Effect of denosumab on bone mineral density and biochemical markers of bone turnover: 8-year results of a phase 2 clinical trial

Osteoporosis International

Volumn 24, Issue 1, 2013, Pages 227-235

  McClung, M R ^a   Lewiecki, E M ^b   Geller, M L ^c   Bolognese, M A ^d   Peacock, M ^e   Weinstein, R L ^f   Ding, B ^c   Rockabrand, E ^c   Wagman, R B ^c   Miller, P D ^g  

^a OREGON OSTEOPOROSIS CENTER   (United States)

^b NEW MEXICO CLINICAL RESEARCH AND OSTEOPOROSIS CENTER   (United States)

^c AMGEN INC   (United States)

^d Bethesda Health Research Center   (United States)

^e INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f Diablo Clinical Research   (United States)

^g University of Colorado Health Sciences Center   (United States)

Author keywords

Bone mineral density; Bone turnover markers; Denosumab; Osteoporosis; RANK ligand

Indexed keywords

ALENDRONIC ACID; ALKALINE PHOSPHATASE; BIOLOGICAL MARKER; COLLAGEN TYPE 1; DENOSUMAB; PLACEBO; TELOPEPTIDE;

ABNORMAL LABORATORY RESULT; ARTHRALGIA; ARTICLE; BACKACHE; BONE DENSITY; BONE TURNOVER; CATARACT; CONTACT DERMATITIS; DIVERTICULITIS; DRUG EFFECT; DRUG FATALITY; ECZEMA; ENDOCARDITIS; FRAGILITY FRACTURE; HIP; HUMAN; HYPERTENSION; LEG PAIN; LUMBAR SPINE; MULTICENTER STUDY; NEOPLASM; OSTEOPOROSIS; PHASE 2 CLINICAL TRIAL; PNEUMONIA; POSTMENOPAUSE; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; SINUSITIS; TREATMENT DURATION; URIANRY TRACT INFECTION;

AGED; ALKALINE PHOSPHATASE; ANTIBODIES, MONOCLONAL, HUMANIZED; BIOLOGICAL MARKERS; BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; BONE REMODELING; COLLAGEN TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HIP JOINT; HUMANS; LUMBAR VERTEBRAE; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; PEPTIDES; TREATMENT OUTCOME;

EID: 84872332488     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-012-2052-4     Document Type: Article

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