The nuclear factor κB inhibitor (E)-2-fluoro-4′-methoxystilbene inhibits firefly luciferase

Bioscience Reports

Volumn 32, Issue 6, 2012, Pages 531-537

  Braeuning, Albert ^a   Vetter, Silvia ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Firefly; Luciferase inhibitor; Nuclear factor B; Reporter gene assay; Resveratrol

Indexed keywords

2 FLUORO 4' METHOXYSTILBENE; 25 HYDROXYVITAMIN D; ADENOSINE TRIPHOSPHATE; BETA CATENIN; FIREFLY LUCIFERASE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERIN; RESVERATROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; FIREFLY; IN VITRO STUDY; MOUSE; NONHUMAN; PHOTINUS PYRALIS; REAL TIME POLYMERASE CHAIN REACTION; RENILLA; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE, TUMOR; COPEPODA; FIREFLIES; INHIBITORY CONCENTRATION 50; LUCIFERASES; LUCIFERASES, FIREFLY; LUCIFERASES, RENILLA; LUMINESCENT AGENTS; MICE; NF-KAPPA B; RENILLA; STILBENES;

PHOTINUS PYRALIS; RENILLA;

EID: 84872384855     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20120043     Document Type: Article

References (27)

1. de Wet, J. R., Wood, K. V., Helinski, D. R. and DeLuca, M. (1985) Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 82, 7870-7873 (Pubitemid 16169458)
2. Navizet, I., Liu, Y. J., Ferre, N., Roca-Sanjuan, D. and Lindh, R. (2011) The chemistry of boluminescence: an analysis of chemical functionalities. ChemPhysChem 12, 3064-3076
3. Leitao, J. M. and Esteves da Silva, J. C. (2010) Firefly luciferase inhibition. J. Photochem. Photobiol. B 101, 1-8
4. Hosseinkhani, S. (2011) Molecular enigma of multicolor bioluminescence of firefly luciferase. Cell. Mol. Life Sci. 68, 1167-1182
5. Fraga, H., Fernandes, D., Fontes, R. and Esteves da Silva, J. C. (2005) Coenzyme A affects firefly luciferase luminescence because it acts as a substrate and not as an allosteric effector. FEBS J. 272, 5206-5216 (Pubitemid 41503151)
6. Auld, D. S., Southall, N. T., Jadhav, A., Johnson, R. L., Diller, D. J., Simeonov, A., Austin, C. P. and Inglese, J. (2008) Characterization of chemical libraries for luciferase inhibitory activity. J. Med. Chem. 51, 2372-2386 (Pubitemid 351628499)
7. Ribeiro, C. and Esteves da Silva, J. C. (2008) Kinetics of inhibition of firefly luciferase by oxyluciferin and dehydroluciferyl-adenylate. Photochem. Photobiol. Sci. 7, 1085-1090
8. Filippova, N. and Ugarova, N. N. (1982) Inhibition of luciferase from the firefly Luciola mingrelica by ATP analogs. Biokhimiia 47, 1342-1348
9. Franks, N. P., Jenkins, A., Conti, E., Lieb, W. R. and Brick, P. (1998) Structural basis for the inhibition of firefly luciferase by a general anesthetic. Biophys. J. 75, 2205-2211 (Pubitemid 28492103)
10. Ebrahimi, M., Hosseinkhani, S., Heydari, A., Khavari-Nejad, R. A. and Akbari, J. (2012) Controversial effect of two methylguanidine-based ionic liquids on firefly luciferase. Photochem. Photobiol. Sci. 11, 828-834
11. Rocha, S., Campbell, K. J., Roche, K. C. and Perkins, N. D. (2003) The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro. BMC Mol. Biol. 4, 9
12. Bakhtiarova, A., Taslimi, P., Elliman, S. J., Kosinski, P. A., Hubbard, B., Kavana, M. and Kemp, D. M. (2006) Resveratrol inhibits firefly luciferase. Biochem. Biophys. Res. Commun. 351, 481-484 (Pubitemid 44666713)
