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Volumn 160, Issue 2, 2013, Pages 153-170

Diagnosis and treatment of factor VIII and IX inhibitors in congenital haemophilia: (4th edition)

Author keywords

Bypassing agents; Factor VIII IX; Haemophilia; Haemostasis; Immune tolerance induction; Inhibitor

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 CONCENTRATE; BLOOD CLOTTING FACTOR 8 INHIBITOR; BLOOD CLOTTING FACTOR 9; BLOOD CLOTTING FACTOR 9 CONCENTRATE; BLOOD CLOTTING FACTOR 9 INHIBITOR; BLOOD CLOTTING INHIBITOR; DESMOPRESSIN; DEXAMETHASONE; HEMOSTATIC AGENT; IMMUNOGLOBULIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RECOMBINANT BLOOD CLOTTING FACTOR 7A; RECOMBINANT BLOOD CLOTTING FACTOR 8; RECOMBINANT BLOOD CLOTTING FACTOR 9; RITUXIMAB; STEROID; TRANEXAMIC ACID; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

EID: 84872264793     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.12091     Document Type: Note
Times cited : (186)

References (132)
  • 1
    • 13244262642 scopus 로고    scopus 로고
    • Comparative thrombotic event incidence after infusion of recombinant factor VIIa versus factor VIII inhibitor bypass activity
    • Aledort, L.M. (2004) Comparative thrombotic event incidence after infusion of recombinant factor VIIa versus factor VIII inhibitor bypass activity. Journal of Thrombosis and Haemostasis, 2, 1700-1708.
    • (2004) Journal of Thrombosis and Haemostasis , vol.2 , pp. 1700-1708
    • Aledort, L.M.1
  • 2
    • 80055114308 scopus 로고    scopus 로고
    • Can B-domain deletion alter the immunogenicity of recombinant factor VIII? A meta-analysis of prospective clinical studies
    • Aledort, L.M., Navickis, R.J. & Wilkes, M.M. (2011a) Can B-domain deletion alter the immunogenicity of recombinant factor VIII? A meta-analysis of prospective clinical studies. Journal of Thrombosis and Haemostasis, 9, 2180-2192.
    • (2011) Journal of Thrombosis and Haemostasis , vol.9 , pp. 2180-2192
    • Aledort, L.M.1    Navickis, R.J.2    Wilkes, M.M.3
  • 3
    • 80055102357 scopus 로고    scopus 로고
    • Best evidence on B-domain deletion and the immunogenicity of recombinant factor VIII
    • Aledort, L.M., Navickis, R.J. & Wilkes, M.M. (2011b) Best evidence on B-domain deletion and the immunogenicity of recombinant factor VIII. Journal of Thrombosis and Haemostasis, 9, 2325-2327.
    • (2011) Journal of Thrombosis and Haemostasis , vol.9 , pp. 2325-2327
    • Aledort, L.M.1    Navickis, R.J.2    Wilkes, M.M.3
  • 4
    • 37849045281 scopus 로고    scopus 로고
    • Rituximab and desensitization for a patient with severe factor IX deficiency, inhibitors, and history of anaphylaxis
    • Alexander, S., Hopewell, S., Hunter, S. & Chouksey, A. (2008) Rituximab and desensitization for a patient with severe factor IX deficiency, inhibitors, and history of anaphylaxis. Journal of Pediatric Hematology/oncology, 30, 93-95.
    • (2008) Journal of Pediatric Hematology/oncology , vol.30 , pp. 93-95
    • Alexander, S.1    Hopewell, S.2    Hunter, S.3    Chouksey, A.4
  • 5
    • 6644227418 scopus 로고    scopus 로고
    • The Malmö International Brother Study (MIBS): further support for genetic predisposition to inhibitor development in hemophilia patients
    • MIBS Study Group
    • Astermark, J., Berntorp, E., White, G.C. & Kroner, B.L.; MIBS Study Group. (2001) The Malmö International Brother Study (MIBS): further support for genetic predisposition to inhibitor development in hemophilia patients. Haemophilia, 7, 267-272.
    • (2001) Haemophilia , vol.7 , pp. 267-272
    • Astermark, J.1    Berntorp, E.2    White, G.C.3    Kroner, B.L.4
  • 6
    • 33846185403 scopus 로고    scopus 로고
    • A randomized comparison of bypassing agents in hemophilia complicated by an inhibitor: the FEIBA NovoSeven Comparative (FENOC) study
    • Astermark, J., Donfield, S.M., DiMichele, D.M., Gringeri, A., Gilbert, S.A., Waters, J. & Berntrop, E. (2007) A randomized comparison of bypassing agents in hemophilia complicated by an inhibitor: the FEIBA NovoSeven Comparative (FENOC) study. Blood, 109, 546-551.
    • (2007) Blood , vol.109 , pp. 546-551
    • Astermark, J.1    Donfield, S.M.2    DiMichele, D.M.3    Gringeri, A.4    Gilbert, S.A.5    Waters, J.6    Berntrop, E.7
  • 7
    • 84355162170 scopus 로고    scopus 로고
    • Early prophylaxis/FVIII tolerization regimen that avoids immunological danger signals is still effective in minimizing FVIII inhibitor developments in previously untreated patients-long-term follow-up and continuing experience
    • Auerswald, G., Bidlingmaier, C. & Kurnik, K. (2012) Early prophylaxis/FVIII tolerization regimen that avoids immunological danger signals is still effective in minimizing FVIII inhibitor developments in previously untreated patients-long-term follow-up and continuing experience. Haemophilia, 18, e18-e20.
    • (2012) Haemophilia , vol.18
    • Auerswald, G.1    Bidlingmaier, C.2    Kurnik, K.3
  • 8
    • 6744247123 scopus 로고    scopus 로고
    • Induction of immune tolerance with recombinant factor VIII in haemophilia A patients with inhibitors
    • Batlle, J., Lopez, M.F. & Brackmann, H.H. (1999) Induction of immune tolerance with recombinant factor VIII in haemophilia A patients with inhibitors. Haemophilia, 5, 431-435.
    • (1999) Haemophilia , vol.5 , pp. 431-435
    • Batlle, J.1    Lopez, M.F.2    Brackmann, H.H.3
  • 9
    • 84863538387 scopus 로고    scopus 로고
    • Management of bleeding in acquired hemophilia A (AHA): results from the European Acquired Hemophilia (EACH2) Registry
    • on behalf of the EACH2 registry contributors.
    • Baudo, F., Collins, P., Huth-Kuehne, A., Lévesque, H., Marco, P., Nemes, L., Pellegrini, F., Tengborn, L. & Knoebl, P.; on behalf of the EACH2 registry contributors. (2012) Management of bleeding in acquired hemophilia A (AHA): results from the European Acquired Hemophilia (EACH2) Registry. Blood, 120, 39-46.
