-
1
-
-
73649108979
-
L’hibernation artificielle par moyens pharmacodynamiques et physiques
-
Laborit H, Huguenard P. L’hibernation artificielle par moyens pharmacodynamiques et physiques. Presse Med 1951; 59:1329.
-
(1951)
Presse Med
, vol.59
, pp. 1329
-
-
Laborit, H.1
Huguenard, P.2
-
2
-
-
78651116398
-
Effect of chlorpromazine or haloperidol on formation of 3-methoxytyramine and normetanephrine in mouse brain
-
Carlsson A, Lindqvist M. Effect of chlorpromazine or haloperidol on formation of 3-methoxytyramine and normetanephrine in mouse brain. Acta Pharmacol Toxicol 1963; 20:140-144.
-
(1963)
Acta Pharmacol Toxicol
, vol.20
, pp. 140-144
-
-
Carlsson, A.1
Lindqvist, M.2
-
3
-
-
0001325136
-
Effects of chlorpromazine, haloperidol, and reserpine on the levels of phenolic acids in rabbit corpus striatum
-
Anden NE, Roos BE, Werdinius B. Effects of chlorpromazine, haloperidol, and reserpine on the levels of phenolic acids in rabbit corpus striatum. Life Sci 1964; 3:149.
-
(1964)
Life Sci
, vol.3
, pp. 149
-
-
Anden, N.E.1
Roos, B.E.2
Werdinius, B.3
-
4
-
-
0014717325
-
Receptor activity and turnover of dopamine and noradrenaline after neuroleptics
-
Anden NE, Butcher SG, Corrodi H, Fuxe K, Ungerstedt U. Receptor activity and turnover of dopamine and noradrenaline after neuroleptics. Eur J Pharmacol 1970; 11:303-314.
-
(1970)
Eur J Pharmacol
, vol.11
, pp. 303-314
-
-
Anden, N.E.1
Butcher, S.G.2
Corrodi, H.3
Fuxe, K.4
Ungerstedt, U.5
-
5
-
-
0033045962
-
A historical perspective of clozapine
-
Hippius H. A historical perspective of clozapine. J Clin Psychiatry 1999; 60 (suppl 12):22-23.
-
(1999)
J Clin Psychiatry
, vol.60
, pp. 22-23
-
-
Hippius, H.1
-
6
-
-
0032722202
-
A history of antipsychotic drug development
-
Shen WW. A history of antipsychotic drug development. Compr Psychiatry 1999; 40:407-414.
-
(1999)
Compr Psychiatry
, vol.40
, pp. 407-414
-
-
Shen, W.W.1
-
8
-
-
0023812652
-
Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine
-
Kane J, Honigfeld G, Singer J, Meltzer H. Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Arch Gen Psychiatry 1988; 45:789-796.
-
(1988)
Arch Gen Psychiatry
, vol.45
, pp. 789-796
-
-
Kane, J.1
Honigfeld, G.2
Singer, J.3
Meltzer, H.4
-
9
-
-
0036357466
-
Action of atypical antipsychotics
-
Meltzer HY. Action of atypical antipsychotics. Am J Psychiatry 2002; 159: 153-154.
-
(2002)
Am J Psychiatry
, vol.159
, pp. 153-154
-
-
Meltzer, H.Y.1
-
10
-
-
0018192714
-
Antagonism of fenfluramine-induced hyperthermia: A measure of central serotonin inhibition
-
Sulpizio A, Fowler PJ, Macko E. Antagonism of fenfluramine-induced hyperthermia: a measure of central serotonin inhibition. Life Sci 1978; 22:1439-1446.
-
(1978)
Life Sci
, vol.22
, pp. 1439-1446
-
-
Sulpizio, A.1
Fowler, P.J.2
Macko, E.3
-
11
-
-
0022922681
-
Typical and atypical antipsychotic occupancy of D2 and S2 receptors: An autoradiographic analysis in rat brain
-
Altar CA, Wasley AM, Neale RF, Stone GA. Typical and atypical antipsychotic occupancy of D2 and S2 receptors: an autoradiographic analysis in rat brain. Brain Res Bull 1986 16:517-525.
-
(1986)
Brain Res Bull
, vol.16
, pp. 517-525
-
-
Altar, C.A.1
Wasley, A.M.2
Neale, R.F.3
Stone, G.A.4
-
12
-
-
0016703549
-
Serotonergic involvement with neuroleptic catalepsy
-
Costall B, Fortune DH, Naylor RJ, Mardsen CD, Pycock C. Serotonergic involvement with neuroleptic catalepsy. Neuropharmacology 1975; 14:859-868.
