Serum retinol-binding protein 4 levels in patients with nonalcoholic fatty liver disease

Journal of Clinical Gastroenterology

Volumn 43, Issue 10, 2009, Pages 985-989

  Alkhouri, Naim ^a   Lopez, Rocio ^b   Berk, Michael ^a   Feldstein, Ariel E ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b Department of Quantitative Health Sciences ^*

Author keywords

Diabetes; Insulin resistance; Nonalcoholic steatohepatitis; Retinol binding protein 4; Steatosis

Indexed keywords

RETINOL BINDING PROTEIN 4; PLASMA RETINOL BINDING PROTEIN; RBP4 PROTEIN, HUMAN;

ADULT; ARTICLE; BODY MASS; CLINICAL ARTICLE; COHORT ANALYSIS; DIABETES MELLITUS; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FATTY LIVER; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; LIVER BIOPSY; LIVER FIBROSIS; MALE; NONALCOHOLIC FATTY LIVER; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RATING SCALE; SERUM; LIVER CIRRHOSIS; METABOLISM; MIDDLE AGED; OBESITY; PATHOPHYSIOLOGY;

ADULT; BODY MASS INDEX; COHORT STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FATTY LIVER; FEMALE; HUMANS; INSULIN RESISTANCE; LIVER CIRRHOSIS; MALE; MIDDLE AGED; OBESITY; RETINOL-BINDING PROTEINS, PLASMA;

EID: 74949109369     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/MCG.0b013e3181a0998d     Document Type: Article

References (25)

1. Bloomgarden ZT. Second world congress on the insulin resistance syndrome: hypertension, cardiovascular disease, and treatment approaches. Diabetes Care. 2005;28:2073-2080.
2. Bugianesi E, McCullough AJ, Marchesini G. Insulin resistance: a metabolic pathway to chronic liver disease. Hepatology. 2005;42:987-1000.
3. Bacon BR, Farahvash MJ, Janney CG, et al. Nonalcoholic steatohepatitis: an expanded clinical entity. Gastroenterology. 1994;107:1103-1109.
4. Matteoni CA, Younossi ZM, Gramlich T, et al. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology. 1999;116:1413-1419.
5. McCullough AJ. Pathophysiology of nonalcoholic steatohepatitis. J Clin Gastroenterol. 2006;40(suppl 1):S17-S29.
6. Quadro L, Blaner WS, Salchow DJ, et al. Impaired retinal function and vitamin A availability in mice lacking retinolbinding protein. EMBO J. 1999;18:4633-4644.
7. Yang Q, Graham TE, Mody N, et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature. 2005;436:356-362.
8. Graham TE, Yang Q, Bluher M, et al. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N Engl J Med. 2006;354:2552-2563.
9. Janke J, Engeli S, Boschmann M, et al. Retinol-binding protein 4 in human obesity. Diabetes. 2006;55:2805-2810.
10. Lewis JG, Shand BI, Frampton CM, et al. An ELISA for plasma retinol-binding protein using monoclonal and polyclonal antibodies: plasma variation in normal and insulin resistant subjects. Clin Biochem. 2007;40:828-834.
11. Lewis JG, Shand BI, Frampton CM, et al. Plasma retinolbinding protein is not a marker of insulin resistance in overweight subjects: a three year longitudinal study. Clin Biochem. 2008;41:1034-1038.
12. Promintzer M, Krebs M, Todoric J, et al. Insulin resistance is unrelated to circulating retinol binding protein and protein C inhibitor. J Clin Endocrinol Metab. 2007;92:4306-4312.
13. Tsutsumi C, Okuno M, Tannous L, et al. Retinoids and retinoid-binding protein expression in rat adipocytes. J Biol Chem. 1992;267:1805-1810.
14. Petta S, Camma C, Di Marco V, et al. Retinol-binding protein 4: a new marker of virus-induced steatosis in patients infected with hepatitis c virus genotype 1. Hepatology (Baltimore, MD). 2008;48:28-37.
15. Seo JA, Kim NH, Park SY, et al. Serum retinol-binding protein 4 levels are elevated in non-alcoholic fatty liver disease. Clin Endocrinol. 2008;68:555-560.
16. Cho YM, Youn BS, Lee H, et al. Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes. Diabetes Care. 2006;29:2457-2461.
17. Gavi S, Stuart LM, Kelly P, et al. Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes. J Clin Endocrinol Metab. 2007;92:1886-1890.
18. Lee DC, Lee JW, Im JA. Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents. Metabolism. 2007;56:327-331.
19. Yao-Borengasser A, Varma V, Bodles AM, et al. Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone. J Clin Endocrinol Metab. 2007;92:2590-2597.
20. Kanaka-Gantenbein C, Margeli A, Pervanidou P, et al. Retinol-binding protein 4 and lipocalin-2 in childhood and adolescent obesity: when children are not just ''small adults''. Clin Chem. 2008;54:1176-1182.
21. Yagmur E, Weiskirchen R, Gressner AM, et al. Insulin resistance in liver cirrhosis is not associated with circulating retinol-binding protein 4. Diabetes Care. 2007;30:1168-1172.
22. Cortez-Pinto H, de Moura MC, Day CP. Non-alcoholic steatohepatitis: from cell biology to clinical practice. J Hepatol. 2006;44:197-208.
23. Ratziu V, Charlotte F, Heurtier A, et al. Sampling variability of liver biopsy in nonalcoholic fatty liver disease. Gastroenterology. 2005;128:1898-1906.
24. Wieckowska A, Zein NN, Yerian LM, et al. In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease. Hepatology. 2006;44:27-33.
25. Wang L, Attard FA, Tankersley LR, et al. Effect of retinoic acid on the enhancing effect of acetaldehyde on mouse type I collagen expression. Arch Biochem Biophys. 2000;376:191-198.