    • (2012) Blood , vol.120 , pp. 39-46
    • Baudo, F.1    Collins, P.2    Huth-Kuehne, A.3    Lévesque, H.4    Marco, P.5    Nemes, L.6    Pellegrini, F.7    Tengborn, L.8    Knoebl, P.9
  • 10
    • 63049090494 scopus 로고    scopus 로고
    • Differential response to bypassing agents complicates treatment in patients with haemophilia and inhibitors
    • Berntorp, E. (2009) Differential response to bypassing agents complicates treatment in patients with haemophilia and inhibitors. Haemophilia, 15, 3-10.
    • (2009) Haemophilia , vol.15 , pp. 3-10
    • Berntorp, E.1
  • 11
    • 79951860657 scopus 로고    scopus 로고
    • Importance of rapid bleeding control in haemophilia complicated by inhibitors
    • Berntrop, E. (2011) Importance of rapid bleeding control in haemophilia complicated by inhibitors. Haemophilia, 17, 11-16.
    • (2011) Haemophilia , vol.17 , pp. 11-16
    • Berntrop, E.1
  • 12
    • 79951916913 scopus 로고    scopus 로고
    • Identifying non-responsive bleeding episodes in patients with haemophilia and inhibitors: a consensus definition
    • Berntrop, E., Collins, P., D'Oiron, R., Ewing, N., Gringeri, A., Negrier, C. & Young, G. (2011) Identifying non-responsive bleeding episodes in patients with haemophilia and inhibitors: a consensus definition. Haemophilia, 17, e202-e210.
    • (2011) Haemophilia , vol.17
    • Berntrop, E.1    Collins, P.2    D'Oiron, R.3    Ewing, N.4    Gringeri, A.5    Negrier, C.6    Young, G.7
  • 13
    • 66749168406 scopus 로고    scopus 로고
    • ITI with high-dose FIX and combined immunosuppressive therapy in a patient with severe haemophilia B and inhibitor
    • Beutel, K., Hauch, H., Rischewski, J., Kordes, U., Schneppenheim, J. & Schneppenheim, R. (2009) ITI with high-dose FIX and combined immunosuppressive therapy in a patient with severe haemophilia B and inhibitor. Hamostaseologie, 29, 155-157.
    • (2009) Hamostaseologie , vol.29 , pp. 155-157
    • Beutel, K.1    Hauch, H.2    Rischewski, J.3    Kordes, U.4    Schneppenheim, J.5    Schneppenheim, R.6
  • 14
    • 79951789201 scopus 로고    scopus 로고
    • A commentary on the differences in pharmacokinetics between recombinant and plasma-derived factor IX and their implications for dosing
    • Björkman, S. (2011) A commentary on the differences in pharmacokinetics between recombinant and plasma-derived factor IX and their implications for dosing. Haemophilia, 17, 179-184.
    • (2011) Haemophilia , vol.17 , pp. 179-184
    • Björkman, S.1
  • 15
    • 33845730827 scopus 로고    scopus 로고
    • In vivo recovery of factor VIII and factor IX: intra- and interindividual variance in a clinical setting
    • Björkman, S., Folkesson, A. & Berntorp, E. (2007) In vivo recovery of factor VIII and factor IX: intra- and interindividual variance in a clinical setting. Haemophilia, 13, 2-8.
    • (2007) Haemophilia , vol.13 , pp. 2-8
    • Björkman, S.1    Folkesson, A.2    Berntorp, E.3
  • 16
    • 77952712296 scopus 로고    scopus 로고
    • Comparative pharmacokinetics of plasma- and albumin-free recombinant factor VIII in children and adults: the influence of blood sampling schedule on observed age-related differences and implications for dose tailoring
    • Advate Clinical Program Group
    • Björkman, S., Blanchette, V.S., Fischer, K., Oh, M., Spotts, G., Schroth, P., Fritsch, S., Patrone, L., Ewenstein, B.M.; Advate Clinical Program Group. & Collins, P.W. (2010) Comparative pharmacokinetics of plasma- and albumin-free recombinant factor VIII in children and adults: the influence of blood sampling schedule on observed age-related differences and implications for dose tailoring. Journal of Thrombosis and Haemostasis, 8, 730-736.
    • (2010) Journal of Thrombosis and Haemostasis , vol.8 , pp. 730-736
    • Björkman, S.1    Blanchette, V.S.2    Fischer, K.3    Oh, M.4    Spotts, G.5    Schroth, P.6    Fritsch, S.7    Patrone, L.8    Ewenstein, B.M.9    Collins, P.W.10
  • 19
    • 47649119586 scopus 로고    scopus 로고
    • Factor VIII genotype and inhibitor development in patients with haemophilia A: highest risk in patients with splice site mutations
    • Boekhorst, J., Lari, G.R., D'Oiron, R., Costa, J.M., Nováková, I.R., Ala, F.A., Lavergne, J.M. & van Heerde, W.L. (2008) Factor VIII genotype and inhibitor development in patients with haemophilia A: highest risk in patients with splice site mutations. Haemophilia, 14, 729-735.
    • (2008) Haemophilia , vol.14 , pp. 729-735
    • Boekhorst, J.1    Lari, G.R.2    D'Oiron, R.3    Costa, J.M.4    Nováková, I.R.5    Ala, F.A.6    Lavergne, J.M.7    van Heerde, W.L.8
  • 20
    • 0030056318 scopus 로고    scopus 로고
    • Immune tolerance for the treatment of factor VIII inhibitors - twenty years of the Bonn protocol
    • Brackmann, H.H., Oldenburg, J. & Swaab, R. (1996) Immune tolerance for the treatment of factor VIII inhibitors - twenty years of the Bonn protocol. Vox Sanguinis, 70, 30-35.
    • (1996) Vox Sanguinis , vol.70 , pp. 30-35
    • Brackmann, H.H.1    Oldenburg, J.2    Swaab, R.3
  • 21
    • 0028266130 scopus 로고
    • A multicenter study of recombinant factor VIII (recombinate): safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A. The Recombinate Study Group
    • Bray, G.L., Gomperts, E.D., Courter, S., Gruppo, R., Gordon, E.M., Manco-Johnson, M., Shapiro, A., Scheibel, E., White, G. 3rd & Lee, M. (1994) A multicenter study of recombinant factor VIII (recombinate): safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A. The Recombinate Study Group. Blood, 83, 2428-2435.
    • (1994) Blood , vol.83 , pp. 2428-2435
    • Bray, G.L.1    Gomperts, E.D.2    Courter, S.3    Gruppo, R.4    Gordon, E.M.5    Manco-Johnson, M.6    Shapiro, A.7    Scheibel, E.8    White, G.9    Lee, M.10
  • 22
    • 33645981947 scopus 로고    scopus 로고
    • Rituximab for congenital haemophiliacs with inhibitors: a Canadian experience
    • Inhibitor Subcommittee of Association of Hemophilia Clinic Directors of Canada.
    • Carcao, M., St Louis, J., Poon, M.C., Grunebaum, E., Lacroix, S., Stain, A.M., Blanchette, V.S. & Rivard, G.E.; Inhibitor Subcommittee of Association of Hemophilia Clinic Directors of Canada. (2006) Rituximab for congenital haemophiliacs with inhibitors: a Canadian experience. Haemophilia, 12, 7-18.