-
(1975)
Neuropharmacology
, vol.14
, pp. 859-868
-
-
Costall, B.1
Fortune, D.H.2
Naylor, R.J.3
Mardsen, C.D.4
Pycock, C.5
-
13
-
-
0018143206
-
Neuroleptic interaction with the serotoninergic-dopaminergic mechanisms in the nucleus accumbens
-
Costall B, Naylor RJ. Neuroleptic interaction with the serotoninergic-dopaminergic mechanisms in the nucleus accumbens. J Pharm Pharmacol 1978; 30:257-259.
-
(1978)
J Pharm Pharmacol
, vol.30
, pp. 257-259
-
-
Costall, B.1
Naylor, R.J.2
-
14
-
-
0025572228
-
5-HT2 antagonist ritanserin in neuroleptic-induced parkinsonism: A double-blind comparison with orphenadrine and placebo
-
Bersani G, Grispini A, Marini S, Pasini A, Valducci M, Ciani N. 5-HT2 antagonist ritanserin in neuroleptic-induced parkinsonism: a double-blind comparison with orphenadrine and placebo. Clin Neuropharmacol 1990; 13:500-506.
-
(1990)
Clin Neuropharmacol
, vol.13
, pp. 500-506
-
-
Bersani, G.1
Grispini, A.2
Marini, S.3
Pasini, A.4
Valducci, M.5
Ciani, N.6
-
15
-
-
0021943587
-
Effect of serotonin antagonism in schizophrenia: A pilot study with setoperone
-
Ceulemans DL, Gelders YG, Hoppenbrouwers ML, Reyntjens AJ, Janssen PA. Effect of serotonin antagonism in schizophrenia: a pilot study with setoperone. Psychopharmacology (Berl) 1985; 85:329-332.
-
(1985)
Psychopharmacology (Berl)
, vol.85
, pp. 329-332
-
-
Ceulemans, D.L.1
Gelders, Y.G.2
Hoppenbrouwers, M.L.3
Reyntjens, A.J.4
Janssen, P.A.5
-
16
-
-
0036365725
-
Commentary on “Clinical studies on the mechanism of action of clozapine; the dopamine-serotonin hypothesis of schizophrenia in Psychopharmacology 1989"
-
99:S18-S27
-
Meltzer HY. Commentary on “Clinical studies on the mechanism of action of clozapine; the dopamine-serotonin hypothesis of schizophrenia in Psychopharmacology 1989"; 99:S18-S27; Psychopharmacology (Berl) 2002; 163:1-3.
-
(2002)
Psychopharmacology (Berl)
, vol.163
, pp. 1-3
-
-
Meltzer, H.Y.1
-
17
-
-
0020576408
-
Typical and atypical neuroleptics: Differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons
-
Chiodo LA, Bunney BS. Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons. J Neurosci 1983; 3:1607-1619.
-
(1983)
J Neurosci
, vol.3
, pp. 1607-1619
-
-
Chiodo, L.A.1
Bunney, B.S.2
-
18
-
-
0343390079
-
Clozapine: Mechanism of action in relation to its clinical advantages
-
Kales A, Stefanos CN, Talbott JA (eds), New York: Springer-Verlag
-
Meltzer HY. Clozapine: mechanism of action in relation to its clinical advantages. In: Kales A, Stefanos CN, Talbott JA (eds) Recent advances in Schizophrenia. New York: Springer-Verlag, 1990.
-
(1990)
Recent advances in Schizophrenia
-
-
Meltzer, H.Y.1
-
19
-
-
0024468417
-
Clinical studies on the mechanism of action of clozapine: The dopamineserotonin hypothesis of schizophrenia
-
Meltzer HY. Clinical studies on the mechanism of action of clozapine: the dopamineserotonin hypothesis of schizophrenia. Psychopharmacology (Berl) 1989; 99 (Suppl):S18-S27.
-
(1989)
Psychopharmacology (Berl)
, vol.99
, pp. S18-S27
-
-
Meltzer, H.Y.1
-
20
-
-
0035098915
-
Landmark publications in Psychopharmacology: The first 40 years
-
Miczek KA. Landmark publications in Psychopharmacology: the first 40 years. Psychopharmacology (Berl) 2001; 153:399-401.
-
(2001)
Psychopharmacology (Berl)
, vol.153
, pp. 399-401
-
-
Miczek, K.A.1
-
21
-
-
0024466603
-
Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values
-
Meltzer HY, Matsubara S, Lee JC. Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values. J Pharmacol Exp Ther 1989; 251:238-246.
-
(1989)
J Pharmacol Exp Ther
, vol.251
, pp. 238-246
-
-
Meltzer, H.Y.1
Matsubara, S.2
Lee, J.C.3
-
22
-
-
0004243123
-
-
9th edn, Baltimore: Williams and Wilkins
-
Parent A. Human Neuroanatomy, 9th edn, Baltimore: Williams and Wilkins, 1995.
