Mechanism of synergistic interactions and its influence on drug release from extended release matrices manufactured using binary mixtures of polyethylene oxide and sodium carboxymethylcellulose

Colloids and Surfaces B: Biointerfaces

Volumn 104, Issue , 2013, Pages 174-180

  Palmer, Dasha ^a   Levina, Marina ^a   Douroumis, Dionysios ^b   Maniruzzaman, Mohammed ^b   Morgan, David J ^c   Thomas P Farrell, ^a   Rajabi Siahboomi, Ali R ^a   Nokhodchi, Ali ^d,e  

^a Colorcon Limited ^*  (United States)

^b UNIVERSITY OF GREENWICH   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d MEDWAY SCHOOL OF PHARMACY   (United Kingdom)

^e TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Extended release tablets; Polyethylene oxide; Polymer combination; Synergistic effect

Indexed keywords

ACTIVE SUBSTANCE; ANIONIC POLYMERS; CATIONIC DRUGS; CHLORPHENIRAMINE MALEATE; DIFFUSION CONTROL; DRUG RELEASE; DRUG RELEASE MECHANISM; DRUG-POLYMER INTERACTION; EXTENDED RELEASE; H-BONDING; ISOTHERMAL TITRATION CALORIMETRY; MATRIX TABLET; NONIONIC POLYMERS; POLYMER-POLYMER INTERACTION; PROTONATED; RELEASE PROFILES; SINGLE POLYMERS; SODIUM CARBOXYMETHYLCELLULOSE; SYNERGISTIC EFFECT; SYNERGISTIC INTERACTION; VENLAFAXINE; VERAPAMIL HYDROCHLORIDE; X-RAY PHOTOELECTRONS;

AUTOMOBILE MANUFACTURE; BINARY MIXTURES; CALORIMETERS; DIFFERENTIAL SCANNING CALORIMETRY; DRUG INTERACTIONS; IONIC DRUGS; ISOTHERMS; PHOTOELECTRONS; POLYETHYLENE OXIDES; POLYETHYLENES; THERMOPLASTICS; TITRATION; X RAY PHOTOELECTRON SPECTROSCOPY;

POLYMERS;

CARBOXYLIC ACID; CARBOXYMETHYLCELLULOSE; CHLORPHENIRAMINE MALEATE; ESTER; MACROGOL; PROPRANOLOL; VENLAFAXINE; VERAPAMIL;

ARTICLE; CHEMICAL INTERACTION; COMPLEX FORMATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG INTERACTION; DRUG RELEASE; EXTENDED RELEASE TABLET; HYDROGEN BOND; ISOTHERMAL TITRATION CALORIMETRY; PRIORITY JOURNAL; TABLET FORMULATION; X RAY PHOTOELECTRON SPECTROSCOPY;

CALORIMETRY; CALORIMETRY, DIFFERENTIAL SCANNING; CARBOXYMETHYLCELLULOSE SODIUM; CHEMISTRY, PHARMACEUTICAL; CHLORPHENIRAMINE; CYCLOHEXANOLS; DRUG SYNERGISM; PHOTOELECTRON SPECTROSCOPY; POLYETHYLENE GLYCOLS; PROPRANOLOL; TABLETS; TIME FACTORS; VERAPAMIL;

APIS;

EID: 84872260198     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2012.11.025     Document Type: Article

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