    • (2006) Haemophilia , vol.12 , pp. 7-18
    • Carcao, M.1    St Louis, J.2    Poon, M.C.3    Grunebaum, E.4    Lacroix, S.5    Stain, A.M.6    Blanchette, V.S.7    Rivard, G.E.8
  • 24
    • 69949092766 scopus 로고    scopus 로고
    • Inhibitors in factor IX deficiency a report of the ISTH-SSC international FIX inhibitor registry (1997-2006)
    • Chitlur, M., Warrier, I., Rajpurkar, M. & Lusher, J.M. (2009) Inhibitors in factor IX deficiency a report of the ISTH-SSC international FIX inhibitor registry (1997-2006). Haemophilia, 5, 1027-1031.
    • (2009) Haemophilia , vol.5 , pp. 1027-1031
    • Chitlur, M.1    Warrier, I.2    Rajpurkar, M.3    Lusher, J.M.4
  • 28
    • 33845771297 scopus 로고    scopus 로고
    • Cyclosporin A can achieve immune tolerance in a patient with severe haemophilia B and refractory inhibitors
    • Cross, D.C. & Van Den Berg, H.M. (2007) Cyclosporin A can achieve immune tolerance in a patient with severe haemophilia B and refractory inhibitors. Haemophilia, 13, 111-114.
    • (2007) Haemophilia , vol.13 , pp. 111-114
    • Cross, D.C.1    Van Den Berg, H.M.2
  • 29
    • 34248572204 scopus 로고    scopus 로고
    • Achievement of immune tolerance in a patient with haemophilia B and inhibitory antibodies, complicated by an anaphylactoid reaction
    • Curry, N.S., Misbah, S.A., Giangrande, P.L. & Keeling, D.M. (2007) Achievement of immune tolerance in a patient with haemophilia B and inhibitory antibodies, complicated by an anaphylactoid reaction. Haemophilia, 13, 328-330.
    • (2007) Haemophilia , vol.13 , pp. 328-330
    • Curry, N.S.1    Misbah, S.A.2    Giangrande, P.L.3    Keeling, D.M.4
  • 31
    • 44349188657 scopus 로고    scopus 로고
    • New advances in the therapeutic and laboratory management of patients with haemophilia and inhibitors
    • Dargaud, Y., Lambert, T. & Trossaert, M. (2008) New advances in the therapeutic and laboratory management of patients with haemophilia and inhibitors. Haemophilia, 14(Suppl. 4), 20-27.
    • (2008) Haemophilia , vol.14 , Issue.SUPPL. 4 , pp. 20-27
    • Dargaud, Y.1    Lambert, T.2    Trossaert, M.3
  • 32
    • 78650492660 scopus 로고    scopus 로고
    • Prospective assessment of thrombin generation test for dose monitoring of bypassing therapy in hemophilia patients with inhibitors undergoing elective surgery
    • Dargaud, Y., Lienhart, A. & Negrier, C. (2010) Prospective assessment of thrombin generation test for dose monitoring of bypassing therapy in hemophilia patients with inhibitors undergoing elective surgery. Blood, 116, 5734-5737.
    • (2010) Blood , vol.116 , pp. 5734-5737
    • Dargaud, Y.1    Lienhart, A.2    Negrier, C.3
  • 33
    • 0038148528 scopus 로고    scopus 로고
    • Immune tolerance therapy dose as an outcome predictor
    • DiMichele, D.M. (2003) Immune tolerance therapy dose as an outcome predictor. Haemophilia, 9, 382-386.
    • (2003) Haemophilia , vol.9 , pp. 382-386
    • DiMichele, D.M.1
  • 34
    • 34447128837 scopus 로고    scopus 로고
    • Inhibitor development in haemophilia B: an orphan disease in need of attention
    • DiMichele, D. (2007) Inhibitor development in haemophilia B: an orphan disease in need of attention. British Journal of Haematology, 138, 305-315.
    • (2007) British Journal of Haematology , vol.138 , pp. 305-315
    • DiMichele, D.1
  • 35
    • 63049130236 scopus 로고    scopus 로고
    • The North American Immune Tolerance Registry: contributions to the thirty-year experience with immune tolerance therapy
    • DiMichele, D. (2009) The North American Immune Tolerance Registry: contributions to the thirty-year experience with immune tolerance therapy. Haemophilia, 15, 320-328.
    • (2009) Haemophilia , vol.15 , pp. 320-328
    • DiMichele, D.1
  • 36
    • 0036147943 scopus 로고    scopus 로고
    • The North American Immune Tolerance registry: practices, outcomes, outcome predictors
    • the North American Immune Tolerance Study Group
    • DiMichele, D.M. & Kroner, B.; the North American Immune Tolerance Study Group. (2002) The North American Immune Tolerance registry: practices, outcomes, outcome predictors. Thrombosis and Haemostasis, 87, 52-57.
    • (2002) Thrombosis and Haemostasis , vol.87 , pp. 52-57
    • DiMichele, D.M.1    Kroner, B.2
  • 37
    • 33750342991 scopus 로고    scopus 로고
    • A retrospective postlicensure survey of FEIBA efficacy and safety
    • DiMichele, D. & Négrier, C. (2006) A retrospective postlicensure survey of FEIBA efficacy and safety. Haemophilia, 12, 352-362.
    • (2006) Haemophilia , vol.12 , pp. 352-362
    • DiMichele, D.1    Négrier, C.2
  • 42
    • 0019943712 scopus 로고
    • In vitro detection of mild inhibitors to factor VIII in hemophilia
    • Ewing, N.P. & Kasper, C.K. (1982) In vitro detection of mild inhibitors to factor VIII in hemophilia. American Journal of Clinical Pathology, 77, 749-752.
    • (1982) American Journal of Clinical Pathology , vol.77 , pp. 749-752
    • Ewing, N.P.1    Kasper, C.K.2
  • 43
    • 33645980622 scopus 로고    scopus 로고
    • Rituximab for adolescents with haemophilia and high titre inhibitors
    • Fox, R.A., Neufeld, E.J. & Bennett, C.M. (2006) Rituximab for adolescents with haemophilia and high titre inhibitors. Haemophilia, 12, 218-222.
    • (2006) Haemophilia , vol.12 , pp. 218-222
    • Fox, R.A.1    Neufeld, E.J.2    Bennett, C.M.3
  • 44
    • 78149492011 scopus 로고    scopus 로고
    • Von Willebrand factor-containing factor VIII concentrates and inhibitors in haemophilia A. A critical literature review
    • Franchini, M. & Lippi, G. (2010) Von Willebrand factor-containing factor VIII concentrates and inhibitors in haemophilia A. A critical literature review. Thrombosis and Haemostasis, 104, 931-940.