-
(1995)
Human Neuroanatomy
-
-
Parent, A.1
-
23
-
-
0023274497
-
Serotonin receptors in the human brain-IV. Autoradiographic mapping of serotonin-2 receptors
-
Pazos A, Probst A, Palacios JM. Serotonin receptors in the human brain-IV. Autoradiographic mapping of serotonin-2 receptors. Neuroscience 1987; 21:123-139.
-
(1987)
Neuroscience
, vol.21
, pp. 123-139
-
-
Pazos, A.1
Probst, A.2
Palacios, J.M.3
-
24
-
-
0024478415
-
Ritanserin, a 5-HT2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition
-
Ugedo L, Grenhoff J, Svensson TH. Ritanserin, a 5-HT2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition. Psychopharmacology (Berl) 1989; 98:45-50.
-
(1989)
Psychopharmacology (Berl)
, vol.98
, pp. 45-50
-
-
Ugedo, L.1
Grenhoff, J.2
Svensson, T.H.3
-
25
-
-
0026070134
-
Dopamine in schizophrenia: A review and reconceptualization
-
Davis KL, Kahn RS, Ko G, Davidson M. Dopamine in schizophrenia: a review and reconceptualization. Am J Psychiatry 1991; 148:1474-1486.
-
(1991)
Am J Psychiatry
, vol.148
, pp. 1474-1486
-
-
Davis, K.L.1
Kahn, R.S.2
Ko, G.3
Davidson, M.4
-
26
-
-
0030964194
-
Dopamine, the prefrontal cortex and schizophrenia
-
Knable MB, Weinberger DR. Dopamine, the prefrontal cortex and schizophrenia. J Psychopharmacol 1997; 11:123-131.
-
(1997)
J Psychopharmacol
, vol.11
, pp. 123-131
-
-
Knable, M.B.1
Weinberger, D.R.2
-
27
-
-
0029930927
-
Risperidone compared with new and reference antipsychotic drugs: In vitro and in vivo receptor binding
-
Schotte A, Janssen PF, Gommeren W, Luyten WH, Van Gompel P, Lesage AS, De Loore K, Leysen JE. Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl) 1996; 124:57-73.
-
(1996)
Psychopharmacology (Berl)
, vol.124
, pp. 57-73
-
-
Schotte, A.1
Janssen, P.F.2
Gommeren, W.3
Luyten, W.H.4
Van Gompel, P.5
Lesage, A.S.6
De Loore, K.7
Leysen, J.E.8
-
28
-
-
0027248858
-
Seroquel: Biochemical profile of a potential atypical antipsychotic
-
Saller CF, Salama AI. Seroquel: biochemical profile of a potential atypical antipsychotic. Psychopharmacology (Berl) 1993; 112:285-292.
-
(1993)
Psychopharmacology (Berl)
, vol.112
, pp. 285-292
-
-
Saller, C.F.1
Salama, A.I.2
-
29
-
-
85083276684
-
Atypical antipsychotics
-
The Fourth Generation of Progress Online Edition. American College of Neuropsychopharmacology
-
Meltzer HY. Atypical antipsychotics. In: Psychopharmacology, The Fourth Generation of Progress Online Edition. American College of Neuropsychopharmacology 2000. www.acnp.org/g4.
-
(2000)
Psychopharmacology
-
-
Meltzer, H.Y.1
-
30
-
-
0036221550
-
Atypical antipsychotics: Mechanism of action
-
Seeman P. Atypical antipsychotics: mechanism of action. Can J Psychiatry 2002; 47:27-38.
-
(2002)
Can J Psychiatry
, vol.47
, pp. 27-38
-
-
Seeman, P.1
-
31
-
-
2642638739
-
Binding of antipsychotic drugs to cortical 5-HT2A receptors: A PET study of chlorpromazine, clozapine, and amisulpride in schizophrenic patients
-
Trichard C, Paillere-Martinot ML, Attar-Levy D, Recassens C, Monnet F, Martinot JL. Binding of antipsychotic drugs to cortical 5-HT2A receptors: a PET study of chlorpromazine, clozapine, and amisulpride in schizophrenic patients. Am J Psychiatry 1998; 155:505-508.
-
(1998)
Am J Psychiatry
, vol.155
, pp. 505-508
-
-
Trichard, C.1
Paillere-Martinot, M.L.2
Attar-Levy, D.3
Recassens, C.4
Monnet, F.5
Martinot, J.L.6
-
32
-
-
19644400504
-
Author reply to Meltzer HY: Action of atypical antipsychotics
-
Kapur S, Seeman P. Author reply to Meltzer HY: Action of atypical antipsychotics. Am J Psychiatry 2002; 159:153-155.
-
(2002)
Am J Psychiatry
, vol.159
, pp. 153-155
-
-
Kapur, S.1
Seeman, P.2
-
33
-
-
0034025771
-
Relationship between dopamine D(2) occupancy, clinical response, and side effects: A double-blind PET study of first-episode schizophrenia
-
Kapur S, Zipursky R, Jones C, Remington G, Houle S. Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia. Am J Psychiatry 2000; 157:514-520.
