Susceptibility to cytotoxic T cell lysis of cancer stem cells derived from cervical and head and neck tumor cell lines

Journal of Cancer Research and Clinical Oncology

Volumn 139, Issue 1, 2013, Pages 159-170

  Liao, Tian ^a   Kaufmann, Andreas M ^a   Qian, Xu ^a   Sangvatanakul, Voramon ^a   Chen, Chao ^a   Kube, Tina ^a   Zhang, Guoyou ^b   Albers, Andreas E ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Aldehydehydrogenase; Cancer stem cell; Cervical carcinoma; Co stimulatory molecules; Cytotoxic T cell; Squamous cell cancer of the head and neck

Indexed keywords

ALLOANTIGEN; CELL MARKER; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN ALDH; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ANTIGEN SPECIFICITY; ARTICLE; CANCER CELL CULTURE; CANCER IMMUNOTHERAPY; CANCER STEM CELL; CANCER SUSCEPTIBILITY; CD8+ T LYMPHOCYTE; CELL KILLING; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; HEAD AND NECK TUMOR; HUMAN; HUMAN CELL; IMMUNOGENICITY; IN VITRO STUDY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; SPHEROID CELL; TUMOR CELL DESTRUCTION; TUMOR CELL LINE; TUMOR IMMUNITY; UPREGULATION; UTERINE CERVIX CANCER;

ANTIGENS, CD80; CARCINOMA, SQUAMOUS CELL; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MHC CLASS I; GENES, MHC CLASS II; HEAD AND NECK NEOPLASMS; HOMEODOMAIN PROTEINS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON-GAMMA; ISOENZYMES; MALE; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; RETINAL DEHYDROGENASE; SOXB1 TRANSCRIPTION FACTORS; SPHEROIDS, CELLULAR; T-LYMPHOCYTES, CYTOTOXIC; UTERINE CERVICAL NEOPLASMS;

EID: 84872320399     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-012-1311-2     Document Type: Article

References (33)