    • (2010) Thrombosis and Haemostasis , vol.104 , pp. 931-940
    • Franchini, M.1    Lippi, G.2
  • 46
    • 63349099323 scopus 로고    scopus 로고
    • Consensus protocol for the use of recombinant activated factor VII [eptacog alfa (activated); NovoSeven] in elective orthopaedic surgery in haemophilic patients with inhibitors
    • Giangrande, P.L., Wilde, J.T., Madan, B., Ludlam, C.A., Tuddenham, E.G., Goddard, N.J., Dolan, G. & Ingerslev, J. (2009) Consensus protocol for the use of recombinant activated factor VII [eptacog alfa (activated); NovoSeven] in elective orthopaedic surgery in haemophilic patients with inhibitors. Haemophilia, 15, 501-508.
    • (2009) Haemophilia , vol.15 , pp. 501-508
    • Giangrande, P.L.1    Wilde, J.T.2    Madan, B.3    Ludlam, C.A.4    Tuddenham, E.G.5    Goddard, N.J.6    Dolan, G.7    Ingerslev, J.8
  • 47
    • 34249690732 scopus 로고    scopus 로고
    • Treatment-related risk factors of inhibitor development in previously untreated patients with hemophilia A: the CANAL cohort study
    • Gouw, S.C., van der Bom, J.G. & Marijke van Den Berg, H. (2007a) Treatment-related risk factors of inhibitor development in previously untreated patients with hemophilia A: the CANAL cohort study. Blood, 109, 4648-4654.
    • (2007) Blood , vol.109 , pp. 4648-4654
    • Gouw, S.C.1    van der Bom, J.G.2    Marijke van Den Berg, H.3
  • 48
    • 34250708408 scopus 로고    scopus 로고
    • Treatment characteristics and the risk of inhibitor development: a multicenter cohort study among previously untreated patients with severe hemophilia A
    • Gouw, S.C., van Den Berg, H.M., le Cessie, S. & van der Bom, J.G. (2007b) Treatment characteristics and the risk of inhibitor development: a multicenter cohort study among previously untreated patients with severe hemophilia A. Journal of Thrombosis and Haemostasis, 5, 1383-1390.
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , pp. 1383-1390
    • Gouw, S.C.1    van Den Berg, H.M.2    le Cessie, S.3    van der Bom, J.G.4
  • 51
    • 37149006720 scopus 로고    scopus 로고
    • VWF/FVIII concentrates in high-risk immunotolerance: the RESIST Study
    • Gringeri, A. (2007) VWF/FVIII concentrates in high-risk immunotolerance: the RESIST Study. Haemophilia, 13(Suppl. 5), 73-77.
    • (2007) Haemophilia , vol.13 , Issue.SUPPL. 5 , pp. 73-77
    • Gringeri, A.1
  • 52
    • 27744516149 scopus 로고    scopus 로고
    • Italian guidelines for the diagnosis and treatment of patients with haemophilia and inhibitors
    • Gringeri, A. & Mannucci, P.M. (2005) Italian guidelines for the diagnosis and treatment of patients with haemophilia and inhibitors. Haemophilia, 11, 611-619.
    • (2005) Haemophilia , vol.11 , pp. 611-619
    • Gringeri, A.1    Mannucci, P.M.2
  • 53
    • 34447287337 scopus 로고    scopus 로고
    • Immune tolerance induction with a high purity von willebrand factor VIII complex concentrate in haemophilia A patients with inhibitors at high risk of poor response
    • RITS-FITNHES Study Group
    • Gringeri, A., Musso, R., Mazzucconi, M.G., Piseddu, G., Schiavoni, M., Pignoloni, P. & Mannucci, P.M.; RITS-FITNHES Study Group. (2007) Immune tolerance induction with a high purity von willebrand factor VIII complex concentrate in haemophilia A patients with inhibitors at high risk of poor response. Haemophilia, 13, 373-379.
    • (2007) Haemophilia , vol.13 , pp. 373-379
    • Gringeri, A.1    Musso, R.2    Mazzucconi, M.G.3    Piseddu, G.4    Schiavoni, M.5    Pignoloni, P.6    Mannucci, P.M.7
  • 54
    • 79959509081 scopus 로고    scopus 로고
    • Sequential combined bypassing therapy is safe and effective in the treatment of unresponsive bleeding in adults and children with haemophilia and inhibitors
    • European Haemophilia Treatment Standardisation Board (EHTSB).
    • Gringeri, A., Fischer, K., Karafoulidou, A., Klamroth, R., LópezFernández, M.F. & Mancuso, E.; European Haemophilia Treatment Standardisation Board (EHTSB). (2011) Sequential combined bypassing therapy is safe and effective in the treatment of unresponsive bleeding in adults and children with haemophilia and inhibitors. Haemophilia, 17, 630-635.
    • (2011) Haemophilia , vol.17 , pp. 630-635
    • Gringeri, A.1    Fischer, K.2    Karafoulidou, A.3    Klamroth, R.4    LópezFernández, M.F.5    Mancuso, E.6
  • 55
    • 84856866914 scopus 로고    scopus 로고
    • The principal results of the International Immune Tolerance Study: a randomized dose comparison
    • for the International Immune Tolerance Study.
    • Hay, C.R. & DiMichele, D.M.; for the International Immune Tolerance Study. (2012) The principal results of the International Immune Tolerance Study: a randomized dose comparison. Blood, 119, 1335-1344.
    • (2012) Blood , vol.119 , pp. 1335-1344
    • Hay, C.R.1    DiMichele, D.M.2
  • 57
    • 0033768130 scopus 로고    scopus 로고
    • The diagnosis and management of factor VIII and IX inhibitors: a guideline from the UK Haemophilia Centre Doctors' Organization (UKHCDO)
    • Hay, C.R., Baglin, T.P., Collins, P.W., Hill, F.G. & Keeling, D.M. (2000) The diagnosis and management of factor VIII and IX inhibitors: a guideline from the UK Haemophilia Centre Doctors' Organization (UKHCDO). British Journal of Haematology, 111, 78-90.
    • (2000) British Journal of Haematology , vol.111 , pp. 78-90
    • Hay, C.R.1    Baglin, T.P.2    Collins, P.W.3    Hill, F.G.4    Keeling, D.M.5
  • 58
    • 33646686129 scopus 로고    scopus 로고
    • The diagnosis and management of factor VIII and IX inhibitors: a guideline from the United Kingdom Haemophilia Centre Doctors Organisation
    • Hay, C.R., Brown, S., Collins, P.W., Keeling, D.M. & Liesner, R. (2006) The diagnosis and management of factor VIII and IX inhibitors: a guideline from the United Kingdom Haemophilia Centre Doctors Organisation. British Journal of Haematology, 133, 591-605.
    • (2006) British Journal of Haematology , vol.133 , pp. 591-605
    • Hay, C.R.1    Brown, S.2    Collins, P.W.3    Keeling, D.M.4    Liesner, R.5
  • 59
    • 79959486802 scopus 로고    scopus 로고
    • Incidence of factor VIII inhibitors throughout life in severe hemophilia A in the United Kingdom
    • United Kingdom Haemophilia Centre Doctors' Organisation (UKHCDO).