-
(2000)
Am J Psychiatry
, vol.157
, pp. 514-520
-
-
Kapur, S.1
Zipursky, R.2
Jones, C.3
Remington, G.4
Houle, S.5
-
34
-
-
0026718710
-
Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects
-
Farde L, Nordstrom AL, Wiesel FA, Pauli S, Halldin C, Sedvall G. Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects. Arch Gen Psychiatry 1992; 49:538-544.
-
(1992)
Arch Gen Psychiatry
, vol.49
, pp. 538-544
-
-
Farde, L.1
Nordstrom, A.L.2
Wiesel, F.A.3
Pauli, S.4
Halldin, C.5
Sedvall, G.6
-
35
-
-
0027520871
-
Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients
-
Nordstrom AL, Farde L, Wiesel FA, Forslund K, Pauli S, Halldin C, Uppfeldt G. Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: a double-blind PET study of schizophrenic patients. Biol Psychiatry 1993; 33:227-235.
-
(1993)
Biol Psychiatry
, vol.33
, pp. 227-235
-
-
Nordstrom, A.L.1
Farde, L.2
Wiesel, F.A.3
Forslund, K.4
Pauli, S.5
Halldin, C.6
Uppfeldt, G.7
-
36
-
-
0032587533
-
In vivo 123I IBZM SPECT imaging of striatal dopamine-2 receptor occupancy in schizophrenic patients treated with olanzapine in comparison to clozapine and haloperidol
-
Tauscher J, Kufferle B, Asenbaum S, Fischer P, Pezawas L, Barnas C, Tauscher-Wisniewski S, Brucke T, Kasper S. In vivo 123I IBZM SPECT imaging of striatal dopamine-2 receptor occupancy in schizophrenic patients treated with olanzapine in comparison to clozapine and haloperidol. Psychopharmacology (Berl) 1999; 141:175-181.
-
(1999)
Psychopharmacology (Berl)
, vol.141
, pp. 175-181
-
-
Tauscher, J.1
Kufferle, B.2
Asenbaum, S.3
Fischer, P.4
Pezawas, L.5
Barnas, C.6
Tauscher-Wisniewski, S.7
Brucke, T.8
Kasper, S.9
-
37
-
-
0030770818
-
Extrapyramidal side effects with risperidone and haloperidol at comparable D2 receptor occupancy levels
-
Knable MB, Heinz A, Raedler T, Weinberger DR. Extrapyramidal side effects with risperidone and haloperidol at comparable D2 receptor occupancy levels. Psychiatry Res 1997; 75:91-101.
-
(1997)
Psychiatry Res
, vol.75
, pp. 91-101
-
-
Knable, M.B.1
Heinz, A.2
Raedler, T.3
Weinberger, D.R.4
-
38
-
-
0027239726
-
Dose dependent occupancy of central dopamine D2 receptors by the novel neuroleptic CP-88, 059-01: A study using positron emission tomography and 11C-raclopride
-
Bench CJ, Lammertsma AA, Dolan RJ, Grasby PM, Warrington SJ, Gunn K, Cuddigan M, Turton DJ, Osman S, Frackowiak RS. Dose dependent occupancy of central dopamine D2 receptors by the novel neuroleptic CP-88, 059-01: a study using positron emission tomography and 11C-raclopride. Psychopharmacology (Berl) 1993; 112:308-314.
-
(1993)
Psychopharmacology (Berl)
, vol.112
, pp. 308-314
-
-
Bench, C.J.1
Lammertsma, A.A.2
Dolan, R.J.3
Grasby, P.M.4
Warrington, S.J.5
Gunn, K.6
Cuddigan, M.7
Turton, D.J.8
Osman, S.9
Frackowiak, R.S.10
-
39
-
-
0034091239
-
A positron emission tomography study of quetiapine in schizophrenia: A preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy
-
Kapur S, Zipursky R, Jones C, Shammi CS, Remington G, Seeman P. A positron emission tomography study of quetiapine in schizophrenia: a preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy. Arch Gen Psychiatry 2000; 57:553-559.
-
(2000)
Arch Gen Psychiatry
, vol.57
, pp. 553-559
-
-
Kapur, S.1
Zipursky, R.2
Jones, C.3
Shammi, C.S.4
Remington, G.5
Seeman, P.6
-
40
-
-
0036855229
-
Quetiapine: An effective antipsychotic in first-episode schizophrenia despite only transiently high dopamine-2 receptor blockade
-
Tauscher-Wisniewski S, Kapur S, Tauscher J, Jones C, Daskalakis ZJ, Papatheodorou G, Epstein I, Christensen BK, Zipursky RB. Quetiapine: an effective antipsychotic in first-episode schizophrenia despite only transiently high dopamine-2 receptor blockade. J Clin Psychiatry 2002; 63:992-997.
