3,4-Methylenedioxymethamphetamine induces a hyperthermic and hypermetabolic crisis in pigs with and without a genetic disposition for malignant hyperthermia

European Journal of Anaesthesiology

Volumn 30, Issue 1, 2013, Pages 29-37

  Schütte, Jan K ^a   Schäfer, Ute ^a,b   Becker, Sandra ^a   Oldewurtel, Christiane ^a   Starosse, Alexander ^a   Singler, Peter ^c   Richard, Annette ^a   Wappler, Frank ^a   Gerbershagen, Mark U ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

3,4 methylenedioxymethamphetamine; Dantrolene sodium; Ecstasy; Malignant hyperthermia; Mitochondrial proteins; N methyl 3,4 methylenedioxyamphetamine; Uncoupling protein 3

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; DANTROLENE; FATTY ACID; NORADRENALIN; THYROID HORMONE; UNCOUPLING PROTEIN 3;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; BLOOD CARBON DIOXIDE TENSION; BLOOD PH; BODY TEMPERATURE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EFFICACY; DRUG FORMULATION; DRUG POTENCY; DRUG SAFETY; DRUG SOLUBILITY; FATTY ACID BLOOD LEVEL; GENETIC PREDISPOSITION; HYPERCAPNIA; HYPERMETABOLISM; INJECTION; LABORATORY TEST; MALIGNANT HYPERTHERMIA; MITOCHONDRION; NONHUMAN; NORADRENALIN BLOOD LEVEL; SUSPENSION; SWINE; THYROID HORMONE BLOOD LEVEL; UNIVERSITY HOSPITAL;

ACIDOSIS; ANIMALS; DANTROLENE; FATTY ACIDS, NONESTERIFIED; FEVER; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEMODYNAMICS; HOMOZYGOTE; HYDROGEN-ION CONCENTRATION; ION CHANNELS; MALIGNANT HYPERTHERMIA; MITOCHONDRIAL PROTEINS; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; NOREPINEPHRINE; SWINE; TIME FACTORS;

EID: 84872280294     PISSN: 02650215     EISSN: 13652346     Source Type: Journal    
DOI: 10.1097/EJA.0b013e32835a1127     Document Type: Article

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