Extended release of a large amount of highly water-soluble diltiazem hydrochloride by utilizing counter polymer in polyethylene oxides (PEO)/polyethylene glycol (PEG) matrix tablets

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 70, Issue 2, 2008, Pages 556-562

  Kojima, Hiroyuki ^a   Yoshihara, Keiichi ^a   Sawada, Toyohiro ^a   Kondo, Hiromu ^a   Sako, Kazuhiro ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Counter polymer; Diffusion; Drug release; Highly water soluble drug; Polymeric matrix tablet

Indexed keywords

CARBOMER; DILTIAZEM; MACROGOL; NICARDIPINE; NIFEDIPINE; PARACETAMOL;

ARTICLE; CONTROLLED DRUG RELEASE; CROSS LINKING; DRUG DIFFUSION; DRUG FORMULATION; DRUG SOLUBILITY; MATRIX TABLET;

DELAYED-ACTION PREPARATIONS; DILTIAZEM; POLYETHYLENE GLYCOLS; POLYMERS; SOLUBILITY; TABLETS;

EID: 52949090851     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.05.032     Document Type: Article

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