-
(2002)
J Clin Psychiatry
, vol.63
, pp. 992-997
-
-
Tauscher-Wisniewski, S.1
Kapur, S.2
Tauscher, J.3
Jones, C.4
Daskalakis, Z.J.5
Papatheodorou, G.6
Epstein, I.7
Christensen, B.K.8
Zipursky, R.B.9
-
41
-
-
0036176043
-
Clozapine can induce high dopamine D(2) receptor occupancy in vivo
-
Suhara T, Okauchi T, Sudo Y, Takano A, Kawabe K, Maeda J, Kapur S. Clozapine can induce high dopamine D(2) receptor occupancy in vivo. Psychopharmacology (Berl) 2002; 160:107-112.
-
(2002)
Psychopharmacology (Berl)
, vol.160
, pp. 107-112
-
-
Suhara, T.1
Okauchi, T.2
Sudo, Y.3
Takano, A.4
Kawabe, K.5
Maeda, J.6
Kapur, S.7
-
42
-
-
0037035393
-
Increasing D2 affinity results in the loss of clozapine’s atypical antipsychotic action
-
Kapur S, McClelland RA, VanderSpek SC, Wadenberg ML, Baker G, Nobrega J, Zipursky RB, Seeman P. Increasing D2 affinity results in the loss of clozapine’s atypical antipsychotic action. Neuroreport 2002; 13:831-835.
-
(2002)
Neuroreport
, vol.13
, pp. 831-835
-
-
Kapur, S.1
McClelland, R.A.2
VanderSpek, S.C.3
Wadenberg, M.L.4
Baker, G.5
Nobrega, J.6
Zipursky, R.B.7
Seeman, P.8
-
43
-
-
0035094264
-
Does fast dissociation from the dopamine d(2) receptor explain the action of atypical antipsychotics?: A new hypothesis
-
Kapur S, Seeman P. Does fast dissociation from the dopamine d(2) receptor explain the action of atypical antipsychotics?: A new hypothesis. Am J Psychiatry 2001; 158:360-369.
-
(2001)
Am J Psychiatry
, vol.158
, pp. 360-369
-
-
Kapur, S.1
Seeman, P.2
-
44
-
-
0034109940
-
Antipsychotic agents differ in how fast they come off the dopamine D2 receptors. Implications for atypical antipsychotic action
-
Kapur S, Seeman P. Antipsychotic agents differ in how fast they come off the dopamine D2 receptors. Implications for atypical antipsychotic action. J Psychiatry Neurosci 2000; 25:161-166.
-
(2000)
J Psychiatry Neurosci
, vol.25
, pp. 161-166
-
-
Kapur, S.1
Seeman, P.2
-
45
-
-
0035660215
-
Dopamine D(2) receptors and their role in atypical antipsychotic action: Still necessary and may even be sufficient
-
Kapur S, Remington G. Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient. Biol Psychiatry 2001; 50:873-883.
-
(2001)
Biol Psychiatry
, vol.50
, pp. 873-883
-
-
Kapur, S.1
Remington, G.2
-
46
-
-
0027297275
-
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
-
Lefkowitz RJ, Cotecchia S, Samama P, Costa T. Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol Sci 1993; 14:303-307.
-
(1993)
Trends Pharmacol Sci
, vol.14
, pp. 303-307
-
-
Lefkowitz, R.J.1
Cotecchia, S.2
Samama, P.3
Costa, T.4
-
47
-
-
0033012934
-
Agonism and inverse agonism at dopamine D2-like receptors
-
Strange PG. Agonism and inverse agonism at dopamine D2-like receptors. Clin Exp Pharmacol Physiol Suppl 1999; 26:S3-S9.
-
(1999)
Clin Exp Pharmacol Physiol Suppl
, vol.26
, pp. S3-S9
-
-
Strange, P.G.1
-
48
-
-
0035101404
-
Antipsychotic drugs: Importance of dopamine receptors for mechanisms of therapeutic actions and side effects
-
Strange PG. Antipsychotic drugs: importance of dopamine receptors for mechanisms of therapeutic actions and side effects. Pharmacol Rev 2001; 53:119-133.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 119-133
-
-
Strange, P.G.1
-
49
-
-
0034806737
-
Inverse agonist actions of typical and atypical antipsychotic drugs at the human 5-hydroxytryptamine(2C) receptor
-
Rauser L, Savage JE, Meltzer HY, Roth BL. Inverse agonist actions of typical and atypical antipsychotic drugs at the human 5-hydroxytryptamine(2C) receptor. J Pharmacol Exp Ther 2001; 299:83-89.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 83-89
-
-
Rauser, L.1
Savage, J.E.2
Meltzer, H.Y.3
Roth, B.L.4
-
50
-
-
0344068742
-
Apomorphine as a hypnotic
-
Douglas CJ. Apomorphine as a hypnotic. NY Med J 1900; 71:376.