1. Albers A, Abe K, Hunt J, Wang J, Lopez-Albaitero A, Schaefer C, Gooding W, Whiteside TL, Ferrone S, DeLeo A, Ferris RL (2005) Antitumor activity of human papillomavirus type 16 E7-specific T cells against virally infected squamous cell carcinoma of the head and neck. Cancer Res 65(23):11146-11155. doi: 10.1158/0008-5472.CAN-05-0772
2. Albers AE, Strauss L, Liao T, Hoffmann TK, Kaufmann AM (2011) T cell-tumor interaction directs the development of immunotherapies in head and neck cancer. Clin Dev Immunol 2010:236378. doi: 10.1155/2010/236378
3. Andratschke M, Pauli C, Stein M, Chaubal S, Wollenberg B (2003) MHC-class I antigen expression on micrometastases in bone marrow of patients with head and neck squamous cell cancer. Anticancer Res 23(2B):1467-1471
4. Bortolomai I, Canevari S, Facetti I, De Cecco L, Castellano G, Zacchetti A, Alison MR, Miotti S (2010) Tumor initiating cells: development and critical characterization of a model derived from the A431 carcinoma cell line forming spheres in suspension. Cell Cycle 9(6):1194-1206
5. Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, Young RA (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122(6):947-956. doi: 10.1016/j.cell.2005.08.020
6. Brown CE, Starr R, Martinez C, Aguilar B, D'Apuzzo M, Todorov I, Shih CC, Badie B, Hudecek M, Riddell SR, Jensen MC (2009) Recognition and killing of brain tumor stem-like initiating cells by CD8 + cytolytic T cells. Cancer Res 69(23):8886-8893. doi: 10.1158/0008-5472.CAN-09-2687
7. Castriconi R, Daga A, Dondero A, Zona G, Poliani PL, Melotti A, Griffero F, Marubbi D, Spaziante R, Bellora F, Moretta L, Moretta A, Corte G, Bottino C (2009) NK cells recognize and kill human glioblastoma cells with stem cell-like properties. J Immunol 182(6):3530-3539. doi: 10.4049/jimmunol.0802845
8. Chen YC, Chen YW, Hsu HS, Tseng LM, Huang PI, Lu KH, Chen DT, Tai LK, Yung MC, Chang SC, Ku HH, Chiou SH, Lo WL (2009) Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer. Biochem Biophys Res Commun 385(3):307-313. doi: 10.1016/j.bbrc.2009.05.048
9. Chen C, Wei Y, Hummel M, Hoffmann TK, Gross M, Kaufmann AM, Albers AE (2011) Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma. PLoS ONE 6(1):e16466. doi: 10.1371/journal.pone.0016466
10. Clay MR, Tabor M, Owen JH, Carey TE, Bradford CR, Wolf GT, Wicha MS, Prince ME (2010) Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase. Head Neck 32(9):1195-1201. doi: 10.1002/hed.21315
11. Evans M, Borysiewicz LK, Evans AS, Rowe M, Jones M, Gileadi U, Cerundolo V, Man S (2001) Antigen processing defects in cervical carcinomas limit the presentation of a CTL epitope from human papillomavirus 16 E6. J Immunol 167(9):5420-5428
12. Garcia-Hernandez Mde L, Gray A, Hubby B, Klinger OJ, Kast WM (2008) Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity. Cancer Res 68(3):861-869. doi: 10.1158/0008-5472.CAN-07-0445
13. Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M, Jacquemier J, Viens P, Kleer CG, Liu S, Schott A, Hayes D, Birnbaum D, Wicha MS, Dontu G (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1(5):555-567. doi: 10.1016/j.stem.2007.08.014
14. Hoffmann TK, Sonkoly E, Hauser U, van Lierop A, Whiteside TL, Klussmann JP, Hafner D, Schuler P, Friebe-Hoffmann U, Scheckenbach K, Erjala K, Grenman R, Schipper J, Bier H, Balz V (2008) Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma. Oral Oncol 44(12):1100-1109. doi: 10.1016/j.oraloncology.2008.02.006
15. Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, Fields JZ, Wicha MS, Boman BM (2009) Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res 69(8):3382-3389. doi: 10.1158/0008-5472.CAN-08- 4418
16. Jiang F, Qiu Q, Khanna A, Todd NW, Deepak J, Xing L, Wang H, Liu Z, Su Y, Stass SA, Katz RL (2009) Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer. Mol Cancer Res 7(3):330-338. doi: 10.1158/1541-7786.MCR-08-0393
17. Loh YH, Wu Q, Chew JL, Vega VB, Zhang W, Chen X, Bourque G, George J, Leong B, Liu J, Wong KY, Sung KW, Lee CW, Zhao XD, Chiu KP, Lipovich L, Kuznetsov VA, Robson P, Stanton LW, Wei CL, Ruan Y, Lim B, Ng HH (2006) The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 38(4):431-440. doi: 10.1038/ng1760