    • Hay, C.R., Palmer, B., Chalmers, E., Liesner, R., Maclean, R., Rangarajan, S., Williams, M. & Collins, P.W.; United Kingdom Haemophilia Centre Doctors' Organisation (UKHCDO). (2011) Incidence of factor VIII inhibitors throughout life in severe hemophilia A in the United Kingdom. Blood, 117, 6367-6370.
    • (2011) Blood , vol.117 , pp. 6367-6370
    • Hay, C.R.1    Palmer, B.2    Chalmers, E.3    Liesner, R.4    Maclean, R.5    Rangarajan, S.6    Williams, M.7    Collins, P.W.8
  • 60
    • 0038441421 scopus 로고    scopus 로고
    • Long-term FEIBA prophylaxis does not prevent progression of existing joint disease
    • Hilgartner, M.W., Makipernaa, A. & DiMichele, D.M. (2003) Long-term FEIBA prophylaxis does not prevent progression of existing joint disease. Haemophilia, 9, 261-268.
    • (2003) Haemophilia , vol.9 , pp. 261-268
    • Hilgartner, M.W.1    Makipernaa, A.2    DiMichele, D.M.3
  • 61
    • 84863222250 scopus 로고    scopus 로고
    • ®)) and tranexamic acid in patients with haemophilia A with inhibitors and in patients with acquired haemophilia A - a two-centre experience
    • ®)) and tranexamic acid in patients with haemophilia A with inhibitors and in patients with acquired haemophilia A - a two-centre experience. Haemophilia, 18, 544-549.
    • (2012) Haemophilia , vol.18 , pp. 544-549
    • Holmström, M.1    Tran, H.T.2    Holme, P.A.3
  • 62
    • 80053570793 scopus 로고    scopus 로고
    • Parallel use of by-passing agents in haemophilia with inhibitors: a critical review
    • Ingerslev, J. & Sørensen, B. (2011) Parallel use of by-passing agents in haemophilia with inhibitors: a critical review. British Journal of Haematology, 155, 256-262.
    • (2011) British Journal of Haematology , vol.155 , pp. 256-262
    • Ingerslev, J.1    Sørensen, B.2
  • 63
    • 77955947213 scopus 로고    scopus 로고
    • Recombinant factor VIIa concentrate versus plasma derived concentrates for the treatment of acute bleeding episodes in people with haemophilia and inhibitors
    • Art No.: CD, DOI:10.1002/14651858.CD004449, pub3.
    • Iorio, A., Matino, D., D'Amico, R. & Makris, M. (2010a) Recombinant factor VIIa concentrate versus plasma derived concentrates for the treatment of acute bleeding episodes in people with haemophilia and inhibitors. Cochrane Database of Systematic Reviews, Art No.: CD, DOI:10.1002/14651858.CD004449, pub3.
    • (2010) Cochrane Database of Systematic Reviews
    • Iorio, A.1    Matino, D.2    D'Amico, R.3    Makris, M.4
  • 65
  • 68
    • 33645750469 scopus 로고    scopus 로고
    • Home treatment of haemarthroses using a single dose regimen of recombinant activated factor VII in patients with haemophilia and inhibitors
    • Kavalki, K., Makris, M., Zulfikar, B., Erhardtsen, E., Abrams, Z.S. & Kenet, G. (2006) Home treatment of haemarthroses using a single dose regimen of recombinant activated factor VII in patients with haemophilia and inhibitors. Thrombosis and Haemostasis, 95, 600-605.
    • (2006) Thrombosis and Haemostasis , vol.95 , pp. 600-605
    • Kavalki, K.1    Makris, M.2    Zulfikar, B.3    Erhardtsen, E.4    Abrams, Z.S.5    Kenet, G.6
  • 69
    • 15944372558 scopus 로고    scopus 로고
    • A simple inhibitor screen is more sensitive than a Bethesda assay in monitoring for the development of inhibitors in haemophilia A and B
    • Keeling, D., Beavis, J. & Sukhu, K. (2005) A simple inhibitor screen is more sensitive than a Bethesda assay in monitoring for the development of inhibitors in haemophilia A and B. British Journal of Haematology, 128, 885.
    • (2005) British Journal of Haematology , vol.128 , pp. 885
    • Keeling, D.1    Beavis, J.2    Sukhu, K.3
  • 70
    • 59449097322 scopus 로고    scopus 로고
    • How we treat a hemophilia A patient with a factor VIII inhibitor
    • Kempton, C.L. & White, G.C. (2009) How we treat a hemophilia A patient with a factor VIII inhibitor. Blood, 113, 11-17.
    • (2009) Blood , vol.113 , pp. 11-17
    • Kempton, C.L.1    White, G.C.2
  • 73
  • 74
  • 77
    • 0002016387 scopus 로고    scopus 로고
    • Successful immunetolerance therapy of FVIII inhibitor in children after changing from high to intermediate purity FVIII concentrate
    • Kreuz, W., Mentzer, D., Auerswald, G., Becker, S. & Joseph-Steiner, J. (1996) Successful immunetolerance therapy of FVIII inhibitor in children after changing from high to intermediate purity FVIII concentrate. Haemophilia, 2(Suppl. 1), 19.
    • (1996) Haemophilia , vol.2 , Issue.SUPPL. 1 , pp. 19
    • Kreuz, W.1    Mentzer, D.2    Auerswald, G.3    Becker, S.4    Joseph-Steiner, J.5
  • 78
    • 79955114793 scopus 로고    scopus 로고
    • Efficacy and safety of FVIII inhibitor bypassing activity (FEIBA) for long-term prophylaxis in patients with high-responding inhibitors
    • abs 1140.
    • Kreuz, W., Escurich-Ettinghauser, C., Martinez, I., Mentzer, D., Figura, S. & Klarmann, D. (2000) Efficacy and safety of FVIII inhibitor bypassing activity (FEIBA) for long-term prophylaxis in patients with high-responding inhibitors. Blood, 96, 265a, abs 1140.
    • (2000) Blood , vol.96
    • Kreuz, W.1    Escurich-Ettinghauser, C.2    Martinez, I.3    Mentzer, D.4    Figura, S.5    Klarmann, D.6
  • 79
    • 0032882450 scopus 로고    scopus 로고
    • Comparison of the international immune tolerance registry and the North American Immune tolerance registry
    • Kroner, B.L. (1999) Comparison of the international immune tolerance registry and the North American Immune tolerance registry. Vox sanguinis, 77, 33-37.
    • (1999) Vox sanguinis , vol.77 , pp. 33-37
    • Kroner, B.L.1
  • 81
    • 84872267643 scopus 로고    scopus 로고
    • the Factor VIII/Factor IX Scientific and Standardization Committee of the International Society for Thrombosis and Haemostasis. () Scientific and Standardization Committee Communication: The design and analysis of pharmacokinetic studies of coagulation factors.