-
(1900)
NY Med J
, vol.71
, pp. 376
-
-
Douglas, C.J.1
-
51
-
-
0015395790
-
Evidence for a receptormediated feedback control of striatal tyrosine hydroxylase activity
-
Kehr W, Carlsson A, Lindqvist M, Magnusson T, Atack C. Evidence for a receptormediated feedback control of striatal tyrosine hydroxylase activity. J Pharm Pharmacol 1972; 24:744-747.
-
(1972)
J Pharm Pharmacol
, vol.24
, pp. 744-747
-
-
Kehr, W.1
Carlsson, A.2
Lindqvist, M.3
Magnusson, T.4
Atack, C.5
-
53
-
-
0018907255
-
Bromocriptine and CF 25-397 in the treatment of tardive dyskinesia
-
Tamminga CA, Chase TN. Bromocriptine and CF 25-397 in the treatment of tardive dyskinesia. Arch Neurol 1980; 37:204-205.
-
(1980)
Arch Neurol
, vol.37
, pp. 204-205
-
-
Tamminga, C.A.1
Chase, T.N.2
-
54
-
-
0022515634
-
Dopamine agonist treatment of schizophrenia with N-propylnorapomorphine
-
Tamminga CA, Gotts MD, Thaker GK, Alphs LD, Foster NL. Dopamine agonist treatment of schizophrenia with N-propylnorapomorphine. Arch Gen Psychiatry 1986; 43:398-402.
-
(1986)
Arch Gen Psychiatry
, vol.43
, pp. 398-402
-
-
Tamminga, C.A.1
Gotts, M.D.2
Thaker, G.K.3
Alphs, L.D.4
Foster, N.L.5
-
55
-
-
0036202379
-
Partial dopamine agonists in the treatment of psychosis
-
Tamminga CA. Partial dopamine agonists in the treatment of psychosis. J Neural Transm 2002; 109:411-20.
-
(2002)
J Neural Transm
, vol.109
, pp. 411-420
-
-
Tamminga, C.A.1
-
56
-
-
0026632497
-
Pharmacologic properties of (-)-3PPP (preclamol) in man
-
Tamminga CA, Cascella NG, Lahti RA, Lindberg M, Carlsson A. Pharmacologic properties of (-)-3PPP (preclamol) in man. J Neural Transm Gen Sect 1992; 88:165-175.
-
(1992)
J Neural Transm Gen Sect
, vol.88
, pp. 165-175
-
-
Tamminga, C.A.1
Cascella, N.G.2
Lahti, R.A.3
Lindberg, M.4
Carlsson, A.5
-
57
-
-
0031963973
-
Antipsychotic properties of the partial dopamine agonist (-)-3-(3-hydroxyphenyl)-N-npropylpiperidine (preclamol) in schizophrenia
-
Lahti AC, Weiler MA, Corey PK, Lahti RA, Carlsson A, Tamminga CA. Antipsychotic properties of the partial dopamine agonist (-)-3-(3-hydroxyphenyl)-N-npropylpiperidine (preclamol) in schizophrenia. Biol Psychiatry 1998; 43:2-11.
-
(1998)
Biol Psychiatry
, vol.43
, pp. 2-11
-
-
Lahti, A.C.1
Weiler, M.A.2
Corey, P.K.3
Lahti, R.A.4
Carlsson, A.5
Tamminga, C.A.6
-
58
-
-
0023839434
-
Effect of 7-(3-[4-(2, 3-dimethylphenyl) piperazinyl] propoxy)-2(1H)-quinolinone (OPC-4392), a newly synthesized agonist for presynaptic dopamine D2 receptor, on tyrosine hydroxylation in rat striatal slices
-
Kiuchi K, Hirata Y, Minami M, Nagatsu T. Effect of 7-(3-[4-(2, 3-dimethylphenyl) piperazinyl] propoxy)-2(1H)-quinolinone (OPC-4392), a newly synthesized agonist for presynaptic dopamine D2 receptor, on tyrosine hydroxylation in rat striatal slices. Life Sci 1988; 42:343-349.
-
(1988)
Life Sci
, vol.42
, pp. 343-349
-
-
Kiuchi, K.1
Hirata, Y.2
Minami, M.3
Nagatsu, T.4
-
59
-
-
0029023002
-
7-(4-[4-(2,3-Dichlorophenyl)-1-piperazinyl] butyloxy)-3,4-dihydro-2(1H)-quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity
-
Kikuchi T, Tottori K, Uwahodo Y, Hirose T, Miwa T, Oshiro Y, Morita S. 7-(4-[4-(2,3-Dichlorophenyl)-1-piperazinyl] butyloxy)-3,4-dihydro-2(1H)-quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity. J Pharmacol Exp Ther 1995; 274:329-336.
