메뉴 건너뛰기




Volumn 430, Issue 2, 2013, Pages 653-658

P21WAF1/CIP1 deficiency induces mitochondrial dysfunction in HCT116 colon cancer cells

Author keywords

AMPK; Mitochondria; P21; PGC 1

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; GALACTOSE; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; AMP ACTIVATED PROTEIN KINASE KINASE; AMP-ACTIVATED PROTEIN KINASE KINASE; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PROTEIN KINASE; TUMOR SUPPRESSOR PROTEIN;

EID: 84872347549     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.11.096     Document Type: Article
Times cited : (14)

References (30)
  • 1
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper J.W., Adami G.R., Wei N., Keyomarsi K., Elledge S.J. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993, 75:805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 2
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan D.O. Principles of CDK regulation. Nature 1995, 374:131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 3
    • 77951978240 scopus 로고    scopus 로고
    • Multiple roles of the cell cycle inhibitor p21(CDKN1A) in the DNA damage response
    • Cazzalini O., Scovassi A.I., Savio M., Stivala L.A., Prosperi E. Multiple roles of the cell cycle inhibitor p21(CDKN1A) in the DNA damage response. Mutat. Res. 2010, 704:12-20.
    • (2010) Mutat. Res. , vol.704 , pp. 12-20
    • Cazzalini, O.1    Scovassi, A.I.2    Savio, M.3    Stivala, L.A.4    Prosperi, E.5
  • 4
    • 67649424560 scopus 로고    scopus 로고
    • P21 in cancer: intricate networks and multiple activities
    • Abbas T., Dutta A. p21 in cancer: intricate networks and multiple activities. Nat. Rev. Cancer 2009, 9:400-414.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 5
    • 0035821788 scopus 로고    scopus 로고
    • P21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents
    • Mahyar-Roemer M., Roemer K. p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. Oncogene 2001, 20:3387-3398.
    • (2001) Oncogene , vol.20 , pp. 3387-3398
    • Mahyar-Roemer, M.1    Roemer, K.2
  • 6
    • 0037042177 scopus 로고    scopus 로고
    • Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts
    • Roninson I.B. Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts. Cancer Lett. 2002, 179:1-14.
    • (2002) Cancer Lett. , vol.179 , pp. 1-14
    • Roninson, I.B.1
  • 7
    • 24744454815 scopus 로고    scopus 로고
    • The conflicting roles of the cdk inhibitor p21(CIP1/WAF1) in apoptosis
    • Gartel A.L. The conflicting roles of the cdk inhibitor p21(CIP1/WAF1) in apoptosis. Leuk. Res. 2005, 29:1237-1238.
    • (2005) Leuk. Res. , vol.29 , pp. 1237-1238
    • Gartel, A.L.1
  • 11
    • 0033529790 scopus 로고    scopus 로고
    • P21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential
    • Topley G.I., Okuyama R., Gonzales J.G., Conti C., Dotto G.P. P21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential. Proc. Natl. Acad. Sci. USA 1999, 96:9089-9094.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9089-9094
    • Topley, G.I.1    Okuyama, R.2    Gonzales, J.G.3    Conti, C.4    Dotto, G.P.5
  • 12
    • 17744393686 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human disease
    • Taylor R.W., Turnbull D.M. Mitochondrial DNA mutations in human disease. Nat. Rev. Genet. 2005, 6:389-402.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 389-402
    • Taylor, R.W.1    Turnbull, D.M.2
  • 14
    • 14644422657 scopus 로고    scopus 로고
    • Alterations of mitochondrial DNA in common diseases and disease states: aging, neurodegeneration, heart failure, diabetes, and cancer
    • Kang D., Hamasaki N. Alterations of mitochondrial DNA in common diseases and disease states: aging, neurodegeneration, heart failure, diabetes, and cancer. Curr. Med. Chem. 2005, 12:429-441.
    • (2005) Curr. Med. Chem. , vol.12 , pp. 429-441
    • Kang, D.1    Hamasaki, N.2
  • 15
    • 84862811748 scopus 로고    scopus 로고
    • Loss of Med1/TRAP220 promotes the invasion and metastasis of human non-small-cell lung cancer cells by modulating the expression of metastasis-related genes
    • Kim H.J., Roh M.S., Son C.H., Kim A.J., Jee H.J., Song N., Kim M., Seo S.Y., Yoo Y.H., Yun J. Loss of Med1/TRAP220 promotes the invasion and metastasis of human non-small-cell lung cancer cells by modulating the expression of metastasis-related genes. Cancer Lett. 2012, 321:195-202.
    • (2012) Cancer Lett. , vol.321 , pp. 195-202
    • Kim, H.J.1    Roh, M.S.2    Son, C.H.3    Kim, A.J.4    Jee, H.J.5    Song, N.6    Kim, M.7    Seo, S.Y.8    Yoo, Y.H.9    Yun, J.10
  • 16
    • 34247640762 scopus 로고    scopus 로고
    • Identification of novel substrates for human checkpoint kinase Chk1 and Chk2 through genome-wide screening using a consensus Chk phosphorylation motif
    • Kim M.A., Kim H.J., Brown A.L., Lee M.Y., Bae Y.S., Park J.I., Kwak J.Y., Chung J.H., Yun J. Identification of novel substrates for human checkpoint kinase Chk1 and Chk2 through genome-wide screening using a consensus Chk phosphorylation motif. Exp. Mol. Med. 2007, 39:205-212.