    • Lee, M., Morfini, M., Schulman, S. & Ingerslev, J.; the Factor VIII/Factor IX Scientific and Standardization Committee of the International Society for Thrombosis and Haemostasis. (2001) Scientific and Standardization Committee Communication: The design and analysis of pharmacokinetic studies of coagulation factors. http://www.isth.org/default/assets/File/fviiipharmaco.pdf
    • (2001)
    • Lee, M.1    Morfini, M.2    Schulman, S.3    Ingerslev, J.4
  • 82
    • 34248562674 scopus 로고    scopus 로고
    • Prophylactic treatment with activated prothrombin complex concentrate (FEIBA) reduces the frequency of bleeding episodes in paediatric patients with haemophilia A and inhibitors
    • Leissinger, C.A., Becton, D.L., Ewing, N.P. & Valentino, L.A. (2007) Prophylactic treatment with activated prothrombin complex concentrate (FEIBA) reduces the frequency of bleeding episodes in paediatric patients with haemophilia A and inhibitors. Haemophilia, 13, 249-255.
    • (2007) Haemophilia , vol.13 , pp. 249-255
    • Leissinger, C.A.1    Becton, D.L.2    Ewing, N.P.3    Valentino, L.A.4
  • 84
    • 0032875191 scopus 로고    scopus 로고
    • The German National Immune Tolerance Registry 1997 update
    • Lenk, H. (1999) The German National Immune Tolerance Registry 1997 update. Vox Sanguinis, 77(Suppl. 1), 28-30.
    • (1999) Vox Sanguinis , vol.77 , Issue.SUPPL. 1 , pp. 28-30
    • Lenk, H.1
  • 86
    • 0344406183 scopus 로고    scopus 로고
    • A prospective study of recombinant activated factor VII administered by continuous infusion to inhibitor patients undergoing elective major orthopaedic surgery: a pharmacokinetic and efficacy evaluation
    • Ludlam, C.A., Smith, M.P., Morfini, M., Gringeri, A., Santagostino, E. & Savidge, G.F. (2003) A prospective study of recombinant activated factor VII administered by continuous infusion to inhibitor patients undergoing elective major orthopaedic surgery: a pharmacokinetic and efficacy evaluation. British Journal of Haematology, 120, 808-813.
    • (2003) British Journal of Haematology , vol.120 , pp. 808-813
    • Ludlam, C.A.1    Smith, M.P.2    Morfini, M.3    Gringeri, A.4    Santagostino, E.5    Savidge, G.F.6
  • 87
    • 0027473752 scopus 로고
    • Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. Safety, efficacy, and development of inhibitors. Kogenate Previously Untreated Patient Study Group
    • Lusher, J.M., Arkin, S., Abildgaard, C.F. & Schwartz, R.S. (1993) Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. Safety, efficacy, and development of inhibitors. Kogenate Previously Untreated Patient Study Group. New England Journal of Medicine, 328, 453-459.
    • (1993) New England Journal of Medicine , vol.328 , pp. 453-459
    • Lusher, J.M.1    Arkin, S.2    Abildgaard, C.F.3    Schwartz, R.S.4
  • 88
    • 0037276262 scopus 로고    scopus 로고
    • The safety and efficacy of B-domain deleted recombinant factor VIII concentrate in patients with severe haemophilia A
    • ReFacto Phase 3 Study Group
    • Lusher, J.M., Lee, C.A., Kessler, C.M. & Bedrosian, C.L.; ReFacto Phase 3 Study Group. (2003) The safety and efficacy of B-domain deleted recombinant factor VIII concentrate in patients with severe haemophilia A. Haemophilia, 9, 38-49.
    • (2003) Haemophilia , vol.9 , pp. 38-49
    • Lusher, J.M.1    Lee, C.A.2    Kessler, C.M.3    Bedrosian, C.L.4
  • 90
    • 0028240520 scopus 로고
    • Immunetolerance in hemophilia. Principal results from the international registry
    • Mariani, G., Ghirardini, A. & Belloco, R. (1994) Immunetolerance in hemophilia. Principal results from the international registry. Thrombosis and Haemostasis, 72, 155-158.
    • (1994) Thrombosis and Haemostasis , vol.72 , pp. 155-158
    • Mariani, G.1    Ghirardini, A.2    Belloco, R.3
  • 91
    • 67649868161 scopus 로고    scopus 로고
    • Concomitant infusion of low doses of rFVIIa and FEIBA in haemophilia patients with inhibitors
    • Martinowitz, U., Livnat, T., Zivelin, A. & Kenet, G. (2009) Concomitant infusion of low doses of rFVIIa and FEIBA in haemophilia patients with inhibitors. Haemophilia, 15, 904-910.
    • (2009) Haemophilia , vol.15 , pp. 904-910
    • Martinowitz, U.1    Livnat, T.2    Zivelin, A.3    Kenet, G.4
  • 92
    • 2442472195 scopus 로고    scopus 로고
    • Rituximab in the treatment of alloimmune factor VIII and IX antibodies in two children with severe haemophilia
    • Mathias, M., Khair, K., Hann, I. & Liesner, R. (2004) Rituximab in the treatment of alloimmune factor VIII and IX antibodies in two children with severe haemophilia. British Journal of Haematology, 125, 366-368.
    • (2004) British Journal of Haematology , vol.125 , pp. 366-368
    • Mathias, M.1    Khair, K.2    Hann, I.3    Liesner, R.4
  • 94
    • 0029133532 scopus 로고
    • Low-dose immune tolerance induction in haemophilia A patients with inhibitors
    • Mauser-Bunschoten, E.P., Niewenhuis, H.K., Roosendaal, G. & van Den Berg, H.M. (1995) Low-dose immune tolerance induction in haemophilia A patients with inhibitors. Blood, 86, 983-988.
    • (1995) Blood , vol.86 , pp. 983-988
    • Mauser-Bunschoten, E.P.1    Niewenhuis, H.K.2    Roosendaal, G.3    van Den Berg, H.M.4
  • 95
    • 0023856830 scopus 로고
    • The natural history of factor VIII:C inhibitors in patients with hemophilia A: a national cooperative study. II. Observations on the initial development of factor VIII:C inhibitors
    • McMillan, C.W., Shapiro, S.S., Whitehurst, D., Hoyer, L.W., Rao, A.V. & Lazerson, J. (1988) The natural history of factor VIII:C inhibitors in patients with hemophilia A: a national cooperative study. II. Observations on the initial development of factor VIII:C inhibitors. Blood, 71, 344-348.
    • (1988) Blood , vol.71 , pp. 344-348
    • McMillan, C.W.1    Shapiro, S.S.2    Whitehurst, D.3    Hoyer, L.W.4    Rao, A.V.5    Lazerson, J.6
  • 96
    • 84861673289 scopus 로고    scopus 로고
    • Validation of Nijmegen-Bethesda assay modifications to allow inhibitor measurement during replacement therapy and facilitate inhibitor surveillance
    • Hemophilia Inhibitor Research Study Investigators.
    • Miller, C.H., Platt, S.J., Rice, A.S., Kelly, F. & Soucie, J.M.; Hemophilia Inhibitor Research Study Investigators. (2012) Validation of Nijmegen-Bethesda assay modifications to allow inhibitor measurement during replacement therapy and facilitate inhibitor surveillance. Journal of Thrombosis and Haemostasis, 10, 1055-1061.
