Association between TERT-CLPTM1L rs401681[C] allele and NMSC cancer risk: A meta-analysis including 45,184 subjects

Archives of Dermatological Research

Volumn 305, Issue 1, 2013, Pages 49-52

  Yang, Xueling ^a   Yang, Baohong ^b   Li, Bo ^a   Liu, Ya ^a  

^a JILIN UNIVERSITY   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Meta analysis; rs401681 C allele; Skin cancer; TERT CLPTM1L

Indexed keywords

ALLELE; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MUTATOR GENE; NON MELANOMA SKIN CANCER; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TERT CLPTM1L GENE;

AUSTRALIA; CARCINOMA, BASAL CELL; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; EUROPE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MEMBRANE PROTEINS; NEOPLASM PROTEINS; ODDS RATIO; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SKIN NEOPLASMS; TELOMERASE; UNITED STATES;

EID: 84872306296     PISSN: 03403696     EISSN: 1432069X     Source Type: Journal    
DOI: 10.1007/s00403-012-1275-8     Document Type: Article

References (22)

1. Azuma Y, Matsukawa A (1993) Warty dyskeratoma with multiple lesions. J Dermatol 20:374-377
2. Baird DM (2010) Variation at the TERT locus and predisposition for cancer. Expert Rev Mol Med 12:e16
3. Choi JE, Kang HG, Jang JS, Choi YY, Kim MJ, Kim JS, Jeon HS, Lee WK, Cha SI, Kim CH, Kam S, Jung TH, Park JY (2009) Polymorphisms in telomere maintenance genes and risk of lung cancer. Cancer Epidem Biomar 18:2773-2781
4. Chong L, van Steensel B, Broccoli D, Erdjument-Bromage H, Hanish J, Tempst P, de Lange T (1995) A human telomeric protein. Science 270:1663-1667
5. Gilchrest BA, Eller MS, Geller AC, Yaar M (1999) The pathogenesis of melanoma induced by ultraviolet radiation. New Engl J Med 340:1341-1348
6. Han J, Qureshi AA, Prescott J, Guo Q, Ye L, Hunter DJ, De Vivo I (2009) A prospective study of telomere length and the risk of skin cancer. J Invest Dermatol 129:415-421
7. Harle-Bachor C, Boukamp P (1996) Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes. P Natl Acad Sci USA 93:6476-6481
8. Hosking FJ, Dobbins SE, Houlston RS (2011) Genome-wide association studies for detecting cancer susceptibility. Brit Med Bull 97:27-46
9. Law MH, Montgomery GW, Brown KM, Martin NG, Mann GJ, Hayward NK, MacGregor S (2012) Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk. J Invest Dermatol 132:485-487
10. Mirabello L, Yu K, Kraft P, De Vivo I, Hunter DJ, Prescott J et al (2010) The association of telomere length and genetic variation in telomere biology genes. Hum Mutat 31:1050-1058
11. Nan H, Qureshi AA, Prescott J, De Vivo I, Han J (2011) Genetic variants in telomere-maintaining genes and skin cancer risk. Hum Genet 129:247-253
12. Parris CN, Jezzard S, Silver A, MacKie R, McGregor JM, Newbold RF (1999) Telomerase activity in melanoma and non-melanoma skin cancer. Brit J Cancer 79:47-53
13. Pooley KA, Tyrer J, Shah M, Driver KE, Leyland J, Brown J et al (2010) No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk. Cancer Epidem Biomar 19:1862-1865
14. Prescott J, Wentzensen IM, Savage SA, De Vivo I (2012) Epidemiologic evidence for a role of telomere dysfunction in cancer etiology. Mutat Res 730:75-84
15. Rafnar T, Sulem P, Stacey SN, Geller F, Gudmundsson J, Sigurdsson A et al (2009) Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat Genet 41:221-227
16. Rogers HW, Weinstock MA, Harris AR, Hinckley MR, Feldman SR, Fleischer AB, Coldiron BM (2010) Incidence estimate of nonmelanoma skin cancer in the United States, 2006. Arch Dermatol 146:283-287
17. Stacey SN, Gudbjartsson DF, Sulem P, Bergthorsson JT, Kumar R, Thorleifsson G et al (2008) Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits. Nat Genet 40:1313-1318
18. Stacey SN, Sulem P, Masson G, Gudjonsson SA, Thorleifsson G, Jakobsdottir M et al (2009) New common variants affecting susceptibility to basal cell carcinoma. Nat Genet 41:909-914
19. Taylor RS, Ramirez RD, Ogoshi M, Chaffins M, Piatyszek MA, Shay JW (1996) Detection of telomerase activity in malignant and nonmalignant skin conditions. J Invest Dermatol 106:759-765
20. Wang Y, Broderick P, Webb E, Wu X, Vijayakrishnan J, Matakidou A, Qureshi M, Dong Q, Gu X, Chen WV, Spitz MR, Eisen T, Amos CI, Houlston RS (2008) Common 5p15.33 and 6p21.33 variants influence lung cancer risk. Nat Genet 40:1407-1409
21. Wu A, Ichihashi M, Ueda M (1999) Correlation of the expression of human telomerase subunits with telomerase activity in normal skin and skin tumors. Cancer 86:2038-2044
22. Zienolddiny S, Skaug V, Landvik NE, Ryberg D, Phillips DH, Houlston R, Haugen A (2009) The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung. Carcinogenesis 30:1368-1371