Association of plasma retinol binding protein-4 (RBP4) and sonographic grading of fatty liver in obese Iranian children

Hepatitis Monthly

Volumn 12, Issue 12, 2012, Pages

  Saki, Forough ^a   Karamizadeh, Zohreh ^a   Honar, Naser ^a   Moravej, Hossein ^a   Ashkani Esfahani, Soheil ^a   Namvar Shooshtarian, Mohammad Hossein ^b  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Department of Pathology   (Iran)

Author keywords

Child; Fatty Liver; Obesity; RBP4 Protein, Human; Ultrasonography

Indexed keywords

PLASMA RETINOL BINDING PROTEIN; PLASMA RETINOL BINDING PROTEIN 4; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADOLESCENT; ARTICLE; BODY MASS; CASE CONTROL STUDY; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; ECHOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IRAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; OBESITY; PRESCHOOL CHILD; SCHOOL CHILD;

EID: 84872311785     PISSN: 1735143X     EISSN: 17353408     Source Type: Journal    
DOI: 10.5812/hepatmon.7103     Document Type: Article

References (18)

1. Aeberli I, Biebinger R, Lehmann R, Allemand D, Spinas G, Zimmermann MB. Serum retinol-binding protein 4 concentration and its ratio to serum retinol are associated with obesity and metabolic syndrome components in children. J Clin Endocin Met. 2007;92(11):4359-65.
2. Weis R, Caprio S. The metabolic consequence of childhood obesity. Best Pract Res Clin Endocrinol Metab. 2005;19(3):405-19.
3. Lebensztejn DM, Wojtkowska M, Skiba E, Werpachowska I, Tobolczyk J, Kaczmarski M. serum concentration of adioponectin, leptin and resistin in obese children with nonalcoholic fatty liver disease. Adv Med Sci. 2009;54:177-82.
4. Louthan MV, Barve S, McClain CJ, Joshi-Barve S. Decreased serum adiponectin: an early event in pediatric non alcoholic fatty liver disease. J Pediatr. 2005;147:835-8.
5. Christou GA, Tselepis AD, Kiortsis DN. The metabolic role of retinol binding protein 4: An update. Horm Metab Res. 2012;44:6-14.
6. Kotnik P, Fischer-Posovszky P, Wabitsch M. RBP4: a controversial adipokine. Eur J Endocrinol. 2011;165:703-11.
7. Joseph AE, Saverymuttu SH, al-Sam S, Cook MG, Maxwell JD. Comparison of liver histology with ultrasonography in assessing diffuse parenchymal liver disease. Clin Radiol. 1991;43:26-31.
8. Devadason CA, Scheimann AO. Overview of screening methods for fatty liver disease in children. World J Hepatol. 2012;27(4):1-4.
9. Saverymuttu SH, Joseph AE, Maxwell JD. Ultrasound scanning in detection of hepatic fibrosis and steatosis. Br Med J (Clin Res Ed). 1986;292:13-5.
10. Romanowska A, Lebensztejn DM, Skiba E, Tarasow E, Kaczmarski M. Retinol binding protein-4 as a serum biomarker of intrahepatic lipid content in obese children-preliminary report. Acta Biochim Pol. 2011;58(1):35-8.
11. Alkhouri N, Lopez R, Berk M, Feldstein A. serum retinol-Binding protein 4 (RBP4) levels in patients with nonalcoholic fatty liver disease. J Clin gastroenterol. 2009;43(10):985-9.
12. Seo JA, Kim NH, Park Sy, Kim HY, Ryu OH, Lee KW, et al. Serum retinol-binding protein 4 levels are elevated in non-alcoholic fatty liver disease. Clin Endocrinol (Oxf). 2008;68(4):555-60.
13. Wu H, Jia W, Bao Y, Lu J, Zhu J, wang R, et al. Serum retinol binding protein 4 and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus. Diabetes Res Clin Pract. 2008;79(2):185-90.
14. Balagopal P, Graham TE, Kahn BB, Altomare A, Funanage V, George D. Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention: association with subclinical inflammation. J Clin Endocrin Metab. 2007;92:1971-74.
15. Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature. 2005;436:356-62.
16. Kanaka-Gantenbein C, Margeli A, Pervanidou P, Sakka S, Mastorakos G, Chrousos GP, et al. Retinol-Binding Protein 4 and Lipocalin-2 in Childhood and Adolescent Obesity: When Children Are Not Just "Small Adults". Clinical Chemistry. 2008;54(7):1176-82.
17. Milner K-L, van der Poorten D, Bugianesi E, Kench JG, Lam KSL, Chisholm DJ, et al. Adipocyte fatty acid binding protein levels relate to inflammation and fibrosis in nonalcoholic fatty liver disease. Hepatology. 2009;49:1936-4.
18. Schina M, Koskinas J, Tiniakos D, Hadziyannis E, Savvas S, Karamanos B, et al. Circulating and liver tissue levels of retinol-binding protein-4 in non-alcoholic fatty liver disease. Hepatol Res. 2009;39:972-8.