Tumor necrosis factor-alpha potentiates the cytotoxicity of amiodarone in hepa1c1c7 cells: Roles of caspase activation and oxidative stress

Toxicological Sciences

Volumn 131, Issue 1, 2013, Pages 164-178

  Lu, Jingtao ^a,b   Miyakawa, Kazuhisa ^b   Roth, Robert A ^b,c   Ganey, Patricia E ^b,c  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Amiodarone; Caspase; Lipid peroxidation; Tumor necrosis factor alpha

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; AMIODARONE; ASCORBIC ACID; CASPASE; CASPASE 3; CASPASE 7; CASPASE 9; CASPASE INHIBITOR; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; TROLOX C; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL DEATH; CYTOTOXICITY; DRUG POTENTIATION; HEPATOMA CELL; HUMAN; IN VITRO STUDY; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS;

AMIODARONE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE INHIBITORS; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; DNA BREAKS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME ACTIVATION; IN SITU NICK-END LABELING; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 84872397813     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs289     Document Type: Article

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