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 329-336
-
-
Kikuchi, T.1
Tottori, K.2
Uwahodo, Y.3
Hirose, T.4
Miwa, T.5
Oshiro, Y.6
Morita, S.7
-
60
-
-
0035983682
-
Dopamine D2 and D3 receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597): A study using positron emission tomography and [11C]raclopride
-
Yokoi F, Grunder G, Biziere K, Stephane M, Dogan AS, Dannals RF, Ravert H, Suri A, Bramer S, Wong DF. Dopamine D2 and D3 receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597): a study using positron emission tomography and [11C]raclopride. Neuropsychopharmacology 2002; 27:248-259.
-
(2002)
Neuropsychopharmacology
, vol.27
, pp. 248-259
-
-
Yokoi, F.1
Grunder, G.2
Biziere, K.3
Stephane, M.4
Dogan, A.S.5
Dannals, R.F.6
Ravert, H.7
Suri, A.8
Bramer, S.9
Wong, D.F.10
-
61
-
-
0029083875
-
Why does clozapine stimulate the motor activity of reserpine-pretreated rats when combined with a dopamine D1 receptor agonist?
-
Jackson DM, Mohell N, Bengtsson A, Malmberg A. Why does clozapine stimulate the motor activity of reserpine-pretreated rats when combined with a dopamine D1 receptor agonist? Eur J Pharmacol 1995; 282:137-144.
-
(1995)
Eur J Pharmacol
, vol.282
, pp. 137-144
-
-
Jackson, D.M.1
Mohell, N.2
Bengtsson, A.3
Malmberg, A.4
-
62
-
-
0031973531
-
Partial agonistic action of clozapine at dopamine D2 receptors in dopamine depleted animals
-
Ninan I, Kulkarni SK. Partial agonistic action of clozapine at dopamine D2 receptors in dopamine depleted animals. Psychopharmacology (Berl) 1998; 135:311-317.
-
(1998)
Psychopharmacology (Berl)
, vol.135
, pp. 311-317
-
-
Ninan, I.1
Kulkarni, S.K.2
-
63
-
-
0034628971
-
The effect of serotonin(1A) receptor agonism on antipsychotic drug-induced dopamine release in rat striatum and nucleus accumbens
-
Ichikawa J, Meltzer HY. The effect of serotonin(1A) receptor agonism on antipsychotic drug-induced dopamine release in rat striatum and nucleus accumbens. Brain Res 2000; 858:252-263.
-
(2000)
Brain Res
, vol.858
, pp. 252-263
-
-
Ichikawa, J.1
Meltzer, H.Y.2
-
64
-
-
0035096016
-
5-HT (2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: A possible mechanism of atypical antipsychotic-induced cortical dopamine release
-
Ichikawa J, Ishii H, Bonaccorso S, Fowler WL, O’Laughlin IA, Meltzer HY. 5-HT (2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: a possible mechanism of atypical antipsychotic-induced cortical dopamine release. J Neurochem 2001; 76:1521-1531.
-
(2001)
J Neurochem
, vol.76
, pp. 1521-1531
-
-
Ichikawa, J.1
Ishii, H.2
Bonaccorso, S.3
Fowler, W.L.4
O’Laughlin, I.A.5
Meltzer, H.Y.6
-
65
-
-
0036398481
-
Antischizophrenic activity independent of dopamine D2 blockade
-
Kalkman HO. Antischizophrenic activity independent of dopamine D2 blockade. Expert Opin Ther Targets 2002; 6:571-582.
-
(2002)
Expert Opin Ther Targets
, vol.6
, pp. 571-582
-
-
Kalkman, H.O.1
-
66
-
-
0034045895
-
Indirect modulation of dopamine D2 receptors as potential pharmacotherapy for schizophrenia: II. Glutamate antagonists
-
Carfagno ML, Hoskins LA, Pinto ME, Yeh JC, Raffa RB. Indirect modulation of dopamine D2 receptors as potential pharmacotherapy for schizophrenia: II. Glutamate antagonists. Ann Pharmacother 2000; 34:788-797.
-
(2000)
Ann Pharmacother
, vol.34
, pp. 788-797
-
-
Carfagno, M.L.1
Hoskins, L.A.2
Pinto, M.E.3
Yeh, J.C.4
Raffa, R.B.5
-
67
-
-
0032526981
-
Dopamine neurons make glutamatergic synapses in vitro
-
Sulzer D, Joyce MP, Lin L, Geldwert D, Haber SN, Hattori T, Rayport S. Dopamine neurons make glutamatergic synapses in vitro. J Neurosci 1998 18:4588-4602.
