Relationship between mean corpuscular volume and cognitive performance in older adults

Journal of the American Geriatrics Society

Volumn 61, Issue 1, 2013, Pages 84-89

  Gamaldo, Alyssa A ^a   Ferrucci, Luigi ^a   Rifkind, Joseph ^a   Longo, Dan L ^a   Zonderman, Alan B ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

cognition; mean corpuscular volume; older adults

Indexed keywords

ALBUMIN; CYANOCOBALAMIN; FERRITIN; FOLIC ACID; HEMOGLOBIN; IRON;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ANEMIA; ARTICLE; ATTENTION; BLOOD ANALYSIS; COGNITION; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROCYTE SEDIMENTATION RATE; EXECUTIVE FUNCTION; FEMALE; FERRITIN BLOOD LEVEL; FOLIC ACID BLOOD LEVEL; GERIATRIC ASSESSMENT; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; INFLAMMATION; IRON BLOOD LEVEL; LANGUAGE; LEUKOCYTE COUNT; LONGITUDINAL STUDY; MALE; MEAN CORPUSCULAR VOLUME; MENTAL HEALTH; NEUROPSYCHOLOGY; NORMAL HUMAN; VERBAL MEMORY; VISUAL MEMORY;

AGED; AGED, 80 AND OVER; AGING; COGNITION; COGNITION DISORDERS; ERYTHROCYTE INDICES; ERYTHROCYTES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MEMORY; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; RETROSPECTIVE STUDIES;

EID: 84872264671     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/jgs.12066     Document Type: Article

References (34)

1. Hershko C, Levy S, Matzner Y, et al. Prevalence and causes of anemia in elderly in Kiryat Shmnoa, Israel. Gerontology 1979; 25: 28-42.
2. Matzner Y, Levy S, Grossowicz N, et al. Prevalence and causes of anemia in elderly hospitalized patients. Gerontology 1979; 25: 113-119.
3. Lurie S, Gidron Y, Piper I, et al. Memory performance in late pregnancy and erythrocyte indices. J Soc Gynecol Investig 2005; 12: 293-296.
4. Shperling Tz, Danon D,. Age population distribution of erythrocytes in young and old healthy donors. Exp Gerontol 1990; 25: 413-422.
5. Baik HW, Russell RM,. Vitamin B12 deficiency in the elderly. Annu Rev Nutr 1999; 19: 357-377.
6. Kauwell GPA, Lippert BL, Wilsky CE, et al. Folate status of elderly women following moderate folate depletion responds only to a higher folate intake. J Nutr 2000; 130: 1584-1590.
7. Danon D, Bologna NB, Gavendo S,. Memory performance of young and old subjects related to their erythrocyte characteristics. Exp Geronotol 1992; 27: 275-285.
8. Polenakovic M, Sikole A,. Is erythropoietin a survival factor for red blood cells? J Am Soc Nephrol 1996; 7: 1178-1182.
9. Albert MS,. Age-related changes in cognitive function. In, Knoefel ML, Knoefel JE, eds. Clinical Neurology of Aging. New York: Oxford University Press, 1994, pp 314-328.
10. Baltes PB,. Theoretical propositions of life-span developmental psychology: On the dynamics of growth and decline. Develop Psychol 1987; 23: 611-626.
11. Park DC, Lautenschlager G, Heden T, et al. Models of visuospatial and verbal memory across the adult life span. Psychol Aging 2002; 17: 299-320.
12. Beghé C, Wilson A, Ershler WB,. Prevalence and outcomes of anemia in geriatrics: A systematic review of the literature. Am J Med 2004; 116: 3S-10S.
13. Dröge W, Schipper HM,. Oxidative stress and aberrant signaling in aging and cognitive decline. Aging Cell 2007; 6: 361-370.
14. Ferrucci L, Corsi A, Lauretani F, et al. The origins of age-related proinflammatory state. Blood 2005; 105: 2294-2299.
15. Sohal RS, Weindruch R,. Oxidative stress, caloric restriction, and aging. Science 1996; 273: 59-63.
16. Petersen RC,. Mild cognitive impairment as a diagnostic entity. J Intern Med 2004; 256: 183-194.
17. Kawas C, Gray S, Brookmeyer R, et al. Age-specific incidence rates of Alzheimer's disease: The Baltimore Longitudinal Study of Aging. Neurology 2000; 54: 072-077.
18. Lichtman MA, Kipps TJ, Kaushansky K, et al. Williams Hematology, 7th Ed. New York: McGraw-Hill, 2006.
19. Ajmani RS, Metter EJ, Jaykumar R, et al. Hemodynamic changes during aging associated with cerebral blood flow and impaired cognitive function. Neurobiol Aging 2000; 21: 257-269.
20. Sivan AB,. Benton Visual Retention Test, 5th Ed. San Antonio, TX: The Psychological Corporation, 1982.
21. Delis DC, Kramer JH, Kaplan E, et al. California Verbal Learning Test (CVLT). Adult Version, Research Ed. San Antonio, TX: The Psychological Corporation, 1987.
22. Benton AL, Hamsher KS,. Multilingual Aphasia Examination. Iowa City, IA: University of Iowa, 1976.
23. Goodglass H, Kaplan E,. Boston Diagnostic Aphasia Examination (BDAE). Philadelphia, PA: Lea and Febiger, 1983.
24. Ekstrom R, French J, Harman H,. Manual for Kit of Factor-Referenced Cognitive Tests. Princeton, NJ: Educational Testing Service, 1976.
25. Reitan R,. Validity of the trail making test as an indicator of organic brain disease. Percept Mot Skills 1958; 8: 271-276.
26. Blessed G, Tomlinson BE, Roth M,. The association between quantitative measures of dementia and of senile changes in the cerebral grey matter of elderly subjects. Br J Psychiatry 1968; 114: 797-811.
27. Folstein FW, Folstein SE, McHugh PR,. 'Mini-mental state': A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198.
28. Raudenbush SW, Bryk AS,. Hierarchical Linear Models: Applications and Data Analysis Methods, 2nd Ed. Thousand Oaks, CA: Sage, 2002.
29. Hox J,. Multilevel Analysis: Techniques and Applications. Mahwah, NJ: Erlbaum, 2002.
30. Preacher KJ, Curran PJ, Bauer DJ,. Computational tools for probing interactions in multiple linear regression, multilevel modeling, and latent curve analysis. J Educ Behav Statistics 2006; 31: 437-448.
31. Jucker M, Battig K, Meierruge W,. Effects of aging and vincamine derivatives on pericapillary microenvironment-stereological characterization of the cerebral capillary network. Neurobiol Aging 1990; 11: 39-46.
32. Beutler E, West C,. Hematologic differences between African-Americans and whites: The roles of iron deficiency and α-thalassemia on hemoglobin levels and mean corpuscular volume. Blood 2005; 15: 106-745.
33. Gamaldo AA, Ferrucci L, Rifkind JM, et al. Age-related changes in mean corpuscular volume in whites and African Americans. J Am Geriatr Soc 2011; 59: 1763-1764.
34. Patel KV, Harris TB, Faulhaber M, et al. Racial variation in the relationship of anemia with mortality and mobility disability among older adults. Blood 2007; 109: 4663-4670.