    • (2012) Journal of Thrombosis and Haemostasis , vol.10 , pp. 1055-1061
    • Miller, C.H.1    Platt, S.J.2    Rice, A.S.3    Kelly, F.4    Soucie, J.M.5
  • 98
    • 77954856457 scopus 로고    scopus 로고
    • Recombinant activated actor VII safety and efficacy in the treatment of cranial haemorrhage in patients with congenital haemophilia with inhibitors: an analysis of the Haemophilia and Thrombosis Research Society Registry (2004-2008)
    • Nakar, C., Cooper, D.L. & DiMichele, D. (2010) Recombinant activated actor VII safety and efficacy in the treatment of cranial haemorrhage in patients with congenital haemophilia with inhibitors: an analysis of the Haemophilia and Thrombosis Research Society Registry (2004-2008). Haemophilia, 16, 625-631.
    • (2010) Haemophilia , vol.16 , pp. 625-631
    • Nakar, C.1    Cooper, D.L.2    DiMichele, D.3
  • 99
    • 40349100414 scopus 로고    scopus 로고
    • Recombinant activated factor VII for haemophilia patients with inhibitors undergoing orthopaedic surgery: a review of the literature
    • Obergfell, A., Auvinen, M.K. & Mathew, P. (2008) Recombinant activated factor VII for haemophilia patients with inhibitors undergoing orthopaedic surgery: a review of the literature. Haemophilia, 14, 233-241.
    • (2008) Haemophilia , vol.14 , pp. 233-241
    • Obergfell, A.1    Auvinen, M.K.2    Mathew, P.3
  • 100
    • 33751014075 scopus 로고    scopus 로고
    • Genetic risk factors for inhibitors to factors VIII and IX
    • Oldenburg, J. & Pavlova, A. (2006) Genetic risk factors for inhibitors to factors VIII and IX. Haemophilia, 12(Suppl. 6), 15-22.
    • (2006) Haemophilia , vol.12 , Issue.SUPPL. 6 , pp. 15-22
    • Oldenburg, J.1    Pavlova, A.2
  • 101
    • 35048845078 scopus 로고    scopus 로고
    • Haemostatic effect and safety of bolus and continuous infusion of recombinant factor VIIa are comparable in haemophilia patients with inhibitors undergoing major surgery. Results from an open-label, randomized, multicenter trial
    • NovoSeven in Surgery Study Investigators.
    • Pruthi, R.K., Mathew, P., Valentino, L.A., Sumner, M.J., Seremetis, S. & Hoots, W.K.; NovoSeven in Surgery Study Investigators. (2007) Haemostatic effect and safety of bolus and continuous infusion of recombinant factor VIIa are comparable in haemophilia patients with inhibitors undergoing major surgery. Results from an open-label, randomized, multicenter trial. Thrombosis and Haemostasis, 98, 710-712.
    • (2007) Thrombosis and Haemostasis , vol.98 , pp. 710-712
    • Pruthi, R.K.1    Mathew, P.2    Valentino, L.A.3    Sumner, M.J.4    Seremetis, S.5    Hoots, W.K.6
  • 103
    • 79951875993 scopus 로고    scopus 로고
    • Experience of four UK comprehensive care centres using FEIBA for surgeries in patients with inhibitors
    • Rangarajan, S., Yee, T.T. & Wilde, J. (2011) Experience of four UK comprehensive care centres using FEIBA for surgeries in patients with inhibitors. Haemophilia, 17, 28-34.
    • (2011) Haemophilia , vol.17 , pp. 28-34
    • Rangarajan, S.1    Yee, T.T.2    Wilde, J.3
  • 104
    • 79955139784 scopus 로고    scopus 로고
    • A retrospective study to describe the incidence of moderate to severe allergic reactions to factor IX in subjects with haemophilia B
    • Recht, M., Pollmann, H., Tagliaferri, A., Musso, R., Janco, R. & Neuman, W.R. (2011) A retrospective study to describe the incidence of moderate to severe allergic reactions to factor IX in subjects with haemophilia B. Haemophilia, 17, 494-499.
    • (2011) Haemophilia , vol.17 , pp. 494-499
    • Recht, M.1    Pollmann, H.2    Tagliaferri, A.3    Musso, R.4    Janco, R.5    Neuman, W.R.6
  • 105
    • 33646673204 scopus 로고    scopus 로고
    • Successful immune tolerance treatment with monoclonal or recombinant factor VIII concentrates in high responding inhibitor patients
    • Rocino, A. & de Biasi, R. (1999) Successful immune tolerance treatment with monoclonal or recombinant factor VIII concentrates in high responding inhibitor patients. Vox Sanguinis, 81, 35-38.
    • (1999) Vox Sanguinis , vol.81 , pp. 35-38
    • Rocino, A.1    de Biasi, R.2
  • 108
    • 34248512995 scopus 로고    scopus 로고
    • ELISA system for detection of immune responses to FVIII; a study of 246 samples and correlation with the Bethesda assay
    • Sahud, M.A., Pratt, K.P., Zhukov, O., Qu, K. & Thompson, A.R. (2007) ELISA system for detection of immune responses to FVIII; a study of 246 samples and correlation with the Bethesda assay. Haemophilia, 13, 317-322.
    • (2007) Haemophilia , vol.13 , pp. 317-322
    • Sahud, M.A.1    Pratt, K.P.2    Zhukov, O.3    Qu, K.4    Thompson, A.R.5
  • 109
    • 65449145067 scopus 로고    scopus 로고
    • Effect of rFVIIa dose and time to treatment on patients with haemophilia and inhibitors: analysis of HemoRec registry data from the Czech Republic
    • Salaj, P., Brabec, P., Penka, M., Pohlreichova, V., Smejka, P., Cetkovsky, P., Dusek, L. & Hedner, U. (2009) Effect of rFVIIa dose and time to treatment on patients with haemophilia and inhibitors: analysis of HemoRec registry data from the Czech Republic. Haemophilia, 15, 752-759.
    • (2009) Haemophilia , vol.15 , pp. 752-759
    • Salaj, P.1    Brabec, P.2    Penka, M.3    Pohlreichova, V.4    Smejka, P.5    Cetkovsky, P.6    Dusek, L.7    Hedner, U.8
  • 111
    • 33645573977 scopus 로고    scopus 로고
    • A prospective randomized trial of high and standard dosages of recombinant factor VIIa for treatment of hemarthroses in hemophiliacs with inhibitors
    • Santagostino, E., Mancuso, M.E., Rocino, A., Mancuso, G., Scaraggi, F. & Mannucci, P.M. (2006) A prospective randomized trial of high and standard dosages of recombinant factor VIIa for treatment of hemarthroses in hemophiliacs with inhibitors. Journal of Thrombosis and Haemostasis, 4, 367-371.