-
(1998)
J Neurosci
, vol.18
, pp. 4588-4602
-
-
Sulzer, D.1
Joyce, M.P.2
Lin, L.3
Geldwert, D.4
Haber, S.N.5
Hattori, T.6
Rayport, S.7
-
68
-
-
0030905711
-
Familial and developmental abnormalities of front lobe function and neurochemistry in schizophrenia
-
Deakin FW, Simpson MD, Slater P, Hellewell JS. Familial and developmental abnormalities of front lobe function and neurochemistry in schizophrenia. J Psychopharmacol 1997; 11:133-142.
-
(1997)
J Psychopharmacol
, vol.11
, pp. 133-142
-
-
Deakin, F.W.1
Simpson, M.D.2
Slater, P.3
Hellewell, J.S.4
-
69
-
-
0036667177
-
Glycine modulators in schizophrenia
-
Javitt DC. Glycine modulators in schizophrenia. Curr Opin Investig Drugs 2002; 3:1067-1072.
-
(2002)
Curr Opin Investig Drugs
, vol.3
, pp. 1067-1072
-
-
Javitt, D.C.1
-
70
-
-
0041542278
-
Glycine transport inhibitors as potential antipsychotic drugs
-
Vandenberg RJ, Aubrey KR. Glycine transport inhibitors as potential antipsychotic drugs. Expert Opin Ther Targets 2001; 5:507-518.
-
(2001)
Expert Opin Ther Targets
, vol.5
, pp. 507-518
-
-
Vandenberg, R.J.1
Aubrey, K.R.2
-
71
-
-
0028172045
-
Allelic variation in the D4 dopamine receptor (DRD4) gene does not predict response to clozapine
-
Rao PA, Pickar D, Gejman PV, Ram A, Gershon ES, Gelernter J. Allelic variation in the D4 dopamine receptor (DRD4) gene does not predict response to clozapine. Arch Gen Psychiatry 1994; 51:912-917.
-
(1994)
Arch Gen Psychiatry
, vol.51
, pp. 912-917
-
-
Rao, P.A.1
Pickar, D.2
Gejman, P.V.3
Ram, A.4
Gershon, E.S.5
Gelernter, J.6
-
72
-
-
0031595105
-
Dopamine D2 and D4 receptor ligands: Relation to antipsychotic action
-
Wilson JM, Sanyal S, Van Tol HH. Dopamine D2 and D4 receptor ligands: relation to antipsychotic action. Eur J Pharmacol 1998; 351:273-286.
-
(1998)
Eur J Pharmacol
, vol.351
, pp. 273-286
-
-
Wilson, J.M.1
Sanyal, S.2
Van Tol, H.H.3
-
73
-
-
0018857834
-
Neurotensin: Perchance an endogenous neuroleptic?
-
Nemeroff CB. Neurotensin: perchance an endogenous neuroleptic? Biol Psychiatry 1980; 15:283-302.
-
(1980)
Biol Psychiatry
, vol.15
, pp. 283-302
-
-
Nemeroff, C.B.1
-
74
-
-
0032783157
-
Does neurotensin mediate the effects of antipsychotic drugs?
-
Kinkead B, Binder EB, Nemeroff CB. Does neurotensin mediate the effects of antipsychotic drugs? Biol Psychiatry 1999; 46:340-351.
-
(1999)
Biol Psychiatry
, vol.46
, pp. 340-351
-
-
Kinkead, B.1
Binder, E.B.2
Nemeroff, C.B.3
-
75
-
-
0028213047
-
CSF concentrations of neurotensin in schizophrenia: An investigation of clinical and biochemical correlates
-
Breslin NA, Suddath RL, Bissette G, Nemeroff CB, Lowrimore P, Weinberger DR. CSF concentrations of neurotensin in schizophrenia: an investigation of clinical and biochemical correlates. Schizophr Res 1994; 12:35-41.
-
(1994)
Schizophr Res
, vol.12
, pp. 35-41
-
-
Breslin, N.A.1
Suddath, R.L.2
Bissette, G.3
Nemeroff, C.B.4
Lowrimore, P.5
Weinberger, D.R.6
-
76
-
-
0035668473
-
The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs
-
Binder EB, Kinkead B, Owens MJ, Nemeroff CB. The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs. Biol Psychiatry 2001; 50:856-872.
-
(2001)
Biol Psychiatry
, vol.50
, pp. 856-872
-
-
Binder, E.B.1
Kinkead, B.2
Owens, M.J.3
Nemeroff, C.B.4
-
77
-
-
0036467316
-
Neurotensin: An endogenous antipsychotic?
-
Kinkead B, Nemeroff CB. Neurotensin: an endogenous antipsychotic? Curr Opin Pharmacol 2002; 2:99-103.
-
(2002)
Curr Opin Pharmacol
, vol.2
, pp. 99-103
-
-
Kinkead, B.1
Nemeroff, C.B.2
|