CD44+/CD24- breast cancer cells isolated from MCF-7 cultures exhibit enhanced angiogenic properties

Clinical and Translational Oncology

Volumn 15, Issue 1, 2013, Pages 46-54

  Sun, Hongmei ^a   Jia, Jun ^a   Wang, Xiaoli ^a   Ma, Bo ^a   Di, Lijun ^a   Song, Guohong ^a   Ren, Jun ^a,b  

^a PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Angiogenesis; Breast cancer; Stem cells

Indexed keywords

ANGIOTENSIN I; ANGIOTENSIN II; BEVACIZUMAB; CD24 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; HERMES ANTIGEN; INTERLEUKIN 8; PLATELET DERIVED GROWTH FACTOR B; VASCULOTROPIN A; VASCULOTROPIN B;

ANALYSIS OF VARIANCE; ARTICLE; BREAST CANCER; CANCER CELL; CARCINOGENESIS; CELL FUNCTION; CELL MIGRATION; CHORIOALLANTOIS; CONTROLLED STUDY; ENZYME ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PHENOTYPE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIGENS, CD24; ANTIGENS, CD44; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; DRUG RESISTANCE, NEOPLASM; ENDOTHELIAL CELLS; FEMALE; HUMANS; NEOPLASTIC STEM CELLS; NEOVASCULARIZATION, PATHOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84872380214     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/s12094-012-0891-2     Document Type: Article

References (41)

1. Calabrese C, Poppleton H, Kocak M et al (2007) A perivascular niche for brain tumor stem cells. Cancer Cell 11(1):69-82
2. Beck B, Driessens G, Goossens S et al (2011) A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours. Nature 478(7369):399-403
3. Shen R, Ye Y, Chen L et al (2008) Precancerous stem cells can serve as tumor vasculogenic progenitors. PloS One 3(2):e1652
4. Wang R, Chadalavada K, Wilshire J et al (2010) Glioblastoma stem-like cells give rise to tumour endothelium. Nature 468(7325):829-833
5. Sneddon JB, Werb Z (2007) Location, location, location: the cancer stem cell niche. Cell Stem Cell 1(6):607-611
6. Bao S, Wu Q, Sathornsumetee S et al (2006) Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res 66(16):7843-7848
7. Al-Hajj M, Wicha MS, Benito-Hernandez A et al (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100(7):3983-3988
8. - /low/ABCG2-cells and poor prognosis in breast cancer. Beijing Da Xue Xue Bao 40(5):465-470
9. - /low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis. Clin Cancer Res 11(3):1154-1159
10. Liu R, Wang X, Chen GY et al (2007) The prognostic role of a gene signature from tumorigenic breast-cancer cells. New Engl J Med 356(3):217-226
11. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25(4):402-408
12. Dean M, Fojo T, Bates S (2005) Tumour stem cells and drug resistance. Nature Rev 5(4):275-284
13. Okabe M, Tsukahara Y, Tanaka M et al (2009) Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver. Development 136(11):1951-1960
14. Ginestier C, Hur MH, Charafe-Jauffret E et al (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1(5):555-567
15. Croker AK, Goodale D, Chu J et al (2009) High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability. J Cell Mol Med 13(8B):2236-2252
16. Charafe-Jauffret E, Ginestier C, Monville F et al (2006) Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene 25(15):2273-2284
17. Sorlie T, Perou CM, Tibshirani R et al (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98(19):10869-10874
18. Ailles LE, Weissman IL (2007) Cancer stem cells in solid tumors. Curr Opin Biotechnol 18(5):460-466
19. Ponti D, Costa A, Zaffaroni N et al (2005) Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 65(13):5506-5511
20. Zhang Y, Toy KA, Kleer CG (2012) Metaplastic breast carcinomas are enriched in markers of tumor-initiating cells and epithelial to mesenchymal transition. Mod Pathol 25(2):178-184
21. Ratajczak M, Tarnowski M, Staniszewska M et al (2010) Mechanisms of cancer metastasis: involvement of cancer stem cells? Minerva Med 101(3):179-191
22. Arima Y, Hayashi N, Hayashi H et al (2012) Loss of p16 expression is associated with the stem cell characteristics of surface markers and therapeutic resistance in estrogen receptor-negative breast cancer. Int J Cancer 130(11):2568-2579
23. Idowu MO, Kmieciak M, Dumur C et al (2012) CD44(+)/CD24(-/low) cancer stem/progenitor cells are more abundant in triple-negative invasive breast carcinoma phenotype and are associated with poor outcome. Hum Pathol 43(3):364-373
24. Sheridan C, Kishimoto H, Fuchs RK et al (2006) CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res 8(5):R59
25. Saarinen NM, Abrahamsson A, Dabrosin C (2010) Estrogen-induced angiogenic factors derived from stromal and cancer cells are differently regulated by enterolactone and genistein in human breast cancer in vivo. Int J Cancer 127(3):737-745
26. Joyce JA, Pollard JW (2009) Microenvironmental regulation of metastasis. Nat Rev 9(4):239-252
27. Ambasta RK, Sharma A, Kumar P (2011) Nanoparticle mediated targeting of VEGFR and cancer stem cells for cancer therapy. Vasc Cell 3(1):26
28. Liekens S, Schols D, Hatse S (2011) CXCL12-CXCR4 axis in angiogenesis, metastasis and stem cell mobilization. Curr Pharm Des 16(35):3903-3920
29. Ehtesham M, Mapara KY, Stevenson CB et al (2009) CXCR4 mediates the proliferation of glioblastoma progenitor cells. Cancer Lett 274(2):305-312
30. Sakariassen PO, Prestegarden L, Wang J et al (2006) Angiogenesis- independent tumor growth mediated by stem-like cancer cells. Proc Natl Acad Sci USA 103(44):16466-16471
31. Jeyapalan Z, Deng Z, Shatseva T et al (2011) Expression of CD44 3′-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis. Nucleic Acids Res 39(8):3026-3041
32. Bretz N, Noske A, Keller S et al (2011) CD24 promotes tumor cell invasion by suppressing tissue factor pathway inhibitor-2 (TFPI-2) in a c-Src-dependent fashion. Clin Exp Metastasis 29(1):27-38
33. Schabath H, Runz S, Joumaa S et al (2006) CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells. J Cell Sci 119(Pt 2):314-325
34. Kerbel RS (2008) Tumor angiogenesis. New Engl J Med 358(19):2039-2049
35. Kim KJ, Li B, Winer J et al (1993) Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362(6423):841-844
36. Relf M, LeJeune S, Scott PA et al (1997) Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res 57(5):963-969
37. Hanrahan V, Currie MJ, Gunningham SP et al (2003) The angiogenic switch for vascular endothelial growth factor (VEGF)-A, VEGF-B, VEGF-C, and VEGF-D in the adenoma-carcinoma sequence during colorectal cancer progression. J Pathol 200(2):183-194
38. Viacava P, Naccarato AG, Bocci G et al (2004) Angiogenesis and VEGF expression in pre-invasive lesions of the human breast. J Pathol 204(2):140-146
39. Bergers G, Javaherian K, Lo KM et al (1999) Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science 284(5415):808-812
40. Hamilton EP, Blackwell KL (2011) Safety of bevacizumab in patients with metastatic breast cancer. Oncology 80(5-6):314-325
41. Besancon R, Valsesia-Wittmann S, Puisieux A et al (2009) Cancer stem cells: the emerging challenge of drug targeting. Curr Med Chem 16(4):394-416