13. Heynekamp, J. J., Weber, W. M., Hunsaker, L. A., Gonzales, A. M., Orlando, R. A., Deck, L. M. and Jagt, D. L. (2006) Substituted trans-stilbenes, including analogues of the natural product resveratrol, inhibit the human tumor necrosis factor α-induced activation of transcription factor nuclear factor κB. J. Med. Chem. 49, 7182-7189 (Pubitemid 44886003)
14. Nordeen, S. K. (1988) Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6, 454-458
15. Braeuning, A., Menzel, M., Kleinschnitz, E. M., Harada, N., Tamai, Y., Kohle, C., Buchmann, A. and Schwarz, M. (2007) Serum components and activated Ha-Ras antagonize expression of perivenous marker genes stimulated by β-catenin signaling in mouse hepatocytes. FEBS J. 274, 4766-4777 (Pubitemid 47353126)
16. Ring, L., Perobner, I., Karow, M., Jochum, M., Neth, P. and Faussner, A. (2011) Reporter gene HEK-293 cells and WNT/frizzled fusion proteins as tools to study WNT signaling pathways. Biol. Chem. 392, 1011-1020
17. Uibel, F., Muhleisen, A., Kohle, C., Weimer, M., Stummann, T. C., Bremer, S. and Schwarz, M. (2010) ReProGlo: a new stem cell-based reporter assay aimed to predict embryotoxic potential of drugs and chemicals. Reprod. Toxicol. 30, 103-112
18. Gaunitz, F. and Papke, M. (1998) Gene transfer and expression. Methods Mol. Biol. 107, 361-370
19. Dyer, B. W., Ferrer, F. A., Klinedinst, D. K. and Rodriguez, R. (2000) A noncommercial dual luciferase enzyme assay system for reporter gene analysis. Anal. Biochem. 282, 158-161 (Pubitemid 30409441)
20. Craig, F. F., Simmonds, A. C., Watmore, D., McCapra, F. and White, M. R. (1991) Membrane-permeable luciferin esters for assay of firefly luciferase in live intact cells. Biochem. J. 276, 637-641
21. Braeuning, A. and Schwarz, M. (2010) Zonation of heme synthesis enzymes in mouse liver and their regulation by β-catenin and Ha-ras. Biol. Chem. 391, 1305-1313
22. Pfaffl, M. W. (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29, e45
23. Walle, T., Hsieh, F., DeLegge, M. H., Oatis, Jr, J. E. and Walle, U. K. (2004) High absorption but very low bioavailability of oral resveratrol in humans. Drug Metab. Dispos. 32, 1377-1382 (Pubitemid 39564557)
24. Yu, C., Shin, Y. G., Chow, A., Li, Y., Kosmeder, J. W., Lee, Y. S., Hirschelman, W. H., Pezzuto, J. M., Mehta, R. G. and van Breemen, R. B. (2002) Human, rat, and mouse metabolism of resveratrol. Pharm. Res. 19, 1907-1914 (Pubitemid 36016041)
25. Ugarova, N. N. (1989) Luciferase of Luciola mingrelica fireflies. Kinetics and regulation mechanism. J. Biolumin. Chemilumin. 4, 406-418
26. Varney, M. A., Cosford, N. D., Jachec, C., Rao, S. P., Sacaan, A., Lin, F. F., Bleicher, L., Santori, E. M., Flor, P. J., Allgeier, H. et al. (1999) SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5. J. Pharmacol. Exp. Ther. 290, 170-181 (Pubitemid 29302317)
27. Auld, D. S., Zhang, Y. Q., Southall, N. T., Rai, G., Landsman, M., MacLure, J., Langevin, D., Thomas, C. J., Austin, C. P. and Inglese, J. (2009) A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. J. Med. Chem. 52, 1450-1458