    • (2007) Exp. Mol. Med. , vol.39 , pp. 205-212
    • Kim, M.A.1    Kim, H.J.2    Brown, A.L.3    Lee, M.Y.4    Bae, Y.S.5    Park, J.I.6    Kwak, J.Y.7    Chung, J.H.8    Yun, J.9
  • 17
    • 0024447105 scopus 로고
    • 10-N nonyl-acridine orange: a fluorescent probe which stains mitochondria independently of their energetic state
    • Maftah A., Petit J.M., Ratinaud M.H., Julien R. 10-N nonyl-acridine orange: a fluorescent probe which stains mitochondria independently of their energetic state. Biochem. Biophys. Res. Commun. 1989, 164:185-190.
    • (1989) Biochem. Biophys. Res. Commun. , vol.164 , pp. 185-190
    • Maftah, A.1    Petit, J.M.2    Ratinaud, M.H.3    Julien, R.4
  • 18
    • 1542373685 scopus 로고    scopus 로고
    • Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
    • Kelly D.P., Scarpulla R.C. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev. 2004, 18:357-368.
    • (2004) Genes Dev. , vol.18 , pp. 357-368
    • Kelly, D.P.1    Scarpulla, R.C.2
  • 20
    • 0037058977 scopus 로고    scopus 로고
    • AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
    • Zong H., Ren J.M., Young L.H., Pypaert M., Mu J., Birnbaum M.J., Shulman G.I. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. Proc. Natl. Acad. Sci. USA 2002, 99:15983-15987.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 15983-15987
    • Zong, H.1    Ren, J.M.2    Young, L.H.3    Pypaert, M.4    Mu, J.5    Birnbaum, M.J.6    Shulman, G.I.7
  • 23
    • 83455205885 scopus 로고    scopus 로고
    • Galactose enhances oxidative metabolism and reveals mitochondrial dysfunction in human primary muscle cells
    • Aguer C., Gambarotta D., Mailloux R.J., Moffat C., Dent R., McPherson R., Harper M.E. Galactose enhances oxidative metabolism and reveals mitochondrial dysfunction in human primary muscle cells. PLoS ONE 2011, 6:e28536.
    • (2011) PLoS ONE , vol.6
    • Aguer, C.1    Gambarotta, D.2    Mailloux, R.J.3    Moffat, C.4    Dent, R.5    McPherson, R.6    Harper, M.E.7
  • 24
    • 34447577912 scopus 로고    scopus 로고
    • Circumventing the crabtree effect: replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants
    • Marroquin L.D., Hynes J., Dykens J.A., Jamieson J.D., Will Y. Circumventing the crabtree effect: replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants. Toxicol. Sci. 2007, 97:539-547.
    • (2007) Toxicol. Sci. , vol.97 , pp. 539-547
    • Marroquin, L.D.1    Hynes, J.2    Dykens, J.A.3    Jamieson, J.D.4    Will, Y.5
  • 25
    • 0033598444 scopus 로고    scopus 로고
    • Control of E2F activity by p21Waf1/Cip1
    • Delavaine L., La Thangue N.B. Control of E2F activity by p21Waf1/Cip1. Oncogene 1999, 18:5381-5392.
    • (1999) Oncogene , vol.18 , pp. 5381-5392
    • Delavaine, L.1    La Thangue, N.B.2
  • 26
    • 0034705540 scopus 로고    scopus 로고
    • Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1
    • Coqueret O., Gascan H. Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1. J. Biol. Chem. 2000, 275:18794-18800.
    • (2000) J. Biol. Chem. , vol.275 , pp. 18794-18800
    • Coqueret, O.1    Gascan, H.2
  • 27
    • 14844365000 scopus 로고    scopus 로고
    • P21WAF1/CIP1 selectively controls the transcriptional activity of estrogen receptor alpha
    • Fritah A., Saucier C., Mester J., Redeuilh G., Sabbah M. P21WAF1/CIP1 selectively controls the transcriptional activity of estrogen receptor alpha. Mol. Cell. Biol. 2005, 25:2419-2430.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 2419-2430
    • Fritah, A.1    Saucier, C.2    Mester, J.3    Redeuilh, G.4    Sabbah, M.5
  • 28
    • 0037158891 scopus 로고    scopus 로고
    • Transcriptional activation by the oestrogen receptor alpha is modulated through inhibition of cyclin-dependent kinases
    • Redeuilh G., Attia A., Mester J., Sabbah M. Transcriptional activation by the oestrogen receptor alpha is modulated through inhibition of cyclin-dependent kinases. Oncogene 2002, 21:5773-5782.
    • (2002) Oncogene , vol.21 , pp. 5773-5782
    • Redeuilh, G.1    Attia, A.2    Mester, J.3    Sabbah, M.4
  • 29
    • 22344436360 scopus 로고    scopus 로고
    • P21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
    • Devgan V., Mammucari C., Millar S.E., Brisken C., Dotto G.P. P21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes. Dev. 2005, 19:1485-1495.
    • (2005) Genes. Dev. , vol.19 , pp. 1485-1495
    • Devgan, V.1    Mammucari, C.2    Millar, S.E.3    Brisken, C.4    Dotto, G.P.5
  • 30
    • 84862630341 scopus 로고    scopus 로고
    • A new role for ATM: regulating mitochondrial function and mitophagy
    • Valentin-Vega Y.A., Kastan M.B. A new role for ATM: regulating mitochondrial function and mitophagy. Autophagy 2012, 8:840-841.
    • (2012) Autophagy , vol.8 , pp. 840-841
    • Valentin-Vega, Y.A.1    Kastan, M.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.