.
46. Gao Q, Horvath TL, (2008) Cross-talk between estrogen and leptin signaling in the hypothalamus. Am J Physiol Endocrinol Metab 294: E817-826.
47. Pelleymounter MA, Baker MB, McCaleb M, (1999) Does estradiol mediate leptin's effects on adiposity and body weight? Am J Physiol 276: E955-963.
48. Spiegelman BM, (1998) PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. Diabetes 47: 507-514.
49. Kim S, Dugail I, Standridge M, Claycombe K, Chun J, et al. (2001) Angiotensin II-responsive element is the insulin-responsive element in the adipocyte fatty acid synthase gene: role of adipocyte determination and differentiation factor 1/sterol-regulatory-element-binding protein 1c. Biochem J 357: 899-904.
50. Xu H, Barnes GT, Yang Q, Tan G, Yang D, et al. (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112: 1821-1830.
51. Spiegelman BM, Puigserver P, Wu Z, (2000) Regulation of adipogenesis and energy balance by PPARgamma and PGC-1. Int J Obes Relat Metab Disord 24Suppl 4: S8-10.
52. Olefsky JM, (2000) Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists. J Clin Invest 106: 467-472.