18. Ma S, Chan KW, Lee TK, Tang KH, Wo JY, Zheng BJ, Guan XY (2008) Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations. Mol Cancer Res 6(7):1146-1153. doi: 10.1158/1541-7786.MCR-08-0035
19. Mehta AM, Jordanova ES, Kenter GG, Ferrone S, Fleuren GJ (2008) Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma. Cancer Immunol Immunother 57(2):197-206. doi: 10.1007/s00262-007-0362-8
20. Meissner M, Reichert TE, Kunkel M, Gooding W, Whiteside TL, Ferrone S, Seliger B (2005) Defects in the human leukocyte antigen class I antigen processing machinery in head and neck squamous cell carcinoma: association with clinical outcome. Clin Cancer Res 11(7):2552-2560. doi: 10.1158/1078-0432.CCR- 04-2146
21. Okamoto A, Chikamatsu K, Sakakura K, Hatsushika K, Takahashi G, Masuyama K (2009) Expansion and characterization of cancer stem-like cells in squamous cell carcinoma of the head and neck. Oral Oncol 45(7):633-639. doi: 10.1016/j.oraloncology.2008.10.003
22. Pellegatta S, Poliani PL, Corno D, Menghi F, Ghielmetti F, Suarez-Merino B, Caldera V, Nava S, Ravanini M, Facchetti F, Bruzzone MG, Finocchiaro G (2006) Neurospheres enriched in cancer stem-like cells are highly effective in eliciting a dendritic cell-mediated immune response against malignant gliomas. Cancer Res 66(21):10247-10252. doi: 10.1158/0008-5472.CAN-06-2048
23. Prasmickaite L, Engesaeter BO, Skrbo N, Hellenes T, Kristian A, Oliver NK, Suo Z, Maelandsmo GM (2010) Aldehyde dehydrogenase (ALDH) activity does not select for cells with enhanced aggressive properties in malignant melanoma. PLoS ONE 5(5):e10731. doi: 10.1371/journal.pone.0010731
24. Stanke J, Hoffmann C, Erben U, von Keyserling H, Stevanovic S, Cichon G, Schneider A, Kaufmann AM (2010) A flow cytometry-based assay to assess minute frequencies of CD8 + T cells by their cytolytic function. J Immunol Methods 360(1-2):56-65. doi: 10.1016/j.jim.2010.06.005
25. Street D, Kaufmann AM, Vaughan A, Fisher SG, Hunter M, Schreckenberger C, Potkul RK, Gissmann L, Qiao L (1997) Interferon-gamma enhances susceptibility of cervical cancer cells to lysis by tumor-specific cytotoxic T cells. Gynecol Oncol 65(2):265-272. doi: 10.1006/gyno.1997.4667
26. Todaro M, Lombardo Y, Stassi G (2010) Evidences of cervical cancer stem cells derived from established cell lines. Cell Cycle 9(7):1238-1239
27. Visus C, Ito D, Amoscato A, Maciejewska-Franczak M, Abdelsalem A, Dhir R, Shin DM, Donnenberg VS, Whiteside TL, DeLeo AB (2007) Identification of human aldehyde dehydrogenase 1 family member A1 as a novel CD8 + T-cell-defined tumor antigen in squamous cell carcinoma of the head and neck. Cancer Res 67(21):10538-10545. doi: 10.1158/0008-5472.CAN-07-1346
28. Visus C, Wang Y, Lozano-Leon A, Ferris RL, Silver S, Szczepanski MJ, Brand RE, Ferrone CR, Whiteside TL, Ferrone S, DeLeo AB, Wang X (2011) Targeting ALDH(bright) human carcinoma-initiating cells with ALDH1A1-specific CD8(+) T cells. Clin Cancer Res 17(19):6174-6184. doi: 10.1158/1078-0432.CCR-11-1111
29. Visvader JE, Lindeman GJ (2008) Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8(10):755-768. doi: 10.1038/nrc2499
30. Wollenberg B, Zeidler R, Lebeau A, Mack B, Lang S (1998) Lack of B7.1 and B7.2 on head and neck cancer cells and possible significance for gene therapy. Int J Mol Med 2(2):167-171
31. Wu A, Wiesner S, Xiao J, Ericson K, Chen W, Hall WA, Low WC, Ohlfest JR (2007) Expression of MHC I and NK ligands on human CD133 + glioma cells: possible targets of immunotherapy. J Neurooncol 83(2):121-131. doi: 10.1007/s11060-006-9265-3
32. Xu Q, Liu G, Yuan X, Xu M, Wang H, Ji J, Konda B, Black KL, Yu JS (2009) Antigen-specific T-cell response from dendritic cell vaccination using cancer stem-like cell-associated antigens. Stem Cells 27(8):1734-1740. doi: 10.1002/stem.102
33. Yoshida A (1992) Molecular genetics of human aldehyde dehydrogenase. Pharmacogenetics 2(4):139-147