    • (2006) Journal of Thrombosis and Haemostasis , vol.4 , pp. 367-371
    • Santagostino, E.1    Mancuso, M.E.2    Rocino, A.3    Mancuso, G.4    Scaraggi, F.5    Mannucci, P.M.6
  • 112
    • 34248551364 scopus 로고    scopus 로고
    • Sequential therapy with activated prothrombin complex concentrate and recombinant factor VIIa in patients with severe haemophilia and inhibitors: update of our previous experience
    • Schneiderman, J., Rubin, E., Nugent, D.J. & Young, G. (2007) Sequential therapy with activated prothrombin complex concentrate and recombinant factor VIIa in patients with severe haemophilia and inhibitors: update of our previous experience. Haemophilia, 13, 244-248.
    • (2007) Haemophilia , vol.13 , pp. 244-248
    • Schneiderman, J.1    Rubin, E.2    Nugent, D.J.3    Young, G.4
  • 116
    • 0034762077 scopus 로고    scopus 로고
    • Elective surgery on factor VIII inhibitor patients using continuous infusion of recombinant activated factor VII: plasma factor VII activity of 10 IU/ml is associated with an increased incidence of bleeding
    • Smith, M.P., Ludlam, C.A., Collins, P.W., Hay, C.R., Wilde, J.T., Grigeri, A., Melsen, T. & Savidge, G.F. (2001) Elective surgery on factor VIII inhibitor patients using continuous infusion of recombinant activated factor VII: plasma factor VII activity of 10 IU/ml is associated with an increased incidence of bleeding. Thrombosis and Haemostasis, 86, 949-953.
    • (2001) Thrombosis and Haemostasis , vol.86 , pp. 949-953
    • Smith, M.P.1    Ludlam, C.A.2    Collins, P.W.3    Hay, C.R.4    Wilde, J.T.5    Grigeri, A.6    Melsen, T.7    Savidge, G.F.8
  • 117
    • 34548319248 scopus 로고    scopus 로고
    • Treatment of acquired haemophilia with recombinant activated FVII: a critical appraisal
    • Sumner, M.J., Geldziler, B.D., Pedersen, M. & Seremetis, S. (2007) Treatment of acquired haemophilia with recombinant activated FVII: a critical appraisal. Haemophilia, 13, 451-461.
    • (2007) Haemophilia , vol.13 , pp. 451-461
    • Sumner, M.J.1    Geldziler, B.D.2    Pedersen, M.3    Seremetis, S.4
  • 118
    • 77950207190 scopus 로고    scopus 로고
    • Major orthopaedic surgeries for haemophilia with inhibitors using rFVIIa
    • Takedani, H., Kawahara, H. & Kajiwara, M. (2010) Major orthopaedic surgeries for haemophilia with inhibitors using rFVIIa. Haemophilia, 16, 290-295.
    • (2010) Haemophilia , vol.16 , pp. 290-295
    • Takedani, H.1    Kawahara, H.2    Kajiwara, M.3
  • 121
    • 63049110965 scopus 로고    scopus 로고
    • Orthopaedic surgery in haemophilia patients with inhibitors: a practical guide to haemostatic, surgical and rehabilitative care
    • Teitel, J.M., Carcao, M., Lillicrap, D., Mulder, K., Rivard, G.E., St Louis, J., Smith, F., Walker, I. & Zourikian, N. (2009) Orthopaedic surgery in haemophilia patients with inhibitors: a practical guide to haemostatic, surgical and rehabilitative care. Haemophilia, 15, 227-239.
    • (2009) Haemophilia , vol.15 , pp. 227-239
    • Teitel, J.M.1    Carcao, M.2    Lillicrap, D.3    Mulder, K.4    Rivard, G.E.5    St Louis, J.6    Smith, F.7    Walker, I.8    Zourikian, N.9
  • 122
    • 77953213203 scopus 로고    scopus 로고
    • Successful low dose immune tolerance induction in severe haemophilia A with inhibitors below 40 Bethesda Units
    • Ter Avest, P.C., Fischer, K., Gouw, S.C., Van Dijk, K. & Mauser-Bunschoten, E.P. (2010) Successful low dose immune tolerance induction in severe haemophilia A with inhibitors below 40 Bethesda Units. Haemophilia, 16, 71-79.
    • (2010) Haemophilia , vol.16 , pp. 71-79
    • Ter Avest, P.C.1    Fischer, K.2    Gouw, S.C.3    Van Dijk, K.4    Mauser-Bunschoten, E.P.5
  • 124
    • 11044234837 scopus 로고    scopus 로고
    • Activated prothrombin complex concentrate (FEIBA) treatment during surgery in patients with inhibitors to FVIII/IX: the updated Norwegian experience
    • Tjønnfjord, G.E. (2004) Activated prothrombin complex concentrate (FEIBA) treatment during surgery in patients with inhibitors to FVIII/IX: the updated Norwegian experience. Haemophilia, 10(Suppl. 2), 41-45.
    • (2004) Haemophilia , vol.10 , Issue.SUPPL. 2 , pp. 41-45
    • Tjønnfjord, G.E.1
  • 125
    • 84872278570 scopus 로고    scopus 로고
    • FEIBA prophylaxis in hemophilia A patients with inhibitors results in 95% reduction in bleeding episodes. Abstract WFH Haemophilia.
    • Valentino, L. (2004) FEIBA prophylaxis in hemophilia A patients with inhibitors results in 95% reduction in bleeding episodes. Abstract WFH Haemophilia.
    • (2004)
    • Valentino, L.1
  • 126
    • 65449159707 scopus 로고    scopus 로고
    • The benefits of prophylactic treatment with APCC in patients with haemophilia and high-titre inhibitors: a retrospective case series
    • Valentino, L.A. (2009) The benefits of prophylactic treatment with APCC in patients with haemophilia and high-titre inhibitors: a retrospective case series. Haemophilia, 15, 733-742.
    • (2009) Haemophilia , vol.15 , pp. 733-742
    • Valentino, L.A.1
  • 127
    • 50049135947 scopus 로고    scopus 로고
    • Thrombin generation testing in routine clinical practice: are we there yet?
    • van Veen, J.J., Gatt, A. & Makris, M. (2008) Thrombin generation testing in routine clinical practice: are we there yet? British Journal of Haematology, 142, 889-903.
    • (2008) British Journal of Haematology , vol.142 , pp. 889-903
    • van Veen, J.J.1    Gatt, A.2    Makris, M.3
  • 130
    • 0031830491 scopus 로고    scopus 로고
    • Management of haemophilia B patients with inhibitors and anaphylaxis
    • Warrier, I. (1998) Management of haemophilia B patients with inhibitors and anaphylaxis. Haemophilia, 4, 574-576.
    • (1998) Haemophilia , vol.4 , pp. 574-576
    • Warrier, I.1
  • 131
    • 0031727621 scopus 로고    scopus 로고
    • Development of anaphylactic shock in haemophilia B patients with inhibitors
    • Warrier, I. & Lusher, J.M. (1998) Development of anaphylactic shock in haemophilia B patients with inhibitors. Blood Coagulation & Fibrinolysis, 9(Suppl. 1), S125-S128.
    • (1998) Blood Coagulation & Fibrinolysis , vol.9 , Issue.SUPPL. 1
    • Warrier, I.1    Lusher, J.M.2


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