TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin

Biochemical and Biophysical Research Communications

Volumn 430, Issue 2, 2013, Pages 664-669

  Naka, Ayano ^a,c   Iida, Kaoruko Tada ^a,b   Nakagawa, Yoshimi ^a   Iwasaki, Hitoshi ^a   Takeuchi, Yoshinori ^a   Satoh, Aoi ^a   Matsuzaka, Takashi ^a   Ishii, Kiyo Aki ^a   Kobayashi, Kazuto ^a   Yatoh, Shigeru ^a   Shimada, Masako ^a   Yahagi, Naoya ^a   Suzuki, Hiroaki ^a   Sone, Hirohito ^a   Yamada, Nobuhiro ^a   Shimano, Hitoshi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b OCHANOMIZU UNIVERSITY   (Japan)

^c JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

Author keywords

Myoblast differentiation; Myogenic regulatory factors; Myogenin; Transcription factor E3

Indexed keywords

MYOD PROTEIN; MYOGENIN; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E3; UNCLASSIFIED DRUG;

ADENOVIRUS; ARTICLE; BINDING KINETICS; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; E BOX ELEMENT; GEL MOBILITY SHIFT ASSAY; HOMOLOGOUS RECOMBINATION; INHIBITION KINETICS; MYOBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SKELETAL MUSCLE; TRANSCRIPTION REGULATION;

ANIMALS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL LINE; DOWN-REGULATION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; MICE; MYOBLASTS; MYOD PROTEIN; MYOGENIC REGULATORY FACTOR 5; MYOGENIN;

ADENOVIRIDAE; ANIMALIA;

EID: 84872287518     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.11.094     Document Type: Article

References (26)

1. Beckmann H., Su L.K., Kadesch T. TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif. Gene. Dev. 1990, 4:167-179.
2. Hershey C.L., Fisher D.E. Mitf and Tfe3: members of a b-HLH-ZIP transcription factor family essential for osteoclast development and function. Bone 2004, 34:689-696.
3. Verastegui C., Bertolotto C., Bille K., Abbe P., Ortonne J.P., Ballotti R. TFE3, a transcription factor homologous to microphthalmia, is a potential transcriptional activator of tyrosinase and TyrpI genes. Mol. Endocrinol. 2000, 14:449-456.
4. Steingrimsson E., Tessarollo L., Pathak B., Hou L., Arnheiter H., Copeland N.G., Jenkins N.A. Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development. Proc. Natl. Acad. Sci. USA 2002, 99:4477-4482.
5. Hemesath T.J., Steingrimsson E., McGill G., Hansen M.J., Vaught J., Hodgkinson C.A., Arnheiter H., Copeland N.G., Jenkins N.A., Fisher D.E. Microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family. Gene. Dev. 1994, 8:2770-2780.
6. Nakagawa Y., Shimano H., Yoshikawa T., Ide T., Tamura M., Furusawa M., Yamamoto T., Inoue N., Matsuzaka T., Takahashi A., Hasty A.H., Suzuki H., Sone H., Toyoshima H., Yahagi N., Yamada N. TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes. Nat. Med. 2006, 12:107-113.
7. Iwasaki H., Naka A., Iida K.T., Nakagawa Y., Matsuzaka T., Ishii K.A., Kobayashi K., Takahashi A., Yatoh S., Yahagi N., Sone H., Suzuki H., Yamada N., Shimano H. TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice. Am. J. Physiol. Endocrinol. Metab. 2012, 302:E896-E902.
8. Ooishi R., Shirai M., Funaba M., Murakami M. Microphthalmia-associated transcription factor is required for mature myotube formation. Biochim. Biophys. Acta 1820, 2012:76-83.
9. Olson E.N., Klein W.H. bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out. Gene. Dev. 1994, 8:1-8.
10. Olson E.N., Rosenthal N. Homeobox genes and muscle patterning. Cell 1994, 79:9-12.
11. Berkes C.A., Tapscott S.J. MyoD and the transcriptional control of myogenesis. Semin. Cell Dev. Biol. 2005, 16:585-595.
12. Fujimoto Y., Nakagawa Y., Shingyouchi A., Tokushige N., Nakanishi N., Satoh A., Matsuzaka T., Ishii K.A., Iwasaki H., Kobayashi K., Yatoh S., Suzuki H., Yahagi N., Urayama O., Yamada N., Shimano H. Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in 3T3-L1 cells. Biochem. Biophys. Res. Commun. 2012, 420:931-936.
13. Edmondson D.G., Cheng T.C., Cserjesi P., Chakraborty T., Olson E.N. Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2. Mol. Cell. Biol. 1992, 12:3665-3677.
14. Ide T., Shimano H., Yahagi N., Matsuzaka T., Nakakuki M., Yamamoto T., Nakagawa Y., Takahashi A., Suzuki H., Sone H., Toyoshima H., Fukamizu A., Yamada N. SREBPs suppress IRS-2-mediated insulin signalling in the liver. Nat. Cell Biol. 2004, 6:351-357.
15. Morgan J.E., Moore S.E., Walsh F.S., Partridge T.A. Formation of skeletal muscle in vivo from the mouse C2 cell line. J. Cell Sci. 1992, 102(Pt 4):779-787.
16. Moore K.J. Insight into the microphthalmia gene. Trends Genet. 1995, 11:442-448.
17. Hasty P., Bradley A., Morris J.H., Edmondson D.G., Venuti J.M., Olson E.N., Klein W.H. Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene. Nature 1993, 364:501-506.
18. Nabeshima Y., Hanaoka K., Hayasaka M., Esumi E., Li S., Nonaka I. Myogenin gene disruption results in perinatal lethality because of severe muscle defect. Nature 1993, 364:532-535.
19. Mal A., Harter M.L. MyoD is functionally linked to the silencing of a muscle-specific regulatory gene prior to skeletal myogenesis. Proc. Natl. Acad. Sci. USA 2003, 100:1735-1739.
20. Malik S., Huang C.F., Schmidt J. The role of the CANNTG promoter element (E box) and the myocyte-enhancer-binding-factor-2 (MEF-2) site in the transcriptional regulation of the chick myogenin gene. Eur. J. Biochem. 1995, 230:88-96.
21. Parker M.H., Perry R.L., Fauteux M.C., Berkes C.A., Rudnicki M.A. MyoD synergizes with the E-protein HEB beta to induce myogenic differentiation. Mol. Cell. Biol. 2006, 26:5771-5783.
22. Giangrande P.H., Hallstrom T.C., Tunyaplin C., Calame K., Nevins J.R. Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor. Mol. Cell. Biol. 2003, 23:3707-3720.
23. Grinberg A.V., Kerppola T. Both Max and TFE3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter, but they have opposite effects on transcriptional activity. J. Biol. Chem. 2003, 278:11227-11236.
24. Hua X., Liu X., Ansari D.O., Lodish H.F. Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene. Gene. Dev. 1998, 12:3084-3095.
25. Feinman R., Qiu W.Q., Pearse R.N., Nikolajczyk B.S., Sen R., Sheffery M., Ravetch J.V. PU.1 and an HLH family member contribute to the myeloid-specific transcription of the Fc gamma RIIIA promoter. EMBO J. 1994, 13:3852-3860.
26. Liu D., Black B.L., Derynck R. TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Gene. Dev. 2001, 15:2950-2966.