A novel method for simultaneous monitoring of 2-MCPD, 3-MCPD and glycidyl esters in oils and fats

JAOCS, Journal of the American Oil Chemists' Society

Volumn 90, Issue 1, 2013, Pages 1-8

  Ermacora, A ^a   Hrncirik, K ^a  

^a UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

Author keywords

2 MCPD esters; 3 MCPD esters; Acid transesterification; Analysis; Chloropropanols; Fats; Glycidol; Glycidyl esters; MBPD; Oils; Process contaminants

Indexed keywords

3-MCPD ESTERS; ANALYSIS; CHLOROPROPANOLS; GLYCIDOL; GLYCIDYL ESTERS; MBPD; OILS;

ESTERS; OILS AND FATS; OPTIMIZATION;

ESTERIFICATION;

EID: 84872314334     PISSN: 0003021X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11746-012-2132-9     Document Type: Article

References (22)

1. Velíšek J, Davídek J, Kubelka V, Janíček G, Svobodová Z, Šimicová Z (1980) New chlorine-containing organic compounds in protein hydrolysates. J Agric Food Chem 28:1142-1144
2. Svejkovská B, Novotný O, Divinová V, Réblová Z, Doležal M, Velíšek J (2004) Esters of 3-chloropropane-1,2-diol in foodstuffs. Czech J Food Sci 22:190-196 (Pubitemid 40008126)
3. European Commission, Scientific Committee on Food (2001) Opinion on 3-monochloro-propane-1,2-diol (3-MCPD); SCF/CS/CNTM/OTH/17 Final. Available from: http://ec.europa.eu/food/fs/sc/scf/out91-en.pdf
4. Kuhlmann J (2008) Überbefunde bei der Bestimmung von 3-MCPD-Estern in Ölen & Fetten? Mögliche Ursachen und Konsequenzen. Oral presentation. 2nd Workshop on analysis of 3-MCPD-esters in edible oils, Federal Institute for Risk Assesment (BfR), Berlin
5. Weißhaar R, Perz R (2010) Fatty acid esters of glycidol in refined fats and oils. Eur J Lipid Sci Technol 112:158-165
6. Habermeyer M, Guth S, Eisenbrand G (2011) Identification of gaps in knowledge concerning toxicology of 3-MCPD and glycidol esters. Eur J Lipid Sci Technol 113:314-318
7. Hrnčiřík K, van Duijn G (2011) An initial study on the formation of 3-MCPD esters during oil refining. Eur J Lipid Sci Technol 113:374-379
8. Divinová V, Svejkovská B, Doležal M, Velíšek J (2004) Determination of free and bound 3-chloropropane-1,2-diol by gas chromatography with mass spectrometric detection using deuterated 3-chloropropane-1,2-diol as internal standard. Czech J Food Sci 22:182-189 (Pubitemid 40008125)
9. Weißhaar R (2008) Determination of total 3-chloropropane-1,2-diol (3-MCPD) in edible oils by cleavage of MCPD esters with sodium methoxide. Eur J Lipid Sci Technol 110:183-186
10. Kuhlmann J (2011) Determination of bound 2,3-epoxy-1-propanol (glycidol) and bound monochloropropanediol (MCPD) in refined oils. Eur J Lipid Sci Technol 113:335-344
11. Karasek L, Wenzl T, Ulberth F (2010) Proficiency test on the determination of 3-MCPD esters in edible oil [Internet]. Geel (Belgium): Publications Office of the European Union. Available from: http://irmm.jrc.ec. europa.eu/html/interlaboratory-comparisons/3-MCPD/index.htm
12. Hrnčiřík K, Zelinková Z, Ermacora A (2011) Critical factors of indirect determination of 3-chloropropane-1,2-diol esters. Eur J Lipid Sci Technol 113:361-367
13. Federal Institute for Risk Assessment (2010) Second collaborative study for the determination of 3-mcpd-fatty acid esters in edible fats and oils, method validation and proficiency test, final report (unpublished)
14. Ermacora A, Hrnčiřík K (2011) 3-MCPD esters analysis: An optimized method based on acid transesterification. 7th AOCS expert panel on process contaminants. Oral presentation. Available from: http://www.aocs.org/files/ResourcesPDF/notes%207th%20expert%20panel.pdf
15. Masukawa Y, Shiro H, Nakamura S, Kondo N, Jin N, Suzuki N, Ooi N, Kudo N (2010) A new analytical method for the quantification of glycidol fatty acid esters in edible oils. J Oleo Sci 59:81-88
16. Haines TD, Adlaf KJ, Pierceall RM, Lee I, Venkitasubramanian P, Collison MW (2011) Direct determination of MCPD fatty acid esters and glycidyl fatty acid esters in vegetable oils by LC-TOFMS. J Am Oil Chem Soc 88:1-14
17. DGF. Deutsche Gesellschaft für Fettwissenschaft: DGF Standard Method C-VI 18 (2011) Fatty-acid-bound 3-chloropropane-1,2-diol (3-MCPD) and 2,3-epoxipropane-1-ol (glycidol). Determination in oils and fats by GC/MS (Differential measurement). Deutsche Einheitsmethoden zur Untersuchung von Fetten, Fettprodukten, Tensiden und verwandten Stoffen [Internet]. Stuttgart (Germany): Wissenschaftliche Verlagsgesellschaft. Available from: http://www.dgfett.de/methods/c-vi-18-%2810%29-english.pdf
18. Ermacora A, Hrnčiřík K (2012) Evaluation of an improved indirect method for the analysis of 3-MCPD esters based on acid transesterification. J Am Oil Chem Soc 89:211-217
19. Kraft R, Brachwitz H, Etzold G, Langen P, Zöpel H-J (1979) Massenspektrometrische Strukturuntersuchung stellungsisomerer Fettsäureester der Halogenpropandiole (Desoxyhalogen-glyceride). J Prakt Chem 321:756-768
20. Bruice PY (2007) Substitution reactions of alkyl halides. Organic Chemistry, 5th ed. Pearson International Inc., Upper Saddle river, NJ, pp 344-388
21. Parker RE, Isaacs NS (1959) Mechanism of epoxide reactions. Chem Rev 159:737-799
22. Brønsted JN, Kilpatrick M, Kilpatrick M (1929) Kinetic studies of ethylene oxides. J Am Chem Soc 51:428-461